Dietary Biotechnological Ajuga reptans Extract in Post Weaning Piglets: Effects on Growth Performance, Oxidative Status and Immune Parameters

Carlo Corino 1 , Michel Prost 2 , Grazia Pastorelli 3 , Sara Chiapparini 1  and Raffaella Rossi 1
  • 1 Department of Health, Animal Science and Food Safety, 20133, Milan, Italy
  • 2 Laboratoires SPIRAL, 21560, Dijon, France
  • 3 Department of Veterinary Medicine, 20133, Milan, Italy


The effect of dietary supplementation with a biotechnological extract of Ajuga reptans on growth performance, oxidative status and immune parameters was evaluated in post weaning piglets. At weaning, 120 piglets with an average live weight of 8.1±1.3 kg, were assigned to one of three experimental groups. The first group was fed a control diet (C). The second and third groups were fed the same diet supplemented with 5 mg (T1) and 10 mg (T2) of teupolioside/kg feed from a biotechnological plant extract. Growth performances were recorded and blood samples were collected at the beginning, at 14 days, and at the end of the trial (56 days). Serum biochemical parameters, oxidative status and immunoglobulin titres were determined. Average daily gain tended to be higher (P=0.057) and live weight was higher in piglets (P<0.05) fed with different amounts of plant extract (T1 and T2) than the controls. The production of reactive oxygen metabolites (ROMs) was higher (P<0.05) in the control group than in the groups receiving teupolioside (T1 and T2). Concentration of serum immunoglobulin of class G improved (P<0.001) in piglets fed the T1 and T2 diets than the controls. Overall, the results suggested that the biotechnological extract of Ajuga reptans containing teupolioside has an antioxidant and immunomodulant effect.

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