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Ada Stelmakienė, Kristina Ramanauskienė and Vitalis Briedis

the human skin in vitro, Evid. Based Compl. Altern. Med. (2013) Article ID 958717; DOI: 10.1155/2013/958717. 10. T. Kezutyte, T. Drevinskas, A. Maruska, R. Rimdeika and V. Briedis, Study of tolnaftate release from fatty acids containing ointment and penetration into human skin ex vivo, Acta Pol. Pharm. 68 (2011) 965-973. 11. R.-K. Chang, A. Raw, R. Lionberger and L. Yu, Generic development of topical dermatologic products: Formulation development, process development, and testing of topical dermatologic products, AAPS J. 15 (2013) 41

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Santo Scalia, Valentina Trotta and Anna Bianchi

. Der Marderosian, G. Hanson, T. Medwick, N. Popovich, R. Schnaare, J. Schwartz and H. White), Lippincott Williams & Wilkins, Baltimore 2000, pp. 836-848. 8. S. E. Belo, L. R. Gaspar, P. M. B. G. Maia Campos and J.-P. Marty, Skin penetration of epigallocathechin-3-gallate and quercetin from green tea and ginkgo biloba extracts vehiculated in cosmetic formulations, Skin Pharmacol. Physiol. 22 (2009) 299-304; DOI: 10.1159/000241299. 9. W. Wisuitiprot, A. Somsiri, K. Ingkaninan and N. Waranuch, In vitro human skin penetration and cutaneous

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Dorota Wojcik-Pastuszka, Anna Lisik, Maria Twarda, Ryszard Berkowski and Witold Musial

arrangements of Ph.Eur./USP extraction cells during dissolution tests of calcium dobesilate in hydrogel formulation. Curr. Issues Pharm. Med. Sci., 28, 136, 2015. 24. Morimoto N. et al.: The Rapid Inactivation of Porcine Skin by Applying High Hydrostatic Pressure without Damaging the Extracellular Matrix. BioMed Res. Int., 2015, Article ID 587247, 2015. 25. Reddy D. N. et al.: Design, development and characterization of clopidogrel bisulfate transdermal drug delivery system - Asian J. Pharm. Clin. Res., 8, 277, 2015. 26. Rota R

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Othman A. Al Hanbali, Haji Muhammad Shoaib Khan, Muhammad Sarfraz, Mosab Arafat, Shakeel Ijaz and Abdul Hameed

carriers, Glob. Drug Therap . 2 (2016) 1–2; https://doi.org/10.15761/GDT.1000109 20. J. Suksaereeab, L. Charoenchaib, F. Madakab, C. Montonb, A. Sakunpak, T. Charoonratana and W. Zingiber, Cassumunar blended patches for skin application: Formulation, physicochemical properties, and in vitro studies, Asian J. Pharm. Sci . 10 (2015) 341–349; https://doi.org/10.1016/j.ajps.2015.03.001 21. A. C. Willams and B. W. Barry, Penetration enhancers, Adv. Drug. Del. Rev . 56 (2004) 603–618. 22. S. D. Saoji, S. C. Atram, P. W. Dhore, P. S. Deole, N. A. Raut and V. S

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Aly H. Nada, Abdelazim A. Zaghloul, Mohsen M. Hedaya and Ibrahim S. Khattab

and P. Santi, Synthesis, hydrolysis, and skin retention of amino acid esters of alpha-tocopherol, J. Pharm. Sci. 98 (2009) 2364-2376; DOI: 10.1002/jps.21608. 10. E. S. Krol, K. A. Kramer-Stickland and D. C. Liebler, Photoprotective actions of topically applied vitamin E, Drug Met. Rev. 32 (2000) 413-420; DOI: 101081DMR100102343. 11. M. Rangarajan and J. L. Zatz, Effect of formulation on the delivery and metabolism of alpha-tocopheryl acetate, J. Cosmet. Sci. 52 (2001) 225-236; PMID 11479655. 12. A. C. Williams and B

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Evren Algin Yapar, Özge Ýnal and M. Sedef Erdal

skin fibroblasts from reactive oxygen species induced necrosis, J. Drugs Dermatol. 10 (2011) 1096-1101. 7. A. Rasheed, S. N. Shama, J. M. Joy, B. S. Reddy and C. Roja, Formulation and evaluation of herbal anti-acne moisturizer, Pak. J. Pharm. Sci. 25 (2012) 867-870. 8. F. Casetti, U. Wölfle, W. Gehring and C. M. Schempp, Dermocosmetics for dry skin: a new role for botanical extracts, Skin Pharmacol. Physiol. 24 (2011) 289-293; DOI: 10.1159/000329214. 9. S. Ulusoy, G. Bosgelmez-Tinaz and H. Seçilmis

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Kalpesh C. Ashara and Ketan V. Shah

Sci 2014;6(1):691-99. 8. Hamishehkar H, Khoshbakht M, Jouyban A, et al. The relationship between solubility and transdermal absorption of Tadalafil. Adv Pharm Bull 2015;3(2):411-7. 9. Srinivas P, Sreeja K. Formulation and evaluation of voriconazole loaded nanosponges for oral and topical delivery. Int J Drug Dev & Res 2013;5(1):55-69. 10. Patel NA, Patel NJ, Patel RP. Comparative development and evaluation of topical gel and cream formulations of psoralen. Drug Discov Ther 2009;3(5):234-42. 11. Andonova VY, Georgiev GS, Georgieva VT, et al

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Sanjula Baboota, Faiyaz Shakeel, Alka Ahuja, Javed Ali and Sheikh Shafiq

References E. Escibano, A. C. Calpena, J. Queralt, R. Obach and J. Domenech, Assessment of diclofenac permeation with different formulations: anti-inflammatory study of a selected formula, Eur. J. Pharm. Sci. 19 (2003) 203--210; DOI: 10.1016/S0928-0987(03)00103-9. Gaurel, A. M. Martel and J. Castaner, Celecoxib, anti-inflammatory, cyclo-oxygenase-2 inhibitor, Drug Future 22 (1997) 711--714. K. A. Walters, Penetration Enhancers and their Use in Transdermal Therapeutic Systems

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Nataša Z. Bubić Pajić, Marija N. Todosijević, Gordana M. Vuleta, Nebojša D. Cekić, Vladimir D. Dobričić, Sonja R. Vučen, Bojan R. Čalija, Milica Ž. Lukić, Tanja M. Ilić and Snežana D. Savić

.colsurfb.2014.05.041 12. M. M. Abdellatif, I. A. Khalil and M. A. F. Khalil, Sertaconazole nitrate loaded nanovesicular systems for targeting skin fungal infection: in-vitro, ex-vivo and in-vivo evaluation, Int. J. Pharm. 527 (2017) 1-11; https://doi.org/10.1016/j.ijpharm.2017.05.029 13. S. Güngör, M. S. Erdal and B. Aksu, New formulation strategies in topical antifungal therapy, JCDSA. 3 (2013) 56-65; http://dx.doi.org/10.4236/jcdsa.2013.31A009 14. G. Bhatia, Y. Zhou and A. K. Banga, Adapalene microemulsion for transfollicular

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Ümit Gönüllü, Melike Üner, Gülgün Yener, Ecem Fatma Karaman and Zeynep Aydoğmuş

. Biotechnol. 148 (2010) 24-30; DOI: 10.1016/j.jbiotec.2010.01.001. 11. V. Sanna, G. Caria and A. Mariani, Eff ect of lipid nanoparticles containing fa_ y alcohols having diff erent chain length on the ex vivo skin permeability of econazole nitrate, Powder Technol. 201 (2010) 32-36; DOI: 10.1016/j.powtec.2010.02.035. 12. E. B. Souto, C. Anselmi, M. Centini and R. H. Muller, Preparation and characterization of n-dodecyl- ferulate-loaded solid lipid nanoparticles (SLNR), Int. J. Pharm. 295 (2005) 261-268; DOI: 10.1016/j.ij pharm.2005