<abstract xmlns="http://www.w3.org/1999/xhtml"><italic>Artemisia annua</italic> is an important medical plant that produces artemisinin used for its antimalarial, antibacterial and antifungal effects in modern medicine. The high demand and low artemisinin content in plants (0.01-2 %) has led to studies about alternative methods to increase yield. Biofertilizers (beneficial microbes and/or biological products that colonize roots, improve plant nutrition and growth) have been reported affecting secondary metabolism and the production of active ingredients of herbs. The purpose of this paper is to draw attention to the current status of the research on mutualistic and endophytic microorganism of <italic>A. annua</italic> that have the potential to increase the quality and quantity of the crude drugs, derived from the herb. Scientific papers in this field focus on the effects on inoculation with different microorganisms (arbuscular micorrhizal fungi, endophytic bacteria and fungi) and the isolation of endophytes from <italic>A. annua</italic>. Bioinoculants can affect biomass, artemisinin and essential oil concentration, disease resistance, nutrient status, phosphatase activity, foliar glandular trichome density, leaf chlorophyll content, guaiacol peroxidase enzyme concentration, stomatal conductance and transpiration rate, and plant growth parameters (total weight, leaf yield, height, seed yield). The endophytes isolated from the plant are potential artemisinin content and plant stress resistance enhancers.</abstract>

Mutualistic and Endophytic Microorganisms of <italic>Artemisia Annua</italic>: Description, Role and Use

<abstract xmlns="http://www.w3.org/1999/xhtml">The village of Ulieş belongs to Râciu Commune. It is located in the south-eastern part of the Transylvanian Plain (N46°41’30” E24°23’56”) in a hilly region crossed by wide valleys. It is situated at 24 km distance from Tîrgu Mureș, in the contact area of Mădăraş Hills and Comlod Hills, on the middle stream of the Comlod River (or Lechința) and its tributaries. The paper aims were the study of the flora from the surroundings of Ulieş Village, the investigation of possible medicinal use of the encountered plants species, and the preservation of plant diversity from the area. Fieldworks were conducted in 2014-2017. A total of 415 vascular plant taxa belonging to 76 families were identified. From these, 185 species are medicinal plants with certain content of active principles. Plants containing tannins (13.51%) were in higher percentage followed by those with essential oils (12.97%), saponins (10.81%), alkaloids (8.10%), flavonoids (7.56%), coumarins (7.02%), mucilages (5.94%), iridoids (5.40%), phenolic glycosides (3.78%), anthraquinone derivatives and cardiotonic glycosides (3.24), organic acids, vitamins and provitamins (3.78%), bitter principles (2.70), bitter-aromatic principles (2.16%), etc.</abstract>

Department of Fundamental Pharmaceutical Sciences, Discipline of Pharmaceutical Botany

University of Medicine, Pharmacy, Sciences and Technology of Tîrgu Mureș

The Medicinal Importance of Wild Plants from the Surroundings of Ulieş Village, Mureş County

<abstract xmlns="http://www.w3.org/1999/xhtml">The herbarium of Gyula Erazmus Nyárády has been assessed to contain around 90.000 sheets. During the past thirty years, the legacy of the famed botanist still found in public institutions and private collection across Romania and Hungary has been studied and processed by Kálmán Váczy, Sándor Bartha and especially Katalin Bartók. However, nothing is known about the sheets that had ended up outside Hungary or Romania. This study proposes to fill this gap to some extent: firstly, it draws attention to sheets from Nyárády’s herbarium found in the inventory of the world’s biggest botanical gardens, museums and universities of natural science; secondly, it goes into details about the circumstances of collecting the prepared taxa, and the conclusions that can be drawn from this; it presents the reasons why some sheets got abroad; and it adds more data to reconstruct Nyárády’s social network. It also indicates that the heritage, now known to consist of around 90.000 sheets, can be completed with the sheets found abroad.</abstract>

The Herbarium Files of Gyula Erazmus Nyárády which Got Abroad

<abstract xmlns="http://www.w3.org/1999/xhtml">The aim of this study is to evaluate the possibility of using hemp shives as natural amendments in a phytoremediation sequence. Thus, plant growth tests were conducted for rapeseed (<italic>Brassica napus</italic>) and flax (<italic>Linum usitatissimum</italic>) in vegetation pots with sandy soil. These were seeded in a cadmium artificial contaminated environment with or without hemp shives. The efficiency of hemp shives as natural amendments was evaluated after 40 days of initiating experimental model, by evaluation of plant growth and development of plants through biometric and gravimetric measurements. Also, the concentration of assimilatory pigments was determined. In order to establish bioaccumulation capacity, degree of recovery and translocation factor, it was determined the concentration of cadmium metal ions absorbed in various parts of rapeseed and flax plants. It has been found that the development of the root system is more pronounced in the presence of hemp shives both in contamination with cadmium ions and in the absence. By determining cadmium concentrations accumulate in various parts of the plant have been shown that supplementing growth media with hemp shives, improves the bioaccumulation process of cadmium ions. According to the results, the hemp shives can be used as amendments in phytoremediation process, enhancing bioaccumulation process.</abstract>

University of Medicine, Pharmacy, Sciences and Technology of Tîrgu Mureş

Faculty of Chemical Engineering and Environmental Protection

Gheorghe Asachi Technical University of Iași

Hemp Shives as Natural Amendments in Crops of Rapeseed (<italic>Brassica napus</italic>) and Flax (<italic>Linum usitatissimum</italic>)

<abstract xmlns="http://www.w3.org/1999/xhtml">The review summarizes the main roles of ferulic acid (4-hydroxy-3-methoxy-cinnamic acid), a phenolic compound widespread in the vegetable world, being present in cereals (rice, wheat, oats), coffee, tomatoes, nuts or corn, but also in a range of plants used in Traditional Chinese Medicine. It plays a vital role in ensuring cell wall rigidity and also in the formation of other important organic compounds for plants. Ferulic acid has a wide variety of biological activities such as: antioxidant, anti-inflammatory, antimicrobial, antiallergic, anticancer, antithrombotic, antiviral activities, vasodilator, hepatoprotective and metal chelation actions, enzymatic activity modulation, and wound healing activity. The most important action is the antioxidant one, being studies that demonstrate that ferulic acid acts synergistically with other antioxidants. Also, the antioxidant effect of ferulic acid is enhanced by skin exposure to ultraviolet light, making it a good ingredient for sunscreen cosmetics. It is one of the most powerful natural antioxidant that has the potential to neutralize free radicals, to slow down the aging process of the skin, to accelerate skin regeneration, to heal the skin wounds and also to preserve the health and beauty of the skin.</abstract>

“Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Pharmacy

“Dunărea de Jos” University Galaţi, Faculty of Medicine and Pharmacy

Ferulic Acid – A Versatile Molecule

<abstract xmlns="http://www.w3.org/1999/xhtml">Isoflavonoids are phytoestrogenic compounds found mainly in plants from the Fabaceae family and also in soy-based foods. Isoflavonoids exhibit (anti)estrogenic effects, acting on estrogen receptors due to the structural similarities with estrogenic hormones (17β-estradiol). The aim of our minireview is to highlight the pharmacokinetic and pharmacodynamic properties of isoflavonoids, in order to sustain the beneficial effects in different pathologies (osteoporosis associated with menopause, breast cancer, prostate cancer, protective cognitive functions) but, at the same time, to aware about the possible adverse effects on long-term administration.</abstract>

Department of Fundamental Pharmaceutical Sciences, Discipline of Biochemistry and Environmental Chemistry

Department of Fundamental Pharmaceutical Sciences, Discipline of Analytical Chemistry and Drug Analysis

Isoflavonoids − Dual Action on Estrogen Receptors

AHEAD OF PRINT

Volume 6 (2023): Issue 2 (December 2023)

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Volume 1 (2018): Issue 1 (June 2018)

Acta Biologica Marisiensis

 Acta Biologica Marisiensis (ABM) is an official Journal of the University of Medicine, Pharmacy, Science and Technology “George Emil Palade” of Târgu Mureș, Romania, and is published twice a year. The peer-reviewed journal is dedicated to the life sciences and publishes articles in the following fields: biochemistry, botany, cell biology and molecular biology, biotechnology, ecology, genetics, microbiology, pharmacognosy, phytochemistry.  Both original research papers and reviews are welcomed. The journal addresses the entire academic community of specialists and researchers activate in different fields of life sciences and pharmacy, and its goal is to provide them the latest research developments in their field of activity.  Acta Biologica Marisiensis is the official publication of the University of Medicine, Pharmacy, Science and Technology “George Emil Palade” of Târgu Mureș, being published by University Press. The journal is published in every year since 1964 under the name Note Botanice. Since 2018 it is published with a new name, Acta Biologica Marisiensis, included as a new series in Acta Marisiensis.  The journal publishes high-quality articles on various subjects dedicated to the life sciences in the following fields: biochemistry, botany, cell biology and molecular biology, biotechnology, ecology, genetics, microbiology, pharmacognosy, phytochemistry.   Why subscribe and read   It is an international peer-reviewed, open access journal published two times per year, only in English language.  The Journal is designed to facilitate the exchange of ideas between researchers from different countries all around the world.  The Journal has high standards for its contents. It has good publishing quality in electronic and printed form.   Why submit   the Journal is always freely available online  fast, fair and constructive peer review procedure  no payment for article processing or publishing fee is required from authors  free publication of color figures, graphs and tables in published articles  immediate publication of articles  worldwide dissemination and unrestricted access to all published articles  high quality publishing, available in both forms, electronic and printed  promotion of each article in numerous abstracting databases   Archiving  Sciendo archives the contents of this journal in Portico - digital long-term preservation service of scholarly books, journals and collections.  Plagiarism Policy  The editorial board is participating in a growing community of Similarity Check System's users in order to ensure that the content published is original and trustworthy. Similarity Check is a medium that allows for comprehensive manuscripts screening, aimed to eliminate plagiarism and provide a high standard and quality peer-review process. 

Acta Biologica Marisiensis

Volume 1 (2018): Issue 2 (December 2018)

Mutualistic and Endophytic Microorganisms of Artemisia Annua: Description, Role and Use

The Medicinal Importance of Wild Plants from the Surroundings of Ulieş Village, Mureş County

The Herbarium Files of Gyula Erazmus Nyárády which Got Abroad

Hemp Shives as Natural Amendments in Crops of Rapeseed (Brassica napus) and Flax (Linum usitatissimum)

Ferulic Acid – A Versatile Molecule

Isoflavonoids − Dual Action on Estrogen Receptors

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