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Identification of coronaviral antibodies and coronavirus - specific antibody complexes in ascites fluid of cats diagnosticated with feline infectious peritonitis

.H.L., Carstens, E.B., Estes, M.K., Lemon, S.M., Maniloff, J., Mayo, M.A., McGeoch, D.J., Pringle, C.R., Wickner, R.B. (Eds) - Virus Taxonomy , Classification and Nomenclature of Viruses, Academic 339 Press, New York, pp. 835-849. Erles K., C. Toomey, H. Brooks, J. Brownlie, 2003 - Detection of a group 2 coronavirus in 345 dogs with canine infectious respiratory disease. Virology 310, 216-223. Gorbalenya A. E., L. Enjuanes, J. Ziebuhr, E.J. Snijder, 2006 - Nidovirales: evolving the 354 largest RNA virus genome. Virus Res., 117, 17

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Coronaviruses in avian species – review with focus on epidemiology and diagnosis in wild birds

enable them to switch to new hosts ( 49 ). These newly created viruses can acquire zoonotic potential, as witnessed by the severe acute respiratory syndrome (SARS), the epidemic from Southern China in 2003 caused by SARS-CoVs. This disease, termed “atypical pneumonia”, was diagnosed in humans in 29 countries and had a nearly 10% mortality rate. In 2012, there emerged a subsequent disease caused by a novel coronavirus, the so-called Middle East respiratory syndrome (MERS) with even higher mortality rates. Both SARS- and MERS-CoVs crossed the species barrier from bats to

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Etiological and Pathomorphological Investigations in Calves with Coronaviral Pneumoenteritis

REFERENCES 1. Alenius, S., Niskanen, R., Junti, N., Larsso, B. (1991). Bovine coronavirus as the causative agent of winter dysentery: serological evidence. Acta Vet Scand. 32, 163-170. PMid:1666489 2. Yang, D., Leibowitz, L. (2015). The structure and functions of coronavirus genomic 3′ and 5′ ends. Virus Res. 206, 120-133. PMid:25736566 PMCid:PMC4476908 3. Hansa, A., Rai, R., Dhama, K., Wani, M. (2012). ELISA screening of faecal samples for bovine coronavirus and virus detection by RT-PCR in

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The 2019 Novel Coronavirus: A Crown Jewel of Pandemics?

Starting from the December 2019 identification of the 2019 novel coronavirus (2019-nCoV), an overwhelming sense of panic has enveloped public discourse. This is likely to be amplified by WHO recently declaring the novel coronavirus outbreak a public health emergency of international concern. It is the third significant occurrence of a zoonotic coronavirus crossing the species barrier to infect humans, and it likely will not be the last. Hope is not lost; and a measured approach, one that is cognizant of the seriousness of this public health crisis without

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The Middle East Respiratory Syndrome Coronavirus (Mers-CoV) – What is the Risk? A Review of Recent Studies

.A., Abedi G.R., Al Nsour M., Iblan I., Jarour N., Farag N.H., Haddadin A., Al-Sanouri T., Tamin A., Harcourt J.L., Kuhar D.T., Swerdlow D.L., Erdman D.D., Pallansc h M.A., Haynes L.M., Gerber S.I., Jordan MERS-Co V Investigation Team. (2014). Hospitalassociated outbreak of Middle East respiratory syndrome coronavirus:aserologic, epidemiologic, and clinical description. Clin. Infect. Dis., 59: 1225-1233. Al-Tawfiq J.A., Memish Z.A. (2014). Middle East respiratory syndrome coronavirus: epidemiology and disease control measures. Infect. Drug. Resist., 7: 281

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Design, synthesis and molecular docking of novel triazole derivatives as potential CoV helicase inhibitors

REFERENCES 1. R. L. Graham, E. F. Donaldson and R. S. Baric, A decade after SARS: strategies for controlling emerging coronaviruses, Nat. Rev. Microbiol . 11 (2013) 836–848; 2. V. S. Raj, H. Mou, S. L. Smits, D. H. Dekkers, M. A. Müller, R. Dijkman, D. Muth, J. A. Demmers, A. Zaki, R. A. Fouchier, V. Thiel, C. Drosten, P. J. Rottier, A. D. Osterhaus, B. J. Bosch and B. L. Haagmans, Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC, Nature 495 (2013) 251–254; https

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ABC of viral infections in hematology: focus on herpesviruses

) caused by Orthomyxoviruses (e.g., influenza A/B), Paramyxoviruses (e.g., human parainfluenza virus PIV-1, -2, -3, and -4; respiratory syncytial virus RSV-A and -B), Picornaviruses (e.g., human rhinovirus), coronaviruses (e.g., human coronavirus), Pneumoviridiae (e.g., human metapneumovirus), and potentially other viruses. Diagnostics of viral infections in hematological patients Laboratory test for viral infections with focus on latent and chronic infections should be performed in many hematological conditions, especially at diagnosis of the disease, and before

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Analyzing the MERS disease control strategy through an optimal control problem

References Abboubakar, M., Kamgang, J. and Tieudjo, D. (2015). Backward bifurcation and control in transmission dynamics of arboviral diseases, Mathematical Biosciences 278(1): 100-129. Al-Tawfiq, J., Smallwood, C., Arbuthnott, K., Malik, M.S., Barbeschi, M. and Memish, Z. (2012). Emerging respiratory and novel coronavirus 2012 infections and mass gatherings, East Mediterr Health Journal 19(1): 48-54. Aldila, D., Nuraini, N. and Soewono, E. (2014). Optimal control problem of preventing of swine flu disease

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Researches on vicinal immune responses in canine leptospirosis


Leptospirosis is a zoonosis of constant importance as causative microbial agent, maintained by subclinical infections in wild and domestic animals. Currently, for active immunization in dogs is used an inactivated vaccine, produced by specialized companies in different countries. The vast majority are polyvalent vaccines, which include the two leptospire serovars (Leptospira canicola and Leptospira icterohaemorhagiae) and viral antigens for prevention of infectious hepatitis Rubarht, Carré's disease, coronavirus and parainfluence. Specific immunity induced by this inactivated vaccine, is active, individual, installs in 10 to 21 days after administration, lasting a variable time (4-6 months) and never causes a 100% protection. This paper aims to investigate how this immune response in carnivores and its protection.

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The Influence of Probiotic Lactobacilli and Flaxseed on the Health of Weaned Piglets and Metabolism of Polyunsaturated Fatty Acids (PUFAs)


This study investigated for 14 days post-weaning, the influence of dietary supplementation of synbiotics in the form of probiotic cheeses containing cultures of L. plantarum and L. fermentum and crushed flaxseed (source of ω-3 polyunsaturated fatty acids — PUFAs and fibre) on 36 commercial piglets originating from an infected herd (Coronavirus and E. coli) during the critical period of weaning. We focused on the health and metabolism of PUFAs in this critical period of a piglet’s life. The dietary supplementation positively affected: the overall health state of weaners, reduced diarrhoea by 29 % by 14 days post-weaning and significantly increased the counts of lactic acid bacteria, bifidobacteria and the production of volatile fatty acids. The PUFA concentrations in the m. biceps femoris of the piglets were analysed by gas chromatography. High levels of ω-3 alpha-linolenic acid (ALA) in flaxseed increased significantly the level of ALA, eicosapentaenic acid (EPA) and docosahexaenic acid (DHA) in the pig muscles on days 7 and 14 post-weaning. The levels of ω-6 linolenic acid (LA) were less affected by the diet, but were increased on day 14 post-weaning, while the conversion products of LA, and arachidonic acid (AA), were decreased on days 7 and 14. The increased level of dietary ALA favoured the activity of Δ-6-desaturase for the conversion of ALA to EPA and DHA, at the expense of AA synthesis from LA. The ability of synbiotics to incorporate high levels of DHA in the pig muscles appear prospective for improving the nutritional properties of pork and reducing the occurrence of civilization diseases in consumers of this product of animal origin.

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