In vivo toxicity of a new antifungal agent 2,4-dithiophenoxy-1-iodo-4-bromo benzene: a follow up on our in vitro study / In vivo toksičnost novoga antimikotika 2,4-ditiofenoksi-1-jodo-4-bromobenzena: proširenje in vitro istraživanja

1. Infectious Diseases Society of America. Statement of the IDSA concerning Bioshield II: Responding to an everchanging threat’. Alexandria, VA: IDSA; 2004.Search in Google Scholar

2. Sun QY, Zhang WN, Xu JM, Cao YB, Wu QY, Zhang DZ, Liu CM, Yu SC, Jiang YY. Synthesis and evaluation of novel 1-(1H-1,2,4-triazol-1-yl)-2-(2,4-difluorophenyl)-3-[(4- substitutedphenyl)-piperazin-1-yl]-propan-2-ols as antifungal agents. Eur J Med Chem 2007;42:1151-7. doi: 10.1016/j.ejmech.2006.11.00310.1016/j.ejmech.2006.11.003Search in Google Scholar

3. Hilley Vensel TD. Fluconazole: a valuable fungistatic. Primary Car Update for OB/GYNS 2002;9:181-3. doi: 10.1016/S1068-607X(02)00115-410.1016/S1068-607X(02)00115-4Search in Google Scholar

4. Loğoğlu E, Arslan S, Öktemer A. In vitro biological activity studies of thioethoxy- and thiophyenoxyhalobenzene derivatives. Heterocycl Comm 2006;12:219-24. doi: 10.1515/HC.2006.12.3-4.21910.1515/HC.2006.12.3-4.219Search in Google Scholar

5. Süloğlu AK, Karacaoğlu E, Koçkaya EA, Selmanoğlu G, Loğoğlu E. Cytotoxic effects of a novel thialo benzene derivative 2,4-dithiophenoxy-1-Iodo-4-bromo benzene (C18H12S2IB) in L929 cells. Int J Toxicol 2014;33:319-24. doi: 10.1177/109158181453043710.1177/1091581814530437Search in Google Scholar

6. Food and Drug Administration (FDA). DIFLUCAN® (Fluconazole Tablets) (Fluconazole for Oral Suspension) [displayed 2 March 2015]. Available at http://www.accessdata.fda.gov/drugsatfda_docs/label/2014/019949s060,020090s044lbl.pdfSearch in Google Scholar

7. Park K, Williams DP, Naisbitt DJ, Kitteringham NR, Pirmohamed M. Investigation of toxic metabolites during drug development. Toxicol Appl Pharmacol 2005;207(Suppl 2):425-34. PMID: 1599669910.1016/j.taap.2005.02.029Search in Google Scholar

8. Joly V, Bolard J, Yeni P. In vitro models for studying toxicity of antifungal agents. Antimicrob Agents Chemother 1992;36:1799-804. PMC 19218910.1128/AAC.36.9.1799Search in Google Scholar

9. National Research Council. Guide for the Care and Use of Laboratory Animals. Eighth edition, 2011 [displayed 13 February 2015]. Available at http://grants.nih.gov/grants/olaw/Guide-for-the-care-and-use-of-laboratory-animals.pdfSearch in Google Scholar

10. Pappas PG, Rex JH, Sobel JD, Filler SG, Dismukes WE, Walsh TJ, Edwards JE. Guidelines for treatment of Candidiasis. Clin Infect Dis 2004;38:161-89. doi: 10.1086/38079610.1086/380796Search in Google Scholar

11. Kılıç A, Akay MT. A three generation study with genetically modified Bt corn in rats: Biochemical and histopathological investigation. Food Chem Toxicol 2008;46:1164-70. doi: 10.1016/j.fct.2007.11.01610.1016/j.fct.2007.11.016Search in Google Scholar

12. Babu PP, Yoshida Y, Su M, Segura M, Kawamura S, Yasui N. Immunohistochemical expression of Bcl-2, Bax and cytochrome c following focal cerebral ischemia and effect of hypothermia in rat. Neurosci Lett 2000;291:196-200. PMID: 1098464010.1016/S0304-3940(00)01404-XSearch in Google Scholar

13. Koçkaya EA, Kılıç Süloğlu A, Karacaoğlu E, Selmanoğlu G. Vinclozolin Exposure throughout pregnancy and its developmental toxicity. Toxicol Res 2014;3:375-83. doi: 10.1039/C4TX00037D10.1039/C4TX00037DSearch in Google Scholar

14. Waxman DJ, Holloway MG. Sex differences in the expression of hepatic drug metabolizing enzymes. Mol Pharmacol 2009;76:215-28. doi: 10.1124/mol.109.05670510.1124/mol.109.056705271311819483103Search in Google Scholar

15. Sellers RS, Morton D, Michael B, Roome N, Johnson J.K, Yano BL, Perry R, Schafer K. Society of Toxicologic Pathology Position Paper: Organ weight recomendations for toxicology studies. Toxicol Pathol 2007;35:751-5. PMID: 1784935810.1080/0192623070159530017849358Search in Google Scholar

16. Fortoul TI, Piñón-Zarate G, Diaz-Bech ME, González- Villalva A, Mussali-Galante P, Rodriguez-Lara V, Colin- Barenque L, Martinez-Pedraza M, Montaño LF. Spleen and bone marrow megakaryocytes as targets as targets for inhaled vanadium. Histol Histopathol 2008;23:1321-6. PMID: 18785114Search in Google Scholar

17. Benko I, Hernadi F, Megyeri A, Kiss A, Somogyi G, Tegyey Z, Kraicsovits F, Kovács P. Comparison of the toxicity of fluconazole and other azole antifungal drugs to murine and human granulocyte-macrophage progenitor cells in vitro. J Antimicrob Chemother 1999;43:675-81. doi: 10.1093/ jac/43.5.67510.1093/jac/43.5.67510382889Search in Google Scholar

18. Feng L, Xia Y, Yoshimura T, Wilson CB. Modulation of neutrophil influx in glomerulonephritis in the rat with antimacrophage inflammatory protein-2 (MIP-2) antibody. J Clin Invest 1995;95:1009-17. doi: 10.1172/JCI11774510.1172/JCI1177454414347883948Search in Google Scholar

19. González-Flecha B, Cutrin JC, Boveris A. Time course and mechanism of oxidative stress and tissue damage in rat liver subjected to in vivo ischemia-reperfusion. Clin Invest 1993;91:456-64. doi: 10.1172/JCI11622310.1172/JCI1162232879558432855Search in Google Scholar

20. Miller TJ, Knapton A, Adeyemo O, Noory L, Weaver J, Hanig JP. Cytochrome c: a non-invasive biomarker of druginduced liver injury. J Appl Toxicol 2008;28:815-28. doi: 10.1002/jat.134710.1002/jat.134718418843Search in Google Scholar