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Reversed phase HPLC for strontium ranelate: Method development and validation applying experimental design

, K. R. Teja, K. Chitra and C. U. M. Reddy, Development and validation of RP-HPLC method for the estimation of strontium ranelate in sachet, Int. J. Pharm. Bio. Sci. 2 (2011) 258–263. 4. B. R. C. S. Reddy and N. V. B Rao, A validated stability indicating RP-HPLC method for the determination of strontium ranelate a dual acting bone agent in bulk and sachet dosage form, Rasayan J. Chem. 7 (2014) 20–27. 5. H. L. Yin and Y. J. Xu, RP-HPLC determination of strontium ranelate and its related substances, Chin. J. Pharm. Anal. 2 (2009) 330

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Development and Validation of an UV-Spectrophotometric Method for the Assay of Strontium Ranelate and HPLC Stability Testing from Bulk and Pharmaceutical Dosage Form

References 1. Reginster JY, Brandi ML, Cannata-Andía J et al - The position of strontium ranelate in today’s management of osteoporosis. Osteoporos Int. 2015;26:1667-71 2. EMEA, European Medicines Agency, Osseor, Scientific Discussion, London 2005; ; last access date: May 10, 2018 3. Mythili K, Gayatri S, Kumar EM, et al - Development and validation of UV spectrophotometric method for the estimation of strontium ranelate in sachet

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Treatment of Osteoporosis

postmenopausal women with osteoporosis. New Engl J Med 1990;322:802-9. Kleerekoper M, Peterson EL, Nelson DA, Phillips E, Schork MA, Tilley BC, Parfitt AM. A randomized trial of sodium fluoride as a treatment for postmenopausal osteoporosis. Osteoporosis Int 1991;1:155-61. Meunier PJ, Roux C, Seeman E, Ortolani S, Badurski JE, Spector TD, Cannata J, Balogh A, Lemmel EM, Pors-Nielsen S, Rizzoli R, Genant HK, Reginster JY. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal

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Evaluation of Densitometric and Geometric Parameters of Tibiotarsal Bones in Turkeys

of commercial poultry species. Poult Sci 1994, 73 , 897-903. 12. Lynch M., Thorp B., Whitehead C.: Avian tibia dyschondroplasia as a cause of bone deformity. Avian Pathol 1992, 21 , 275-285. 13. Poulos P.W.: Tibial dyschondroplasia (osteochondrosis) in the turkey. A morphologic investigation. Acta Radiol Suppl 1978, 358 , 197-227. 14. Radzki R.P., Bieńko M., Filip R.: Influence of strontium ranelate on mineral and mechanical properties of the femur in orchidectomized rats. Medycyna Wet 2007, 63 , 1630

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Therapeutical Approach of Osteoporosis — a Multidisciplinary Issue

, Moffett AH, et al. Denosumab in postmenopausal women with low bone mineral density. N Engl J Med. 2006;354(8):821-31. 19. Blake GM, Fogelman I. Long-term effect of strontium ranelate treatment on BMD. J Bone Miner Res. 2005;20(11):1901-4.

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Zinc asparaginate supplementation induces redistribution of toxic trace elements in rat tissues and organs

zinc complex of L-carnosine for medical use. Biochemistry Mosc 65 : 817–823. Nriagu JO. (1996). A history of global metal pollution. Science 272 :223. Oliveira DM, Lacava ZG, Lima EC, Morais PC, Tedesco AC. (2006). Zinc phthalocyanine/magnetic fluid complex: a promising dual nanostructured system for cancer treatment. J Nanosci Nanotechnol 6 : 2432–2437. Oliveira JP, Querido W, Caldas RJ, Campos AP, Abraçado LG, Farina M. (2012). Strontium is incorporated in different levels into bones and teeth of rats treated with strontium ranelate

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Post-Effort Changes in Activity of Traditional Diagnostic Enzymatic Markers in Football Players’ Blood / Promene U Aktivnostima Tradicionalnih Dijagnostičkih Enzimskih Markera U Krvi Fudbalera Posle Fizičkog Naprezanja

function of liver in patients with diabetes mellitus. Bratisl Lek Listy 2005; 106: 266-9. 30. Iida T, Harada T, Ishizaki F, Nitta Y, Aoi S, Ikeda H, et al. Changes in bone mineral density and metabolism in women: evaluation of bodily characteristics, bone metabolic markers and bone mineral density. Hiroshima J Med Sci 2013; 62: 49-53. 31. Bayhan I, Dogan NU, Ozaksit G, Uygur D, Ugurlu N, Ugur M. Effect of strontium ranelate on serum leptin and bone turnover markers in women with established postmenopausal osteoporosis. J Reprod Med 2013

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Evaluation of Densitometric and Geometric Parameters of the Femur in 14-Month-Old Ostriches Depending on Sex with the Use of Computed Tomography

. Kawka M., Horbańczuk J.O., Sacharczuk M., Zięba G., Łukaszewicz M., Jaszczak K., Parada R.: Genetic characteristics of the ostrich population using molecular methods. Poult Sci 2007, 86 , 277-281. 16. Poławska E., Marchewka J., Cooper R.G., Sartowska K., Pomianowski J., Jóźwik A., Strzałkowska N., Horbańczuk J.O.: The ostrich meat - an updated review. II. Nutritive value. Anim Sci Pap Rep 2011, 29 , 89 -97. 17. Radzki R.P., Bieńko M., Filip R.: Influence of strontium ranelate on mineral and mechanical properties of the femur in

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Osteoporosis: Therapeutic Options

. Parathyroid hormone for the treatment of osteoporosis: a systematic review. CMAJ 2006;175:52-9. 50. European Medicines Agency. PRAC recommends suspending use of Protelos / Osseor (strontium ranelate) Recommendation by PRAC to be considered by CHMP for fi nal opinion. Press release 10 January 2014; p.1-2.

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Patterns in the Diagnosis and Treatment of Osteoporosis in Men: A Questionnaire-based Survey in Central and Eastern European Countries

(Prolia): Treatment to increase bone mass in men with osteoporosis at high risk for fracture; or who have failed or are intolerant to other available osteoporosis therapy [Internet]. 21. Cusano NE, Costa AG, Silva BC, Bilezikian JP. Therapy of osteoporosis in men with teriparatide. J Osteoporos 2011:463675. 22. Hiligsmann M, Ben Sedrine W, Bruyère O, Reginster JY. Cost-effectiveness of strontium ranelate in the treatment of male osteoporosis. Osteoporos Int 2013, 24:2291-2300. 23. Borst SE, Yarrow JF. Injection of testosterone may be safer and more

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