Children with intermittent or constant abdominal pain are common and can pose significant concerns to their parents and guardians [1]. In most cases, children with abdominal pain require only a good history, physical examination and some simple laboratory tests to rule out specific causes. If detailed history, physical examinations and simple laboratory tests fail to suggest any specific causes, the abdominal pain is not serious and the children will get better without treatment [1]. However, a significant proportion of children have chronic abdominal pain that lasts a long time or happens over and over again without any clues from history, physical examinations, and common tests [1]. Constant search for alarm findings will be needed in these children.
Some alarm findings warrant further investigations [2, 3, 4, 5], such as involuntary weight loss, persistent abdominal pain and vomiting, gastrointestinal bleeding, chronic diarrhea, unexplained fever, urinary abnormalities, family history of peptic ulcer disease, oral aphthous ulcers, and localized abdominal pain. Alarm findings suggestive of
When a suspicion for
The sensitivity of biopsy urease testing is high [6]. This diagnostic technique is less expensive than histology in confirming the presence of
However, the consensus group of the European Society for Paediatric Gastroenterology Hepatology and Nutrition/North American Society for Pediatric Gastroenterology recommended that invasive diagnostic testing for
As recommended by the European and North American consensus group, to reach the aim of a 90% eradication rate with initial therapy, antibiotics should be tailored according to susceptibility testing. This would require the result of bacterial culture and sensitivity test to tailor antibiotic regimens accordingly [9].
Therefore, endoscopic investigation of chronic abdominal pain in children may be appropriate given the presence of alarm findings. However, whether we need to wait for the result of bacterial culture and susceptibility testing is not completely answered. The risk and benefit of waiting for the result of bacterial culture and sensitivity test warrant further investigations to optimize cure rate and prevent unwarranted inappropriate use of antibiotics.
Since most chronic pain in children is functional in nature, the first goal of treatment is to help the child return to normal activities such as schooling and playing with other children. It may take time to find the causes of the pain and its treatment. Therefore, health providers and family members must help the child cope with pain via building good relationship between providers, parents and the children. This will render providers to manage the pain either functional or organic by offering sympathy, support and reassurance and avoid reinforcing the pain by giving it undue attention.