Coexistence of pancreatic adenocarcinoma and a pseudocyst in cat

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Abstract

Exocrine pancreatic tumors in cats and dogs are very uncommon, with exocrine pancreatic adenocarcinoma described as a particularly rare, malignant tumor in a small animals. It is usually derived from pancreatic ducts, as well as glandular tissue. Very often the disease has a subclinical course and is diagnosed only during post – mortem examination. Adenocarcinoma metastasize to both the surrounding and distant organs. The etiology of the cancer progress in the pancreas remains unknown.

Pancreatic pseudocyst (pseudocystis pancreatis) is a very rare disease in domestic animals. Only a few cases of pancreatic pseudocyst in dogs and cats are described in the available literature. On the other hand, in humans it is a common complication of pancreatitis. The pancreatic pseudocyst can be a result of pancreatitis, as well as be a secondary condition to acute pancreatitis, trauma or chronic inflammation. It is a capsule made of fibrous or granulation tissue, containing sterile pancreatic juice. The pathogenesis of pancreatic pseudocyst is still unknown. Clinical signs are not specific and may resemble symptoms of pancreatitis. The ultrasound examination shows a cyst in the pancreas.

This paper describes the case of pancreatic adenocarcinoma in a cat that occurred simultaneously with the pancreatic pseudocyst. Currently, literature indicates the necessity to differentiate the above cancer from cystic lesion. Due to the simultaneous occurrence of both pathologies, extremely rare diagnosis and spectacular picture of changes, it was decided to present this case.

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  • 1. Rosatelli P Menicagli F Citro G Baldi a. Spugnini EP. Long-Term Survival in a Cat with Pancreatic Carcinoma and Splenic Involvement after Surgical Excision. Case Reports Vet Med. 2011;2011:1–3; DOI: 10.1155/2011/653859.

  • 2. Sapierzyński R. Nowotwory układu pokarmowego u psów i kotów. Częśc III. Nowotwory ślinianek wątroby i części zewnątrzwydzielniczej trzustki. Życie Weter. 2006;81(6):388–95.

  • 3. Linderman MJ Brodsky EM de Lorimier L-P Clifford CA Post GS. Feline exocrine pancreatic carcinoma: a retrospective study of 34 cases. Vet Comp Oncol. 2013;11(3):208–18; DOI: 10.1111/j.1476-5829.2012.00320.x.

  • 4. Sapierzyński R. Onkologia praktyczna psów i kotów. Wrocław: Elsevier Urban & Partner. 2010.

  • 5. Steiner JM. Choroby przewodu pokarmowego psów i kotów. Galaktyka. 2009:283–304.

  • 6. Andrews LK. Tumors of the exocrine pancreas. In: Diseases of the cat. Saunders. 1987:505–7.

  • 7. Seaman RL. Exocrine Pancreatic Neoplasia in the Cat: A Case Series. J Am Anim Hosp Assoc. 2004;40(3):238–45; DOI: 10.5326/0400238.

  • 8. Haines VL Brown PR Hruban RH Huso DL. Adenocarcinoma of the Hepatopancreatic Ampulla in a Domestic Cat. Vet Pathol. 1996;33(4):439–41; DOI: 10.1177/030098589603300413.

  • 9. Brown PJ Mason K V. Merrett DJ Mirchandani S Miller RI. Multifocal necrotising steatites associated with pancreatic carcinoma in three dogs. J Small Anim Pract. 1994;35(3):129–32; DOI: 10.1111/j.1748-5827.1994.tb03913.x.

  • 10. Brooks DG Campbell KL Dennis JS Dunstan RW. Pancreatic paraneoplastic alopecia in three cats. J Am Anim Hosp Assoc. 1994;30:557–63.

  • 11. Godfrey DR. A case of feline paraneoplastic alopecia with secondary Malassezia-associated dermatitis. J Small Anim Pract. 1998;39(8):394–6.

  • 12. Coleman MG Robson MC Harvey C. Pancreatic cyst in a cat. N Z Vet J. 2005;53(2):157–9; DOI: 10.1080/00480169.2005.36495.

  • 13. VanEnkevort BA O’Brien RT Young KM. Pancreatic pseudocysts in 4 dogs and 2 cats: ultrasonographic and clinicopathologic findings. J Vet Intern Med. 1999;13(4):309–13; DOI: 10.1111/j.1939-1676.1999.tb02186.x.

  • 14. Hines BL Salisbury SK Jakovljevic S DeNicola DB. Pancreatic pseudocyst associated with chronic-active necrotizing pancreatitis in a cat. J Am Anim Hosp Assoc. 1996;32(2):147–52; DOI: 10.5326/15473317-32-2-147.

  • 15. Fojut-Pałka B. Torbiele trzustki u psów i kotów. Mag Weter. 2013; 22(196):844–7.

  • 16. Coleman M Robson M. Pancreatic Masses Following Pancreatitis: Pancreatic Pseudocysts Necrosis and Abscesses. Compend Contin Educt Pr Vet. 2005;27(2):147–54.

  • 17. Marchevsky AM Yovich JC Wyatt KM. Pancreatic pseudocyst causing extrahepatic biliary obstruction in a dog. Aust Vet J. 2000;78(2):99–101; DOI: 10.1111/j.1751-0813.2000.tb10534.x.

  • 18. Panagiotis M. Ultrasonography of the Gastrointestinal Tract and Pancreas of the Dog and Cat. Iran J Vet Surg. 2008;Supplement:57–62.

  • 19. Bellenger CR Ilkiw JE Malik R. Cystogastrostomy in the treatment of pancreatic pseudocyst/abscess in two dogs. Vet Rec. 1989;125(8):181–4.

  • 20. Smith S Biller D. Resolution of a pancreatic pseudocyst in a dog following percutaneous ultrasonographic-guided drainage. J Am Anim Hosp Assoc. 1998;34(6):515–22; DOI: 10.5326/15473317-34-6-515.

  • 21. Branter EM Viviano KR. Multiple recurrent pancreatic cysts with associated pancreatic inflammation and atrophy in a cat. J Feline Med Surg. 2010;12(10):822–7; DOI: 10.1016/j.jfms.2010.06.005.

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