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of the organism [ 4 ]. Toxicity and primary or secondary resistance are common problems of conventional chemotherapy. Thus, studies focusing on finding biomarkers to predict the response of the patients and tumors to the drugs used are an important part of precision medicine [ 5 ]. The twist transcription factor, encoded by the TWIST1 gene ( TWIST1 ; OMIM* 601622) is a member of the basic helix loop helix transcription factor family and has an important role in cell lineage determination and differentiation as an essential regulator during embryogenesis

). Woodhead Publishing India (New Delhi). [6] Jones, J. E. Haddad, G. N. and Sutton, J.N. (1971). Tensile Characteristics of Twisted Continuous-Filament Glass Yarns. Textile Research Journal. Vol. 41, Issue 11, pp. 900- 904. [7] Kilby, W. F. (1964). The Mechanical Properties of Twisted Continuous Filament Yarns. The Journal of the Textile Institute, Volume 55, Issue 12, pp. T589-T632. [8] Treloar, L. R. G. and Riding, G. A. (1963). Theory of Stress-Strain Properties of Continuous-Filament Yarns. The Journal of the Textile Institute, Volume 54, Issue 4, pp.T156-T170. [9

References 1. A shkavandi ZJ, Najvani AD, Tadbir AA, Pardis S, Ranjbar MA, Ashraf MJ. MCM3 as a novel diagnostic marker in benign and malignant salivary gland tumors. Asian Pac J Cancer Prev. 2013;14:3479-82. 2. Jaafari-Ashkavandi Z, Ashraf MJ, Moshaverinia M. Salivary gland tumors: A clinicopathologic study of 366 cases in Southern Iran. Asian Pac J Cancer Prev. 2013;14:27-30. 3. Kwok WK, Ling MT, Lee TW, Lau TC, Zhou C, Zhang X, Chua CW, Chan KW, Chan FL, Glackin C, Wong YC, Wang X. Upregulation of Twist in prostate cancer and its implication as a therapeutic

. The Journal of The Textile Institute. 104(12), 1284-1291. [4] Hajiani, F., Ghareaghaji, A. A., Jeddi, A. A. A., Amirshahi, S. H., Mazaheri, F. (2014). Wicking properties of polyamide 66 twisted nanofiber yarn by tracing the color alteration in yarn structure. Fibers & Polymers, 15(9), 1966-1976. [5] Houshyar,S., Padhye, R., Nayak, R.(2017). Effect of Moisture-wicking Materials on the Physical and Thermo-physiological Comfort Properties of Firefighters’ Protective Clothing. Fibers and Polymers, 18(2): 383-389. [6] Kumar,P., Sinha,S.K., Ghosh, S.(2016). Estimation of

Abstract

The research of railway track surfaces is aimed at improving the quality of railway infrastructure and providing the chance of improving the safety of driving. Therefore, it is advisable to constantly monitor track surface, but the research itself is not innovative because it is based on a known procedure. The crucial element are the techniques that allow to delve into the sources of problems. The aim of the article is to use the selected instruments of quality management to analyze the causes of track twist at high (180 km/h) speed of driving. The analysis of the causes of track twist was done on the basis of results from the measurement of one kilometer track section of the Krakow Glowny - Medyka route, which was made by using the TEC measuring device in April 2018. It was inferred that it is impossible to reach 180 km/h without track twist. In order to identify the causes of track twist it was proposed to use the selected sequence of quality management instruments, i.e.: brainstorming, Ishikawa diagram and the 5Why method. The identified causes of track twist include the abrasion of rail, scratches and exploitation point. The analysis and conclusions drawn from it may be useful in the analysis of other problems in railway transport as well as production and service industries.

control of a marine current turbine driven permanent magnet synchronous generator In: Proceedings of the 2009 IEEE International Electric Machines and Drives Conference, Miami, FL, USA, 3-6 May 2009. Gonzales, T., Moreno, A. and Fridman, L. (2012). Variable gain super-twisting sliding mode control. IEEE Transactions on Automatic Control, 57(8), pp. 2100-2105. Lascu, C. and Blaabjerg, F. (2014). Super-twisting slidingmode direct torque control of induction machine drives. In: Proceedings of the 2014 IEEE Energy Conversion Congress and Exposition (ECCE), Pittsburgh, PA

Mechanical Engineers, pp. 487-496, 2005,. 4. B.T. An, W.J. Han and Z.Q Wang, “Experience Research on Mechanism of Twisted Blades Reducing Losses”, Thermal Energy Power Engineering, no. 15, pp. 498-501, 2000,. 5. Z.M. Feng, W.A. Hang and J.J. Zhong, “Experimental Study on Post-load Positive Bending Cascade Aerodynamic Performance”, Experimental Fluid Mechanics, no. 23, pp 6. H.W. Lu, X.X. Kan and J.J. Zhong, etc. :Analysis of the Flow Structure in Positive Bending Compressor Stationary Guide Blade Passageway”, Engineering Thermophysics Newspaper, no. 34, pp. 1828-1832, 2013

) - Problems and solutions in mathematics, World Scientific, 1998. [16] J. B. M. Meusiner - Mémoire sur la courbure des surfaces, Mém. des savans étrangers 10 (read in 1776, print 1785), 477-510. [17] W. H. Meeks III and M. Weber - Bending the helicoid, Math. Ann. 339(2007), 783-798. [18] B. O'Neill - Semi-Riemannian geometry with applications to relativity, Academic Press, San Diego, 1983. [19] V. Pambuccian - Euclidean geometry problems rephrased in terms of midpoints and pointreections, Elem. Math. 60(2005) 19-24. [20] R. Ponge and H. Reckziegel - Twisted products in

., V. Le, M. Ghanes, J.-P. Barbot, G. Santomenna. Observateur à mode glissant d’ordre 2 pour la machine asynchrone sans capteur mécanique. In Author Manuscript, Published in CIFA, Nancy, France, 2010. 26. Salgado, I., I. Chairez, J. Moreno, L. Fridman, A. Poznyak. Generalized Super- Twisting Observer for Non Linear Systems. - In: Preprints of the 18th IFAC World Congress Milano (Italy), 28 August-2 September 2011, pp. 14353-14358. 27. Rabhi, A., N. K. M’Sirdi, M. Ouladsine, L. Fridman. Estimation of Road Profile Using Second Order Sliding Mode Observer. In Authour

Cosmopolitanism and Forgiveness. By Jacques Derrida. London and New York: Routledge, 2001. vii-xii. De Quincey, Thomas. Confessions of an English Opium-Eater . Champaign, Ill: Project Gutenberg, n.d. eBook Collection (EBSCOhost) . Web. 4 Sept. 2013. Derrida, Jacques. Adieu to Emmanuel Levinas . Trans. Pascale-Anne Brault and Michael Nass. Stanford: Stanford UP, 1997. Derrida, Jacques. On Cosmopolitanism and Forgiveness. Trans. Mark Dooley and Michael Hughes. London and New York: Routledge, 2001. Print. Doyle, Arthur Conan. The Man with the Twisted Lip . The Complete