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Izabela Deperasińska, Patrycja Schulz and Andrzej K. Siwicki

Introduction Salmonid alphavirus (SAV) is an enveloped, single-stranded, positive-sense RNA virus with a ~12 kb genome, belonging to the family Togaviridae , genus Alphavirus . It is known to be a serious pathogen for Atlantic salmon ( Salmo salar ) and rainbow trout ( Oncorhynchus mykiss ) in Europe. SAV is responsible for pancreas disease (PD) affecting Atlantic salmon, first reported in Scotland in 1976 ( 26 ). A similar disease, termed “sleeping disease” (SD) and affecting rainbow trout has been described and reported in France ( 6 ). A comparative

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Carmen Ardelean, Daniel Lighezan, Raluca Morar, Sorin Pescariu and Stefan Mihăicuță

with Sleep Apnea Syndrome as predictor for coronary-vascular comorbidities. Pneumologia . 2016;65(1):14–8. 12. Randerath W, Verbraecken J, Andreas S, Arzt M, Bloch KE, Brack T, et al. Definition, discrimination, diagnosis and treatment of central breathing disturbances during sleep. European Respiratory Journal . 2017;49(1). Available from: doi: 10.1183/13993003.00959-2016. 13. Reuter H, Herkenrath S, Treml M, Halbach M, Steven D, Frank K, et al. Sleep-disordered breathing in patients with cardiovascular diseases cannot be detected by ESS, STOP

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Ewa Borzym, Joanna Maj-Paluch, Magdalena Stachnik, Marek Matras and Michał Reichert

References 1. Bergmann S.M., Castric J., Brémont M., Riebe R., Fichtner D.: Detection of sleeping disease virus (SDV) in Germany. EAFP 12 th International Conference, Book of Abstracts, Copenhagen, 2005, 0150. 2. Boucher P., Castric J., Baudin-Laurencin F.: Observation of virus-like particles in rainbow trout Oncorhynchus mykiss infected with sleeping disease virulent material. Bull Eur Assoc Fish Pathol 1994, 14, 215216. 3. Castric J., Baudin-Laurencin F., Brémont M., Jeffroy J., Le Van A., Béarzotti M.: Isolation of the virus responsible for sleeping

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Diana Cristina Protasiewicz, Adina Popa, Maria-Magdalena Roşu, Adela-Gabriela Firănescu, Simona Georgiana Popa and Maria Moța

C. Impact of obstructive sleep apnoea on type 2 diabetes and vice versa. European Endocrinology 9: 107-109, 2013. 9. Franklin KA, Lindberg E . Obstructive sleep apnea is a common disorder in the population - a review on the epidemiology of sleep apnea. J Thorac Dis 7: 1311-1322, 2015. 10. Adams RJ, Appleton SL, Vakulin A et al. Association of kidney disease with obstructive sleep apnea in a population study of men. Sleep 2016, pii: sp-00240-16, 2016. [Epub ahead of print] 11. Zhang P, Zhang R, Zhao F et al. The prevalence and

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Parima Hirunwiwatkul, Vilavun Puangsricharern, Nisa Sothornwit, Prin Rojana Pongpun, Jeerawat Sawatdiwithayayong and Prakobkiat Hirunwiwatkul

References 1. Flemons WW. Clinical practice. Obstructive sleep apnea. N Engl J Med. 2002; 347:498-504. 2. Horchover RL. Oral appliances of the treatment of obstructive sleep apnea. Asian Biomed. 2007; 1:49-52. 3. Hirunwiwatkul P. Efficacy and adverse effects of Xanthane nasal solution as treatment of primary snoring. Asian Biomed. 2008; 2:189-93. 4. McNab AA. Reversal of floppy eyelid syndrome with treatment of obstructive sleep apnoea. Clin Experiment Ophthalmol. 2000; 28

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Jeler Elena-Corina

al. Obstructive sleep apnoea syndrome. Nature Reviews Disease Primers. (2015). 1. 10.1038/nrdp.2015.24. 5. Susheel P. Patil, et al. “Adult Obstructive Sleep Apnea Pathophysiology and Diagnosis” Chest. 2007 Jul; 132(1): 325. 6. Fogel RB, et al. “The effect of sleep onset on upper airway muscle activity in patients with sleep apnoea versus controls.” J Physiol. 2005;564:549–562. 7. Strohl KP. “Upper airway muscles of respiration.”Am Rev Respir Dis, 1981; 124: 211–213. 8. Fogel RB, et al. Sleep. 2: pathophysiology of obstructive sleep apnoea

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Elena Patrascu and Claudiu Manea

. Obstructive sleep apnea and cardiovascular disease. JACC . 2003;41(9):1429-37. DOI: 10.1016/S0735-1097(03)00184-0. 8. Shahar E, Whitney CW, Redline S, Lee ET, Newman AB, Nieto FJ, et al. Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study. Am J Respir Crit Care Med . 2001;163(1):19-25. 9. Svatikova A, Wolk R, Gami AS, Pohanka M, Somers VK. Interactions between obstructive sleep apnea and the metabolic syndrome. Curr Diab Rep . 2005;5(1):53-8. 10. Engleman H, Douglas N. Sleep · 4: Sleepiness

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Bei Wang

References 1. Cardiology Society in Chinese Medical Association and Sleep Breath Disorder Group of Respiratory Diseases Society in Chinese Medical Association, expert consensus on sleep apnea and cardiovascular diseases. Chin J Intern Med 2009;48:1059-67. 2. Budhiraja R, Budhiraja P, Quan SF. Sleep-disordered breathing and cardiovascular disorders. Respir Care 2010;55:1322-32. 3. Marin JM, Carrizo SJ, Vicente E, Agusti AG. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or

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Ralph Panos and William Eschenbacher

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Ionescu Ana-Maria, Dumitrescu Cătălin, Copaci Carmen, Iliescu Dan, Hangan Tony and Bobe Alexandru

. InAcoustics, Speech, and Signal Processing, 1992. ICASSP-92., 1992 IEEE International Conference on 1992 Mar 23 (Vol. 5, pp. 177-180). IEEE.. 5. Colrain I. M., (2005). The K-complex : A 7-decade history. Sleep Med, 28, pp. 255-273. [CrossRef] [PubMed] 6. Bliwise DL. Sleep disorders in Alzheimer’s disease and other dementias. Clinical cornerstone. 2004 Jan 1;6(1):S16-28. 7. Bastuji H, García-Larrea L. Evoked potentials as a tool for the investigation of human sleep. Sleep medicine reviews. 1999 Mar 1;3(1):23-45. 8. Ehrhart J, Ehrhart M, Muzet A