Leiomyoma is a benign tumour, originating from smooth muscles cells. This tumor commonly involves the uterus, vagina, stomach, intestine, urinary bladder and other organs. Only a few cases of splenic leiomyoma in dogs have been reported in the available literature. Much more frequently malignant leiomyosarcoma was found. The aim of this study was to compile rare clinical case of splenic leiomyoma in dog, which developed with no clinical signs and no abnormalities in blood findings. A 14-year-old, spayed bitch was examined with ultrasonography, where lesions on the spleen were identified. Based on the clinical findings (blood test in norm, no metastases in X-ray examination) surgical removal of spleen was recommended. Two fragments of tumors were prepare for histopathological examination. The lesion was described as smooth muscle benign tumor, therefore a diagnosis of leiomyoma was made. About a year after splenectomy no signs of metastases were present in a ultrasound and X-ray examinations. This report indicates the necessity of taking the occurrence of benign lesions in the spleen into account. Splenectomy based on the presence of tumor lesion should be associated with histopathological examination to identify the nature of change. This clinical case, despite a marked morphological lesion shown during intraoperative examination, was benign with successful prognosis.
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1. Dąbrowski R. Szachowicz A. Brodzki P. and Śmiech A. “Leiomyoma u suki – opis przypadku” Weter. w Prakt. vol. 8 pp. 56-58 2011.
2. Madej J. A. and Rotkiewicz T. Patologia ogólna zwierząt. Olsztyn: Wydawnictwo Uniwersytetu Warmińsko – Mazurskiego w Olsztynie 2006.
3. Sapierzyński R. Onkologia praktyczna psów i kotów. Wrocław: Elsevier Urban & Partner 2010.
4. Madej J. A. Rotkiewicz T. and Nozdryn-Płotnicki Z. Patologia szczegółowa zwierząt. Olsztyn: Wydawnictwo Uniwersytetu Warmińsko – Mazurskiego w Olsztynie 2007.
5. Laluha P. Grest P. Eichenberger S. Reusch C. E. and Gerber B. “Leiomyom einer Niere beim Hund – eine seltene Diagnose” Schweiz Arch Tierheilkd vol. 148 no. 6 pp. 303-307 2006.
6. Mathes R. L. Noble S. J. and Ellis A. E. “Leiomyoma of the third eyelid in a dog” Vet. Ophthalmol. vol. 19 no. 4 pp. 347-354 2016.
7. Gallay J. Bélanger M. C. Hélie P. Côté E. Johnson T. O. and Peters M. E. “Cardiac leiomyoma associated with advanced atrioventricular block in a young dog” J. Vet. Cardiol. vol. 13 no. 1 pp. 71-77 2011.
8. Sarais V. et al. “Human Chorionic Gonadotrophin as a Possible Mediator of Leiomyoma Growth during Pregnancy: Molecular Mechanisms” Int. J. Mol. Sci. vol. 18 no. 9 2017.
9. Holdsworth-Carson S. J. Zaitseva M. Vollenhoven B. J. and Rogers P. A. W. “Clonality of smooth muscle and fibroblast cell populations isolated from human fibroid and myometrial tissues” Mol. Hum. Reprod. vol. 20 no. 3 pp. 250-259 2014.
10. Cohen M. Post G. S. and Wright J. C. “Gastrointestinal leiomyosarcoma in 14 dogs.” J. Vet. Intern. Med. vol. 17 no. JANUARY 2003 pp. 107-110 2003.
11. Spangler W. L. Culbertson M. R. and Kass P. H. “Primary mesenchymal (nonangiomatous /nonlymphomatous) neoplasms occurring in the canine spleen: anatomic classification immunohistochemistry and mitotic activity correlated with patient survival.” Vet. Pathol. vol. 31 no. 1994 pp. 37-47 1994.
12. Irausquin R. A. et al. “Comparative evaluation of the liver in dogs with a splenic mass by using ultrasonography and contrast-enhanced computed tomography.” Can. Vet. J. vol. 49 no. 1 pp. 46-52 2008.
13. Eberle N. Babo V. Von Nolte I. Baumgärtner W. and Betz D. “Splenic masses in dogs” Tpk.Schattauer.De vol. 40 no. 10 pp. 250-260 2012.
14. Glińska-Suchocka K. Jankowski M. Borusewicz P. Spużak J. and Kubiak K. “Choroby śledziony – cz. II. Niesymetryczne powiększenie narządu.” Weter. w Prakt. vol. 11 pp. 41-45 2014.