Morphological - lesional aspects of prosthetic mitral valve thrombosis

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The purpose of this paper is to present a case of prosthetic mitral valve thrombosis in a young patient with a history of acute articular rheumatism with bivalvular damage which required prosthetic mitral twin disc and tricuspid annuloplasty that, despite effective anticoagulation treatment, shows a high degree of mitral valve obstruction with severe hemodynamic disturbances that ultimately led to death.

The particularity of the case lies in the development of thrombosis in twin disc prosthesis type, complication that, in the literature, is cited as being more rarely met than the cases of single-disc prosthesis.

1. Vahanian, A., Lung, B., Pierard, L., Dion, R. & Pepper, L. (2009). Prosthetic valve surgery In Oxford University Press (Eds.), Camrn, A.J., Lucher, T., Serruys, P. The ESC textbook of cardiovascular medicine, second ed (pp. 806-817)

2. Jacob, R. & Troughton, R. (2009). Prosthetic heart valve. In Wolters Kluwer/Lippincott (Eds.), Griffin, B., Topol, E. Manual of cardiovascular medicine, third ed. (pp. 251-265)

3. Otto, C. & Bonow, R. (2008). Prosthetic cardiac valve. In Saunders Elsevier (Eds.), Libby, P., Bonow, R., Mann, D., Zipes, D. Braunwald's Heart Disease, eighth ed. (pp. 1682-1693)

4. Acar, C. & Theodore, P. (2010). Surgery for valvular heart disease. In Mosby-Elsevier (Eds.), Crawford, M., DiMarco, J., Paulus, W. Cardiology, third ed. (pp. 1345-1378)

5. Rahitmoola, S., Wu, Y.X., Grunkemeier, G. & Starr, A. (2008). Prosthetic heart valve: choice of valve and management of patient In Mc GrawHill Medical (Eds.), Fuster, V., O'Rourke, R., Walsh, R., PoolWilson, P. Hurst's The Heart, twelfth ed. (pp. 1783-1799)

6. Garcia, M. (2007). Prosthetic valve. In Lippincott Williams Wilkins (Eds.), Topol, E. Textbook of cardiovascular medicine, third ed. (pp. 389-401)

7. Vahanian, A., Baumgartner, H. & Bax, J. et al. (2001). Guidelines on the management of valvular heart disease. Eur Heart J., 28, 230-268

8. Bonow, R.O., Carabello, B.A. & ChateIjee, K. et al. (2006). ACC/AHA guidelines for the management of patients with valvular heart disease. J Am Coll Cardiol, 48(3), e1-148

9. Nishimura, R.A., Carabello, B.A. & Faxon, D.P. et al. (2008). ACC/AHA guidelines update on valvular heart disease. J Am Coll Cardiol, 52, 676-685

10. Zoghbi, W., Chambers, J. & Dumensnil, J. el al. (2009). Recommendations for evaluation of prosthetic valves with echocardiography and Doppler ultrasound. A report from ASE's guidelines and standards comrnitee and the task force on prosthetic valves. ASE, 22(9), 975-1014

11. Vongpatanasin, W., Hillis, D. & Lange, R. (1996). Prosthetic heart valves. N Eng J Med, 335(6), 407-416

12. Pibarot, P. & Dusmeshil, J.G. (2009). Prosthetic heart valves Selection of optimal prosthesis and long-term management. Circulation, 119, 1034-1048

13. Botzenhardt, F., Eichinger, W. & Bleiziffer, S. el al. (2005). Haemodynamic comparison of bioprostheses for complete supra annuIar position in patients with small aortic annulus. J Am Coll Cardiol, 45, 2054-2060

14. Webb, J. (2008). Percutaneous aortic valve replacement will become a common treatment for aortic valve disease. J Am Coll Cardiol, 1, 122-126

15. Vahanian, A. & Otto, C. (2010). Risk stratification of patients with aortic stenosis. Eur Heart J, DOI: 10.1093/Eurheart l/ehp 575

16. Scherptong, R., Vliegen, H. & Winter, M. el al. (2009). Tricuspid valve surgery in adults with a dysfunctional systemic right ventricle. Repair or replace? Circulation, 119, 1467-1472

17. Lurz, P., Coats, L. & Khambadkone, S. el al. (2008). Percutaneous pulmonary valve implantation. Impact of evolving technology and leaning curve on clinical outcome. Circulation, 117, 1964-1972

18. Montorsi, P., Cavoretto, D. & Alimento, M. et al. (2003). Prosthetic mitral valve thrombosis: can fluoroscopy predict the efficacy of thrombolytic treatment? CircuIation, 08 (suppl. II) II: 79-84

19. Pflederer, T. & Flachskampf, F. (2010). Echocardiographic follow-up after heart valve replacement. Heart, 96, 75-85

20. Schievano, S., Migliavacca, F. & Coats, L. el al. (2007). Percutaneous pulmonary valve implantation based on rapid prototypion on right ventricular outflow tract and pulmonary trunk from MR data. Radiology, 242(2), 490-497

21. Barbetseas, J., Nagueh, S. & Pitsavos, C. el al. (1998). Differentiating thrombus from pannus formation in obstructed mechanical prosthetic valves: an evaluation of c1inical, transthoracic and transesophageal echocardiographic parameters. J Am Coll Cardiol, 32, 1410-1417

22. David, T. (2005). Is prosthesis-patient mismatching a c1inically relevant entity? Circulation, 111, 3186-3187

23. Hoffinan, G., Lutter, G. & Cremer, L. (2008). Durability of bioprosthetic cardiac valves. Dtsch Artzeb, 106(8), 143-148

24. Colii, A., Verhoye, J.P. & Leguerrier, A. el al. (2007). Anticoagulation and antiplatelet therapy of bioprosthetic heart valve recipients: an unresolved issue. Eur J Cardio-thoracic Surgery, 31, 573-577

25. Elkayan, U. (2005). ValvuIar heart disease and pregnancy. J Am Coll Cardio1, 46, 403-410

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