The minimum invasive dental concept is based on practical experience of more than 30 years negative trends from the use of resin materials in distal teeth and early metal-ceramic “aesthetic” crowns and bridges. The scientific dental research includes all aspects of the conservative dentistry treatment which are scientifically and clinically proved with most up to date methods and tests: anthropometric, epidemiological, biochemical, immunohistochemical, electron microscopy, polarized light microscopy, light induced fluorescence, microradiography, microbiology, genetic tests, etc. Experiments in vitro, animal tests, clinical research in the last 34 years are focused in the field of prevention of dental caries, treatment of precavitated precarious lesions with nanotechnologies, preparation of hard dental tissues with most conservative techniques, adhesive restoration methods with amalgam and resins, backup in endodontics in root canals preparation methods and in pins and posts fixations. The conclusions can be focused on basic principles and refocused in the 21st century like: Dental caries is not only predictable and controlled disease but is also a polyetiological disease on a community and population levels and uni- or bi-etiological on an individual level. The minimum invasive dental concept in cariology and endodontics leads to prevention of early extractions, early prosthetic medical procedures and to lifetime dental health. This plays a key role in prevention of metabolic disorders and gastrointestinal diseases.
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27. Boteva E. In vitro comparison of dentin bonding agent and cementum under composite material in cavities class I and II. Abstr. in English Annual Proceedings of IMAB, 8, 2002, 1, 64-67.
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29. Boteva Е, K. Peycheva. Detection of Dental Hypoplasia Ability of Fuorescence methods. Acta Medica Bulgarica, 40, 2013, 1, 61-64.
30. Boteva E, Karayasheva, M. Marinova Frequency of root caries in teeth with sound crowns. Car. Res. 47, 2013, 5, 439, Abstr. 62.
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33. Boteva E., K. Peycheva, D. Karayasheva. Frequency of iatrogenic changes caust from overhang restorations. Acta Medica Bulgarica, 42, 2015, 2, 30-35.
34. Boteva E. Minimum invasive dental concept in prevention and conservative treatment from research and science to practice. IJSR, 5, 2016, 11, 1325-1328.
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36. Karayasheva D., M. Marinova-Takorova, E. Boteva. A study on salivary clearance in dental caries prediction. Arch. of the Balkan Medical Union, vol.49, 2014, 3, 319-323.
37. Karayasheva D., M. Glushkova, T. Kadiyska, E. Boteva. Association study of the role of Glut 2 receptor in dental caries susceptibility, dietary habits and body mass index-BMI. International Journal of Science and Research, 5, 2016, 3, 83-86.
38. Karayasheva D., M. Glushkova, E. Boteva, V. Mitev, T. Kadiyska Association study for the role of Matrix metalloproteinases 2 and 3 gene polymorphisms in dental caries susceptibility. Arch Oral Biology, 68, 2016, 9-12.
39. Karayasheva D., M. Glushkova, T. Kadiyska, E. Boteva The role of matrix metalloproteinases (MMP2 and MMP3) gene polymorphisms in dental caries susceptibility. Caries Research 50, 2016, 27, Abstr. 59.
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42. Мarinova M., E. Boteva, K. Kalinov A study on the connection between root caries and periodontal disease. Comptes rendus, 69, 2016, 9, 1239-1244.
43. Peycheva K., E. Boteva. Methods for diagnosing dental fluorosis: Quantitative Laser fluorescence and Light-Indused fluorescence. Acta Medica Bulgarica, 40, 2013, 1, 53-60.
44. Peycheva K., E. Boteva. А Clinical study on dental fluorosis with Light Indused Fluorescence. IJSR, International Journal of Science and Research, 4, 3/2015, 1239-1241.
45. Peycheva K., E. Boteva. А comparison of different methods for fissure caries detection. Acta Medica Bulgarica, 43, 2016, 1, 30-38.
46. Peycheva K., D. Karayasheva, E. Boteva. Diagnostic abilities of light induced fluorescence LIF with SoproLife device. Caries Research 50, 2016, 61, Abstr. 137.
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