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Mario Ciliberto, Fabio Maggi, Giorgio Treglia, Federico Padovano, Lucio Calandriello, Alessandro Giordano and Lorenzo Bonomo

for the staging and follow-up of patients with metastasis. Eur J Radiol 2009; 70: 393-400. 5. Lambregts DM, Maas M, Cappendijk VC, Prompers LM, Mottaghy FM, Beets GL, et al. Whole-body diffusion-weighted magnetic resonance imaging: Current evidence in oncology and potential role in colorectal cancer staging. Eur J Cancer 2011; 47: 2107-16. 6. Thomson V, Pialat JB, Gay F, Coulon A, Voloch A, Granier A, et al. Wholebody MRI for metastases screening: a preliminary study using 3D VIBE sequences with automatic subtraction between

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David Laszlo Tarnoki, Adam Domonkos Tarnoki, Antje Richter, Kinga Karlinger, Viktor Berczi and Dirk Pickuth

References 1. Ladd SC, Ladd ME. Perspectives for preventive screening with total body MRI. Eur Radiol 2007; 17: 2889-97. 2. Fenchel M, Requardt M, Tomaschko K, Kramer U, Stauder NI, Naegele T, et al. Whole-body MR angiography using a novel 32-receiving-channel magnetic resonance (MR) system with surface coil technology: first clinical experience. J Magn Reson Imaging 2005; 21: 596-603. 3. Sans S, Kesteloot H, Kromhout D. The burden of cardiovascular diseases mortality in Europe. Task Force of the European

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Salih Gültekin, Alper Dilli, Ata Arıkök, Hasan Bostancı and Ahmet Hasdemir

, Daly PL, Shakir KM. Littoral cell angioma presenting as metastatic thyroid carcinoma to the spleen. Thyroid 2005; 15 : 170-5. Siegelman ES, Outwater EK. Tissue characterization in the female pelvis by means of MR imaging. Radiology 1999; 212 : 5-18. Siegel MJ. Magnetic resonance imaging of the adolescent female pelvis. Magn Reson Imaging Clin N Am 2002; 10 : 303-24. Podobnik J, Kocijančič I, Kovac V, Sersa I. 3T MRI in evaluation of asbestos related thoracic diseases - preliminary

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D. Nespor, K. Bartusek and Z. Dokoupil

Medicine and Biology, 51, 2093-2099. [9] Hayes, C.E., Edelstein, W.A., Schenck, J.F., Muller, O.M., Eash, M.J. (1985). An efficient, highly homogeneous radiofrequency coil for whole-body NMR imaging at 1.5T. Journal of Magnetic Resonance, 64, 622-628. [10] Baertlein, B.A., Ozbay, O., Ibrahim, T., Lee, R., Yu, Y., Kangarlu, A., Robitaille, P.M.L. (2000). The theoretical model for an MRI radiofrequency resonator. IEEE Transactions on Biomedical Engineering, 47, 535-546. [11] Vaughan, T., DelaBarre, L., Snyder, C., Tian, J

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M. Jaskólska, Z. Adamiak, Y. Zhalniarovich, P. Holak and P. Przyborowska

whole body experiments. In: Grant DM, Hardis RK (eds) Encyclopedia in NMR, 6th ed., West Sussex: John Wiley and Sons, pp 4996-5004. Bushberg JT (2002) Nuclear magnetic resonance. The essential physics of medical imaging. 2nd ed., Lippincott, Philadelphia, PA, pp 373-467. Busoni V, Denoix JM (2001) Ultrasonography of the podotrochlear apparatus in the horse using a transcuneal approach: technique and reference images. Vet Radiol Ultrasound 42: 534-540. Busoni V, Heimann M, Trenteseaux J, Snaps F, Dondelinger RF (2005

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Janez Podobnik, Igor Kocijancic, Viljem Kovac and Igor Sersa

References Hmeljak J, Cör A. Presence and role of Simian Virus 40 (SV40) in malignant pleural mesothelioma. Radiol Oncol 2009; 54: 9-16. Weber MA, Bock M, Plathow C, Wasser K, Fink C, Zuna I, et al. Asbestosrelated pleural disease: value of dedicated magnetic resonance imaging techniques. Invest Radiol 2004; 39: 554-64. Wang ZJ, Reddy GP, Gotway MB, Higgins CB, Jablons DM, Ramaswamy M, et al. Malignant pleural mesothelioma: evaluation with CT, MR imaging, and PET. Radiographics

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P. Hnilicová, M. Bittšanský and D. Dobrota

in transverse relaxation rates in the cerebral cortex. American Journal of Neuroradiology, 22 (9), 1732-1737. [4] Fanea, L., Sfrangeu, S.A. (2011). Relaxation times mapping using magnetic resonance imaging. Romanian Reports in Physics, 63 (2), 456-464. [5] Kumar, R., Delshad, S., Woo, M.A., Macey, P.M., Harper, R.M. (2012). Age-related regional brain T2-relaxation changes in healthy adults. Journal of Magnetic Resonance Imaging, 35 (2), 300-308. [6] Deoni, S.C.L., Peters, T.M., Rutt, B.K. (2005). Highresolution T1 and

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Jytte Banner, Christian Bjerre Høyer, Martin Roest Christensen, Alexandra Gheorghe, Anne Bugge, Gyda Lolk Ottesen, Lene Warner Thorup Boel, Jørgen Lange Thomsen, Line Kruckow and Christina Jacobsen

Abstract

Background: Forensic autopsy strategies may improve differential diagnostics both post-mortem and ante-mortem and aid in clinical settings concerning preventive efforts for premature mortality. Excess mortality and reduced life expectancy affect persons with severe mental illnesses (SMI) for multi-faceted reasons that remain controversial. Somatic conditions, medical treatment and lifestyle diseases, which are primarily examined in the living, contribute to premature deaths. The underlying pathophysiological mechanisms are unclear, though, and the benefits of a focused, standardised autopsy remain unproven. We have developed and implemented an optimised molecular–biological autopsy for deceased persons with SMI. Our aim is to map the occurrence of 1) somatic diseases and organ changes; 2) metabolic syndrome; 3) use and abuse of alcohol, pharmaceuticals and psychoactive substances; 4) pharmacokinetic and pharmacodynamic factors in the metabolism of pharmaceuticals; and 5) genetic variations (acquired and/or congenital) in sudden cardiac death. Additionally, we hope to contribute to diagnostic treatments and preventive measures to benefit those living with SMI. Methods: SURVIVE: let the dead help the living is a prospective, autopsy-based study on 500 deceased persons with SMI subjected to forensic autopsies under the Danish Act on Forensic Inquests and Autopsy. The autopsies followed an extended, standardised autopsy protocol comprised of whole-body computed tomography scanning, magnetic resonance imaging of the heart and brain and an extended forensic autopsy, including a wide panel of analyses (toxicology, microbiology, genetics, histology and biochemical analysis). Additionally, post-mortem data were linked to ante-mortem health data extracted from Danish national health registers.

Discussion: The SURVIVE autopsy procedure, including tissue sampling and bio banking, has been shown to be effective. We expect that the SURVIVE study will provide unique opportunities to unravel the mechanisms and causes of premature death in persons with SMI. We also expect that identifying prognostic biomarkers for comorbidities will contribute to prevention of premature deaths and comorbidities in persons with SMI.

Open access

Eun-Ha Moon, Seok Tae Lim, Yeon-Hee Han, Young Jin Jeong, Yun-Hee Kang, Hwan-Jeong Jeong and Myung-Hee Sohn

, clinical examination, US, and MR imaging in preoperative assessment of breast cancer. Radiology 2004; 233: 830-49. 11. Winnekendonk G, Krug B, Warm M, Gohring UJ, Mallmann P, Lackner K. Diagnostic value of preoperative contrast-enhanced MR imaging of the breast. Rofo 2004; 176: 688-93. 12. Antoch G, Vogt FM, Freudenberg LS, Nazaradeh F, Goehde SC, Barkhausen J, et al. Whole-body dual-modality PET/CTand whole-body MRI for tumor staging in oncology JAMA 2003; 290: 3199-206. 13. Czernin J, Allen-Auerbach M

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Slavica Shubeska-Stratrova, Snezana Markovik-Temelkova and Goran Petrovski

, et al. Magnetic-resonance imaging used for determining fat distribution in obesity and diabetes. Am J Clin Nutr 1991; 54(4): 623-627. 16. Heyward VH. Practical body composition assessment for children, adults, and older adults. Int J Sport Nutr 1998; 8(3): 285-307. 17. Hunter HL and NagyTR. Body composition in a seasonal model of obesity: longitudinal measures and validation of DXA. Obes Res 2002; 10: 1180-1187. 18. van der Kooy K, Leenen R, Seidell JC, et al. Waist-hip ratio is a poor predictor of changes in visceral