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Violeta Dinesch, Mihail Dinesch, Ileana Voichita Sirbu, Cosmin Macarie, Bogdan Vasile Halatiu and Mircea Buruian

References 1. Bønaa K, Mannsverk J, Wiseth R, et al. - Drug-eluting or bare-metal stents for coronary artery disease. N Engl J Med. 2016;375:1242-1252. 2. Kaneko H, Yajima J, Oikawa Y, et al. - Long-term incidence and prognostic factors of progression of new coronary lesions in Japanese coronary artery disease patients after percutaneous coronary intervention. Heart Vessels. 2014;29:437-442. 3. Park MW, Seung KB, Kim PJ, et al. - Long-term percutaneous coronary intervention rates and associated independent

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Sonja Stojanović, Bojana Stamenković, Jovan Nedović, Tatjana Jevtović-Stoimenov and Dušica Pavlović

-7. 4. Angwin J, Heald G, Lloyd A, Howland K, Davy M and James MF. Reliability and sensitivity of Joint Space Measurements in Hand Radiographs Using Computerized Image Analysis. J Rheumatol 2001; 28:1825-36. 5. Larsen A. How to apply Larsen score in evaluating radiographs of rheumatoid arthritis in long-term studies. J Rheumatol 1995; 22:1974-5. 6. Van Tuyl LHD, Voskuyl AE, Boers M, Geusens P, Landewé RMB, Dijkmans BAC et al. Baseline RANKL: OPG ratio and markers of bone and cartilage degradation predict annual radiological progression over 11 years in

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Norimitsu Kasahara, Hisao Imai, Kyoichi Kaira, Keita Mori, Kazushige Wakuda, Akira Ono, Tetsuhiko Taira, Hirotsugu Kenmotsu, Hideyuki Harada, Tateaki Naito, Haruyasu Murakami, Masahiro Endo, Takashi Nakajima, Masanobu Yamada and Toshiaki Takahashi

-92. 9. Broglio KR, Berry DA. Detecting an overall survival benefit that is derived from progression-free survival. J Natl Cancer Inst 2009; 101: 1642-9. 10. Soria JC, Massard C, Le Chevalier T. Should progression-free survival be the primary measure of efficacy for advanced NSCLC therapy? Ann Oncol 2010; 21: 2324-32. 11. Reck M, von Pawel J, Zatloukal P, Ramlau R, Gorbounova V, Hirsh V, et al. Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil. J

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Desislava M. Bozhkova and Elena G. Poryazova-Markova

REFERENCES 1. Boyer B, Thiery J. Epithelium-mesenchyme interconversion as example of epithelial plasticity. Apmis 1993; 101: 257-68. 2. D’Souza-Schorey C. Disassembling adherens junctions: breaking up is hard to do. Trends Cell Biol 2005; 15: 19-26. 3. Hugo H, Ackland M, Blick T. Epithelial-mesenchymal and mesenchymal-epithelial transitions in carcinoma progression. J Cell Physiol 2007; 213: 374-83. 4. Kang Y, Massague J. Epithelial-mesenchymal transitions: twist in development and metastasis. Cell 2004; 118: 277-9. 5. Thiery J

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Ivan Jovanovic, Nevena Gajovic, Gordana Radosavljevic, Jelena Pantic, Nada Pejnovic, Nebojsa Arsenijevic and Miodrag L. Lukic

R, McFarland AP, Reynolds DA et al. A novel role for IL-22R1 as a driver of inflammation. Blood 2011; 117: 575-84. 61. Park O, Wang H, Weng H et al. In vivo consequences of liver-specific interleukin-22 expression in mice: implications for human liver disease progression. Hepatology 2011; 54: 252-61. 62. Riccardi C, Santoni A, Barlozzari T, Puccetti P, Herberman RB. In vivo natural reactivity of mice against tumour cells. Int J Cancer 1980; 25: 475-486. 63. Wiltrout RH, Herberman RB, Zhang SR et al. Role of organ-associated NK cells in decreased

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Alina Ramona Potra, Ina Maria Kacso, Ioana Cosmina Bondor and Mirela Gherman-Căprioară

. Macrophages in streptozotocin-induced diabetic nephropathy: potential role in renal fibrosis. Nephrol Dial Transplant 2004; 19(12):2987-96 12. Matsui H, Suzuki M, Tsukuda R, Iida K, Miyasaka M, Ikeda H. Expression of ICAM-1 on glomeruli is associated with progression of diabetic nephropathy in a genetically obese diabetic rat, Wistar fatty. Diabetes Res Clin Pract 1996; 32(1-2):1-9 13. Watanabe N, Shikata K, Shikata Y, Sarai K, Omori K, Kodera R, et al. Involvement of MAPKs in ICAM-1 expression in glomerular endothelial cells in diabetic

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Gilbert Umaye Adie, Aminat Adetayo-Balogun and Chidiebere Mmaduka Agudosi

Abstract

This study assessed the progression of Pb, Cd and Cr concentrations in plastic components (PCs) and printed wiring boards (PWBs) of 59 end-of-life (EoL) mobile phones (MPs) produced between 2000 and 2015 by two leading original equipment manufacturers (OEMs) patronized by Nigerians. This was done to study the behavior of OEMs in complying with some widely acceptable regulations. Metals in PCs and PWBs of MPs were extracted following EPA 3050B method and extracts were analyzed using atomic absorption spectrophotometry technique. Furthermore, Toxicity Characteristic Leaching Procedure (TCLP) test was conducted on selected samples to assess metal leachability in landfill conditions. Summary of results (mg/kg) for PCs and PWBs for MPs produced by OEM 1 and OEM 2 in brackets ranged thus: PCs, Pb: 5.00 –195 (LOD-1750), Cr: LOD-6050 (LOD-2170) and Cd: LOD-1.00 (LOD-5.75) while PWBs, Pb:129-9750 (5.00-12125), Cr: LOD-5488 (LOD-4000) and Cd: LOD-1.00 (0.25-1.00). There were no regular trends for all metals for both OEMs. Results suggest that a greater percentage of MPs produced till 2015 contained Pb and Cr higher than RoHS and TTLC limits. Furthermore, 50% of TCLP extracts contain Pb higher than EPA limit of 5 mg/L. Therefore, EoL MPs arising in Nigeria should be handled as hazardous materials.

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Nasta Tanić, Jelena Milašin, Tatjana Dramićanin, Maja Bošković, Miroslav Vukadinović, Verica Milošević and Nikola Tanić

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Francesco Montagnani, Greta Di Leonardo, Mariasimona Pino, Simona Perboni, Angela Ribecco and Luisa Fioretto

Introduction Angiogenesis is a critical step in colorectal cancer growth, progression and metastasization. The process of blood vessels formation involves many different molecules and pathways. Among these, the vascular endothelial growth factors (VEGFs) driven pathway is one of the most powerful and better studied.[ 1 ] VEGFs comprises a family of multiple growth factors that act through the activation of at least three different receptors.[ 2 ] In a landmark trial, the anti-VEGF-A monoclonal antibody bevacizumab improved progression-free survival (PFS

Open access

Florian Luca and Augustine O. Munagi

References 1. Cook, R.; Sharpe, D. - Sums of arithmetic progressions, Fibonacci Quart., 33 (1995), 218-221. 2. Goulden, I.P.; Jackson, D.M. - The enumeration of generalised alternating subsets with congruences, Discrete Math., 22 (1978), 99-104. 10.1016/0012-365X(78)90118-8 3. Munagi, A.O.; Shonhiwa, T. - On the partitions of a number into arithmetic progressions, J. Integer Seq., 11 (2008), Article 08.5.4, 10 pp. 4. Munagi, A.O. - Alternating subsets and permutations, Rocky Mountain J. Math., 40