Identification of the Herbal Drug Prunellae spica based on Macroscopic and Microscopic Characteristics

Abstract

Prunella vulgaris L. belongs to the genus Prunella, Lamiaceae family, Nepetoideae subfamily. In Romania, the genus Prunella includes Prunella vulgaris L., Prunella grandiflora (L.) Jacq and Prunella laciniata L.. Amongst these, Prunella vulgaris is of particular importance, having numerous pharmacological actions. The purpose of this study is to analyze macroscopically and microscopically the main characters by which Prunellae spica can be identified and distinguished from other fruit-spikes from species of the Lamiaceae family.

If the inline PDF is not rendering correctly, you can download the PDF file here.

  • 1. Dınç M, Dogu S (2012) Anatomical and micromorphological studies on Teucrium sect. Isotriodon (Lamiaceae) in Turkey with a taxonomic note. Biologia 67(4):663-672. https://doi.org/10.2478/s11756-012-0049-2.

  • 2. Dinç M, Pinar NM, Dogu S, Yildiriml S (2009) Micromorphological studies of Lallemantia L. (Lamiaceae) species growing in Turkey, Acta Biol Crac Ser Bot 51(1):45-54.

  • 3. Duke J (2001) Prunella vulgaris, Handbook of Edible Weeds. CRC; pp 158

  • 4. Feng ML, Jia LL, Wu YP (2000) Effect of the Alcoholic Extraction of Spica Prunellae on Experimental Diabetic Nephropathy. J Shaanxi Coll Tradit Chin Med 1:7-9.

  • 5. Gu X, Li Y, Mu J, Zhang (2013) Chemical Constituents of Prunella vulgaris, J Environ Sci (China) 25; S1:S161-163. https://doi.org/10.1016/S1001-0742(14)60648-3

  • 6. Gu XJ, Li YB, Li P, Qian SH, Zhang JF (2007) Triterpenoid Saponins from the Spikes of Prunella vulgaris. Helvet Chim Acta 90: 72-78. https://doi.org/10.1002/hlca.200790023

  • 7. Hodișan I, Pop I (1976) Botanică sistematică, Editura Didactică și Pedagogică București, pp. 400.

  • 8. Hon-Yeung C, Qing-Feng Z (2008) Enhanced analysis of triterpenes, flavonoids and phenolic compounds in Prunella Vulgaris L. by capillary zone electrophoresis with the addition of running buffer modifiers. J Chromatogr A 1213(2): 231-238. doi: 10.1016/j.chroma.2008.10.033

  • 9. Huynh HT, Teel RW (1999) Selective Induction of Apoptosis in Human Mammary Cancer Cells (MCF-7) by Pycnogenol. Anticancer Res, 1999; 20: 2417-2420.

  • 10. Hwang YJ, Lee EJ, Kim HR, Hwang KA (2013) In vitro antioxidant and anticancer effects of solvent fractions from Prunella vulgaris var. lilacina. BMC Complement Altern Med 13:310. doi: 10.1186/1472-6882-13-310

  • 11. Khare CP (2007) Indian Medicinal Plants: An Illustrated Dictionary. Springer; 103.

  • 12. Kozlowska M, Laudy AE, Przbyl J, Ziarno M, Majewska E (2015) Chemical composition and antibacterial activity of some medicinal plants from Lamiaceae family. Acta Pol Pharm 72(4):757-767.

  • 13. Mohsen SM, Ammar AS (2009) Total phenolic contents and antioxidant activity of corn tassel extracts. Food Chem 112(3):595–598. doi:10.1016/j.foodchem.2008.06.014

  • 14. Moon HK, Hong SP, Smets E, Huysmans S (2009) Micromorphology and Character Evolution of Nutlets in Tribe Mentheae (Nepetoideae, Lamiaceae). Systematic Botany 34(4):760–776. https://doi.org/10.1600/036364409790139592

  • 15. Psotova J, Kolar M, Sousek J, Švagera Z, Vičar J, Ulrichová J (2003) Biological Activities of Prunella vulgaris Extract. Phytother Res 17:1082-1087. doi:0.1002/ptr.1324

  • 16. Raafat K, Wurglics M, Schubert-Zsilavecz M (2016) Prunella vulgaris L. active components and their hypoglycemic and antinociceptive effects in alloxan-induced diabetic mice. Biomed Pharmacoter 84:1008-1018. doi: 10.1016/j.biopha.2016.09.095

  • 17. Sârbu I, Ștefan N, Oprea A (2013) Plante Vasculare din România - Determinator ilustrat de teren, Editura Victor B Victor, București 18-22: 650.

  • 18. Tamaș M (1999) Botanică farmaceutică vol III, Ed. Medicală, Cluj; pp. 215.

  • 19. Trochon V, Blot E, Cymbalista F, Engelmann C, Tang RP, Thomaïdis A, Vasse M, Soria J, Lu H, Soria C (2000) Apigenin Inhibits Endothelial-Cell Proliferation in G2/M Phase Whereas It Stimulates Smooth-Muscle Cells by Inhibiting P21 and P27 Expression, Intern J Cancer 85: 691-696.

  • 20. Wang SJ, Wang XH, Dai YY, Ma MH, Rahman K, Nian H, Zhang H (2019) Prunella vulgaris: A Comprehensive Review of Chemical Constituents, Pharmacological Effects and Clinical Applications. Curr Pharm Des 25(3):356-369. https://doi.org/10.2174/1381612825666190313121608

  • 21. *** Europea Pharmacopeiaea, 8th edition, 2011, pp. 1219-1220.

OPEN ACCESS

Journal + Issues

Search