Polymorphisms in DNA repair genes: link with biomarkers of the CBMN cytome assay in hospital workers chronically exposed to low doses of ionising radiation / Polimorfizmi u genima za popravak DNA: poveznica s biomarkerima mikronukleus-testa u medicinskih radnika kronično izloženih niskim dozama ionizirajućeg zračenja

1. Berrington A, Darby SC, Weiss HA, Doll R. 100 years of observation on British radiologists: mortality from cancer and other causes 1897-1997. Br J Radiol 2001;74:507-19. doi: 10.1259/bjr.74.882.74050710.1259/bjr.74.882.74050711459730Search in Google Scholar

2. Wang JX, Zhang LA, Li BX, Zhao YC, Wang ZQ, Zhang JY, Aoyama T. Cancer incidence and risk estimation among medical X-ray workers in China. Health Phys 2002;82:455-66. PMID: 1190613410.1097/00004032-200204000-0000411906134Search in Google Scholar

3. Cardis E, Vrijheid M, Blettner M, Gilbert E, Hakama M, Hill C, Howe G, Kaldor D, Muirhead CR, Schubauer-Berigan M, Yoshimura T, Bermann F, Cowper G, Fix J, Hacker C, Heinmiller B, Marshall M, Thierry-Chef I, Utterback D, Ahn YO, Amoros E, Ashmore P, Auvinen A, Bae JM, Solano JB, Biau A, Combalot E, Deboodt P, Diez Sacristan A, Eklof M, Engels H, Engholm G, Gulis G, Habib R, Holan K, Hyvonen H, Kerekes A, Kurtinaitis J, Malker H, Martuzzi M, Mastauskas A, Monnet A, Moser M, Pearce MS, Richardson DB, Rodriguez-Artalejo F, Rogel A, Tardy H, Telle- Lamberton M, Turai I, Usel M, Veress K. Risk of cancer after low doses of ionising radiation: retrospective cohort study in 15 countries. Br Med J 2005;331:77-80. doi: 10.1136/ bmj.38499.599861.E010.1136/bmj.38499.599861.E055861215987704Search in Google Scholar

4. Metz-Flamant C, Samson E, Caër-Lorho S, Acker A, Laurier D. Leukemia risk associated with chronic external exposure to ionizing radiation in a French cohort of nuclear workers. Radiat Res 2012;178:489-98. doi: 10.1667/RR2822.110.1667/RR2822.123050984Search in Google Scholar

5. Kopjar N, Kašuba V, Milić M, Rozgaj R, Želježić D, Gajski G, Mladinić M, Garaj-Vrhovac V. Normalne i granične vrijednosti mikronukleus-testa na limfocitima periferne krvi u ispitanika opće populacije Republike Hrvatske [Normal and cut-off values of the cytokinesis-block micronucleus assay on peripheral blood lymphocytes in the Croatian general population, in Croatian]. Arh Hig Rada Toksikol 2010:61:219-34. doi: 10.2478/10004-1254-61-2010-202710.2478/10004-1254-61-2010-202720587397Search in Google Scholar

6. Fenech M. Cytokinesis-block micronucleus cytome assay. Nat Protoc 2007;2:1084-104. doi: 10.1038/nprot.2007.7710.1038/nprot.2007.7717546000Search in Google Scholar

7. Hu JJ, Smith TR, Miller MS, Mohrenweiser HW, Golden A, Case LD. Amino acid substitution variants of APE1 and XRCC1 genes associated with ionizing radiation sensitivity. Carcinogenesis 2001;22:917-22. doi: 10.1093/ carcin/22.6.91710.1093/carcin/22.6.91711375899Search in Google Scholar

8. Aka P, Mateuca R, Buchet JP, Thierens H, Kirsch-Volders M. Are genetic polymorphisms in OGG1, XRCC1 and XRCC3 genes predictive for the DNA strand break repair phenotype and genotoxicity in workers exposed to low dose ionising radiations? Mutat Res 2004;556:169-81. PMID: 1549164510.1016/j.mrfmmm.2004.08.00215491645Search in Google Scholar

9. Angelini S, Kumar R, Carbone F, Maffei F, Cantelli-Forti G, Violante FS, Lodi V, Curti S, Hemminki K, Hrelia P. Micronuclei in humans induced by exposure to low level of ionizing radiation: influence of polymorphims in DNA repair genes. Mutat Res 2005;570:105-17. PMID: 1568040810.1016/j.mrfmmm.2004.10.00715680408Search in Google Scholar

10. Andreassi MG, Foffa I, Manfredi S, Botto N, Cioppa A, Picano E. Genetic polymorphisms in XRCC1, OGG1, APE1 and XRCC3 DNA repair genes, ionizing radiation exposure and chromosomal DNA damage in interventional cardiologists. Mutat Res 2009;666:57-63. doi: 10.1016/j. mrfmmm.2009.04.003Search in Google Scholar

11. Kapka L, Baumgartner A, Siwińska E, Knudsen LE, Anderson D, Mielzyńska D Environmental lead exposure increases micronuclei in children. Mutagenesis 2007;22:201-7. doi: 10.1093/mutage/gem00410.1093/mutage/gem00417311805Search in Google Scholar

12. Fenech M, Chang WP, Kirsch-Volders M, Holland N, Bonassi S, Zeiger E. HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures. Mutat Res 2003;534:65-75. PMID: 1250475510.1016/S1383-5718(02)00249-8Search in Google Scholar

13. Eastmond DA, Tucker JD. Kinetochore localization in micronucleated cytokinesis-blocked Chinese hamster ovary cells: a new and rapid assay for identifying aneuploidyinducing agents. Mutat Res 1989;224:517-25. PMID: 268559210.1016/0165-1218(89)90079-7Search in Google Scholar

14. Hu JJ, Mohrenweiser HW, Bell DA, Leadon SA, Miller MS. Symposium overview: genetic polymorphisms in DNA repair and cancer risk. Toxicol Appl Pharmacol 2002;185:64-73. PMID: 1246073810.1006/taap.2002.9518Search in Google Scholar

15. Godderis L, Aka P, Mateuca R, Kirsch-Volders M, Lison D, Veulemans H. Dose dependent influence of genetic polymorphisms on DNA damage induced by styrene oxide, ethylene oxide and gamma-radiation. Toxicology 2006;219:220-9. doi: 10.1016/j.tox.2005.11.02110.1016/j.tox.2005.11.021Search in Google Scholar

16. Stata Corporation. Stata Statistical software, release 11. College Station, TX: stata Corporation; 2011.Search in Google Scholar

17. Vral A, Fenech M, Thierens H. The micronucleus assay as a biological dosimeter of in vivo ionizing radiation exposure. Mutagenesis 2011;26:11-7. doi: 10.1093/mutage/geq07810.1093/mutage/geq078Search in Google Scholar

18. Fučić A, Markučič D, Mijić A, Jazbec AM. Estimation of genome damage after exposure to ionizing radiation and ultrasound used in industry. Environ Mol Mutagen 2000;36:47-51. PMID: 1091835910.1002/1098-2280(2000)36:1<47::AID-EM7>3.0.CO;2-ASearch in Google Scholar

19. Cardoso RS, Takahashi-Hyodo S, Peitl P Jr, Ghilardi-Neto T, Sakamoto-Hojo ET. Evaluation of chromosomal aberrations, micronuclei, and sister chromatid exchanges in hospital workers chronically exposed to ionizing radiation. Teratog Carcinog Mutagen 2001;21:431-9. PMID: 1174625610.1002/tcm.1030Search in Google Scholar

20. Maffei F, Angelini S, Cantelli-Forti G, Lodi V, Violante FS, Mattioli S, Hrelia P. Micronuclei frequency in hospital workers occupationally exposed to low levels of ionizing radiation: influence of smoking status and other factors. Mutagenesis 2002;17:405-9. doi: 10.1093/mutage/17.5.40510.1093/mutage/17.5.405Search in Google Scholar

21. Hadjidekova VB, Bulanova M, Bonassi S, Neri M. Micronucleus frequency is increased in peripheral blood lymphocytes of nuclear power plant workers. Radiat Res 2003;160:684-90. PMID: 1464079510.1667/RR3074Search in Google Scholar

22. Zakeri F, Hirobe T. A cytogenetic approach to the effects of low levels of ionizing radiations on occupationally exposed individuals. Eur J Radiol 2010;73:191-5. doi: 10.1016/j. ejrad.2008.10.015Search in Google Scholar

23. Sakly A, Gaspar JF, Kerkeni E, Silva S, Teixeira JP, Chaari N, Cheikh HB. Genotoxic damage in hospital workers exposed to ionizing radiation and metabolic gene polymorphisms. J Toxicol Environ Health A 2012;75:934-46. doi: 10.1080/15287394.2012.69071010.1080/15287394.2012.690710Search in Google Scholar

24. Maluf SW, Passos DF, Bacelar A, Speit G, Erdtmann B. Assessment of DNA damage in lymphocytes of workers exposed to X-radiation using the micronucleus test and the comet assay. Environ Mol Mutagen 2001;38:311-5. doi: 10.1002/em.1002910.1002/em.10029Search in Google Scholar

25. Thierens H, Vral A, Barbé M, Meijlaers M, Baeyens A. Chromosomal radiosensitivity study of temporary nuclear workers and the support of the adaptive response induced by occupational exposure. Int J Rad Biol 2002;78:1117-26. doi: 10.1080/095530002100003471010.1080/0955300021000034710Search in Google Scholar

26. Sari-Minodier I, Orsiere T, Auquier P, Martin F, Botta A. Cytogenetic monitoring by use of the micronucleus assay among hospital workers exposed to low doses of ionising radiation. Mutat Res 2007;629:111-21. PMID: 1742872310.1016/j.mrgentox.2007.01.009Search in Google Scholar

27. Dutra A, Pak E, Wincovitch S, John K, Poirier MC, Olivero OA. Nuclear bud formation: a novel manifestation of Zidovudine genotoxicity. Cytogen Genome Res 2010;128:105-10. doi: 10.1159/00029879410.1159/000298794Search in Google Scholar

28. Bonassi S, Fenech M, Lando C, Lin YP, Ceppi M, Chang WP, Holland N, Kirsch-Volders M, Zeiger E, Ban S, Barale R, Bigatti MP, Bolognesi C, Jia C, Di Giorgio M, Ferguson LR, Fucic A, Lima OG, Hrelia P, Krishnaja AP, Lee TK, Migliore L, Mikhalevich L, Mirkova E, Mosesso P, Müller WU, Odagiri Y, Scarffi MR, Szabova E, Vorobtsova I, Vral A, Zijno A. HUman MicroNucleus project: international database comparison for results with the cytokinesis-block micronucleus assay in human lymphocytes: I effects of laboratory protocol, scoring criteria, and host factors on the frequency of micronuclei. Environ Mol Mutagen 2001;37:31-45. PMID: 1117024010.1002/1098-2280(2001)37:1<31::AID-EM1004>3.0.CO;2-PSearch in Google Scholar

29. Donmez-Altuntas H, Bitgen N. Evaluation of the genotoxicity and cytotoxicity in the general population in Turkey by use of the cytokinesis-block micronucleus cytome assay. Mutat Res 2012;748:1-7. doi: 10.1016/j.mrgentox.2012.05.01310.1016/j.mrgentox.2012.05.013Search in Google Scholar

30. Dias FL, Antunes LM, Rezende PA, Carvalho FE, Silva CM, Matheus JM, Oliveira JV Jr, Lopes GP, Pereira GA, Balarin MA. Cytogenetic analysis in lymphocytes from workers occupationally exposed to low levels of ionizing radiation. Environ Toxicol Pharmacol 2007;23:228-33. doi: 10.1016/j. etap.2006.10.003Search in Google Scholar

31. Eken A, Aydin A, Erdem O, Akay C, Sanal HT, Soykut B, Sayal A, Somuncu I. Cytogenetic analysis of peripheral blood lymphocytes of hospital staff occupationally exposed to low doses of ionizing radiation. Toxicol Ind Health 2010;26:273-80. doi: 10.1177/074823371036569310.1177/0748233710365693Search in Google Scholar

32. Bonassi S, Neri M, Lando C, Ceppi M, Lin Y, Chang WP, Holland N, Kirsch-Volders M, Zeiger E, Fenech M; The HUMN collaborative group. Effect of smoking habits on the frequency of micronuclei in human lymphocytes: results from the Human MicroNucleus project. Mutat Res 2003;543:155-66. PMID: 1264418510.1016/S1383-5742(03)00013-9Search in Google Scholar

33. Damiola F, Byrnes G, Moissonnier M, Pertesi M, Deltour I, Fillon A, Le Calvez-Kelm F, Tenet V, McKay-Chopin S, McKay JD, Malakhova I, Masyakin V, Cardis E, Lesueur F, Kesminiene A. Contribution of ATM and FOXE1 (TTF2) to risk of papillary thyroid carcinoma in Belarusian children exposed to radiation. Int J Cancer 2014;134:1659-68. doi: 10.1002/ijc.2848310.1002/ijc.28483Search in Google Scholar

34. Salnikova L, Chumachenko A, Belopolskaya O, Rubanovich A. Correlations between DNA polymorphism and frequencies of gamma-radiation induced and spontaneous cytogenetic damage. Health Phys 2012;103:37-41. doi: 10.1097/HP.0b013e3182231a9d10.1097/HP.0b013e3182231a9dSearch in Google Scholar

35. Cho YH, Kim YJ, An YS, Woo HD, Choi SY, Kang CM, Chung HW. Micronucleus-centromere assay and DNA repair gene polymorphisms in lymphocytes of industrial radiographers. Mutat Res 2009;680:17-24. doi: 10.1016/j. mrgentox.2009.08.007Search in Google Scholar

36. Rzeszowska-Wolny J, Polanska J, Pietrowska M, Palyvoda O, Jaworska J, Butkiewicz D, Hancock R. Influence of polymorphisms in DNa repair genes XPD, XRCC1 and MGMT on DNA damage induced by gamma radiation and its repair in lymphocytes in vitro. Radiat Res 2005;164:132-40. PMID: 1603858410.1667/RR3400Search in Google Scholar

37. Mohrenweiser HW, Wilson DM, Jones IM. Challenges and complexities in estimating both the functional impact and the disease risk associated with the extensive genetic variation in human DNA repair genes. Mutat Res 2003;526:93-125. PMID: 1271418710.1016/S0027-5107(03)00049-6Search in Google Scholar

38. Roos WP, Binder A, Böhm L. Determination of the initial DNA damage and residual DNA damage remaining after 12 hours of repair in eleven cell lines at low doses of irradiation. Int J Radiat Biol 2000;76:1493-500. PMID: 1109885210.1080/0955300005017625211098852Search in Google Scholar

39. Touil N, Aka PV, Buchet JP, Thierens H, Kirsch-Volders M. Assessment of genotoxic effects related to chronic low level exposure to ionizing radiation using biomarkers for DNA damage and repair. Mutagenesis 2002;17:223-32. PMID: 11971994 10.1093/mutage/17.3.22311971994Search in Google Scholar