Prevalence of vitamin D deficiency in Thai patients receiving various modalities of renal replacement therapy
Article Category: Original article
Published Online: Mar 31, 2017
Page range: s39 - s48
DOI: https://doi.org/10.5372/1905-7415.1000.520
Keywords
© 2016 Piyawan Kittiskulnam, Paweena Susantitaphong, Natavudh Townamchai, Pisut Katavatin, Khajohn Tiranathanagul, Talerngsak Kanjanabuch, Yingyos Avihingsanon, Kearkiat Praditpornsilpa, Somchai Eiam-Ong
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Background
Vitamin D status of Thai patients receiving renal replacement therapy (RRT) is incompletely known.
Objectives
To determine the prevalence of vitamin D deficiency or insufficiency in adult Thai patients receiving various RRT modalities, and factors associated with low vitamin D levels.
Methods
In this retrospective, observational, single-center, cross-sectional study, we evaluated dialysis-related laboratory test variables from 111 patients receiving RRT. Serum 25-hydroxyvitaminD concentration [25(OH)D] < 15 ng/mL was defined as deficiency, and 15–30 ng/mL as insufficiency.
Results
Low vitamin D levels were identified in 100% patients receiving peritoneal dialysis (PD; 81% deficient, 19% insufficient), 94% patients receiving online-hemodiafiltration (OL-HDF; 50% deficient, 44% insufficient), and 100% patients with kidney transplants (KT; 55% deficient, 45% insufficient). PD patients showed significantly lower serum [25(OH)D] than OL-HDF or KT patients (10.5 ± 5.9 vs 17.7 ± 8.5 vs 15.4 ± 6.1 ng/mL respectively,
Conclusions
Nearly 100% patients receiving RRT had vitamin D deficiency or insufficiency, and RRT modalities might be related.