Sebaceous Carcinoma – Unexpected Tumor of the Nasal Ala Dorsum

At. Vlaykov 1 , At. Stefanov 1 , V. Velev 2 , M. Gulubova 2  and J. Ananiev 2
  • 1 Department of Otorhinolaryngology, Trakia University, Medical Faculty, Stara Zagora, Bulgaria
  • 2 Department of Clinical Pathology, Trakia University, Medical Faculty, Stara Zagora, Bulgaria

Abstract

Today, the extraocular variant of sebaceous carcinoma is still being poorly recognized. This type of carcinoma is rarely diagnosed correctly, which, together with its aggressive behavior, contributes to its poor prognosis. We present a case of an 84-year-old man with a history of left nasal ala tumor formation, diagnosed morphologically and immunohistochemically as sebaceous carcinoma.

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  • 1. Nelson BR, Hamlet KR, Gillard M et al. Sebaceous carcinoma. J Am Acad Dermatol. 1995;33:1-15.

  • 2. Bongu A, Lee ES, Peters SR, Chokshi RJ. Locally aggressive and multicentric recurrent extraocular sebaceous carcinoma: case report and literature review. Eplasty. 2013;21;13:e44.

  • 3. Cieza-Díaz DE, Cano-Martínez N, Barchino-Ortiz L, Longo-Imedio I. Extraocular sebaceous carcinoma: a report of 2 cases. Actas Dermosifiliogr. 2012;103(10):919-22.

  • 4. Shalin SC, Lyle S, Calonje E, Lazar AJ. Sebaceous neoplasia and the Muir-Torre syndrome: important connections with clinical implications. Histopathology. 2010;56(1):133-47.

  • 5. Rao NA, Hidayat AA, McLean IW, Zimmerman LE. Sebaceous carcinomas of the ocular adnexa: A clinicopathologic study of 104 cases, with five-year follow-up data. Hum Pathol. 1982;13(2):113-22.

  • 6. Dummer R, Pittelkow MR, Iwatsuki K et al. Skin Cancer – A World-Wide Perspective. Springer 2011. 153-154.

  • 7. Shields JA, Shields CL. Eyelid, Conjunctival and Orbital Tumours: atlas and textbook 2nd ed. Lippincott W&W 2008. 50-52.

  • 8. Cieza-Díaz DE, Cano-Martínez N, Barchino-Ortiz L, Longo-Imedio I. Extraocular sebaceous carcinoma: a report of 2 cases. Actas Dermosifiliogr. 2012;103(10):919-22.

  • 9. Nijhawan N, Ross MI, Diba R et al. Experience with sentinel lymph node biopsy for eyelid and conjunctival malignancies at a cancer center. Ophthal Plast Reconstr Surg 2004; 20: 291-295.

  • 10. Osada S, Ueno T, Inai S et al. Sebaceous carcinoma of the nose with a regional metastasis following false-negative sentinel lymph node biopsy. Acta Derm Venereol. 2011;91(3): 367-8.

  • 11. Alawi F, Siddiqui A. Sebaceous carcinoma of the oral mucosa: Case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005; 99: 79.

  • 12. Hornblass A, Lauer SA. Sebaceous carcinoma of the eyelids. Ophthalmology 2004; 111: 2149.

  • 13. Wick M, Swanson PE. Cutaneous adnexal tumors: a guide to pathologic diagnosis. Am Soc Clin Pathol. 1991;113:374-382.

  • 14. Phan K, Loya A. Mohs micrographic surgery versus wide local excision for sebaceous adenocarcinoma of the eyelid: Analysis of a national database. J Plast Reconstr Aesthet Surg. 2019 Mar 2. pii: S1748-6815(19)30074-9.

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