Migraine as the First Symptom for Setting a Clinical Diagnosis

The migraine is among the most frequent complains of the patients requesting a medical consultation. I am presenting hereby the case of a 34-year old patient, who complained of diffuse migraine followed several weeks later by vomiting and seizures. The brain computed tomography (CT) and magnetic resonance imaging (MRI) examinations indicate an intracranial spread located in the left (temporal) hemisphere, which had a mass effect on the ventricular system. When performing the extemporaneous examination, it was found an anaplastic oligodendroglioma. Subtotal resection under microscopic guidance was performed, as well as radiotherapy and chemotherapy after the surgery. When discharged from hospital, the patient was surgically cured and had an improved neurological state. The repeated checkups (clinical and paraclinical) indicated no signs of local relapse. Approximately 8 years after the first surgery, the patient returned for a check-up, in view of investigations and treatment, while complaining of migraine and a nervousness state that was bothering his family. The brain MRI indicated a large tumour relapse located in the left temporal-hippocampal region. The histopathology examination indicated that it was an anaplastic oligodendroglioma relapse. Surgery was performed and the tumour relapse located in the left temporal-hippocampal region was completely ablated. After the surgery, the patient was conscious and had no movement dysfunctions.