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Dorota Link-Lenczowska and Tomasz Sacha

Wstęp Pierwotne włóknienie szpiku kostnego ( primary myelofibrosis – PMF) należy do nowotworów mieloproliferacyjnych bez chromosomu Filadelfia. Charakteryzuje się najbardziej niekorzystnym rokowaniem spośród nowotworów mieloproliferacyjnych [ 1 , 2 ]. Do jego oceny wykorzystywane są różne modele prognostyczne. System oceny punktowej stanowi wskazówkę dla decyzji dotyczących sposobów leczenia, obejmujących także allogeniczne przeszczepienie komórek macierzystych ( allogeneic hematopoietic stem cell transplantation – allo-HSCT). Do powszechnie stosowanych

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V. Grozeva and A. Kundurzhiev

peritoneal dialysis. Nephron, 2002;91(1), 94-102. 15. Yamamoto, T, Ozono K, Miyauchi A et al. Role of advanced glycation end products in adynamic bone disease in patients with diabetic nephropathy. Am J Kidney Dis, 2001;38(4), Suppl. 1 S161-S164. 16. London, G. Cardiovascular disease in end stage renal failure: role of calcium-phosphate disturbances and hyperparathyreoidism. J. Nephrol, 2002;15(2), 209-210. 17. Rao, D.S., M.S. Shih, R. Mohini. Effect of serum parathyroid hormone and bone marrow fibrosis on the response to erythropoietin in uremia. N. Engl

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Anna Snarska, Dominika Wysocka and Liliana Rytel

.M., Sadik N.A., Azzam M..: The therapeutic effects of bone marrow-derived mesenchymal stem cells and simvastatin in a rat model of liver fibrosis. Cell Biochem Biophys 2014, 68, 111–25. 12. Mundy G., Garrett R., Harris S., Chan J., Chen D., Rossini G., Boyce B., Zhao M., Gutierrez G.: Stimulation of bone formation in vitro and in rodents by statins. Science 1999, 286, 1946–1949. 13. Newman A., Clutterbuck R.D., Powles R.L., Chan J., Chen D., Rossini G., Boyce B., Zhao M., Gutierrez G.: Selective inhibition of primary acute myeloid leukaemia cell growth by

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Magdalena Kulus, Jakub Kulus, Maurycy Jankowski, Blanka Borowiec, Michal Jeseta, Dorota Bukowska, Klaus P. Brüssow, Bartosz Kempisty and Paweł Antosik

References 1. Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, Jones JM. Embryonic stem cell lines derived from human blastocysts. Science. 1998;282(5391):1145-1147; DOI:10.1126/SCIENCE.282.5391.1145. 2. Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends and future prospective. Biosci Rep. 2015;35(2); DOI:10.1042/BSR20150025. 3. Fortier LA, Nixon AJ, Williams J, Cable CS. Isolation and chondrocytic differentiation of equine bone marrow-derived mesenchymal stem cells. Am J Vet Res. 1998

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Maurycy Jankowski, Marta Dyszkiewicz-Konwińska, Joanna Budna, Sandra Knap, Artur Bryja, Sylwia Borys, Wiesława Kranc, Magdalena Magas, Michal Jeseta, Dorota Bukowska, Paweł Antosik, Klaus P. Brüssow, Marie Machatkova, Małgorzata Bruska, Michał Nowicki, Maciej Zabel and Bartosz Kempisty

. Regul. Homeost. Agents , vol. 31, no. 1, pp. 1-8, 2017. 46. Kranc, W. et al. , “Expression Profile of Genes Regulating Steroid Biosynthesis and Metabolism in Human Ovarian Granulosa Cells—A Primary Culture Approach,” Int. J. Mol. Sci. , vol. 18, no. 12, p. 2673, Dec. 2017. 47. Bhatia, S. et al. , “Late mortality in survivors of autologous hematopoietic-cell transplantation: report from the Bone Marrow Transplant Survivor Study,” Blood , vol. 105, no. 11, pp. 4215-4222, Jun. 2005. 48. Roura, S., Pujal, J.-M., Gálvez-Montón, C., and Bayes-Genis, A

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Nemanja Jovicic, Ilija Jeftic, Marina Miletic Kovacevic, Irena Tanaskovic, Nebojsa Arsenijevic, Miodrag L. Lukic and Nada Pejnovic

. 2011;25(8):2538-50. 32. Tang Y, Bian Z, Zhao L, Liu Y, Liang S, Wang Q, et al. Interleukin-17 exacerbates hepatic steatosis and inflammation in non-alcoholic fatty liver disease. Clin Exp Immunol. 2011;166(2):281-90. 33. Tan Z, Qian X, Jiang R, Liu Q, Wang Y, Chen C, et al. IL-17A plays a critical role in the pathogenesis of liver fibrosis through hepatic stellate cell activation. J Immunol. 2013;191(4):1835-44. 34. Lin SL, Castano AP, Nowlin BT, Lupher ML, Jr., Duffield JS. Bone marrow Ly6Chigh monocytes are selectively recruited to injured kidney

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Monica Marton-Popovici

Atherosclerotic Disease. N Engl J Med. 2017;377:1119-1131. doi: 10.1056/NEJMoa1707914. 12. Gyöngyösi M, Hemetsberger R, Wolbank S, et al. Delayed Recovery of Myocardial Blood Flow After Intracoronary Stem Cell Administration. Stem Cell Review and Reports. 2011;7:616-623. 13. Benedek I, Bucur O, Benedek T. Intracoronary Infusion of Mononuclear Bone Marrow-Derived Stem Cells is Associated with a Lower Plaque Burden After Four Years. J Atheroscler Thromb. 2014;21:217-229. 14. Gyöngyösi M, Hemetsberger R, Posa A, et al. Hypoxia

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István Benedek and Theodora Benedek

REFERENCES 1. Benedek T, Kovács I, Benedek I. Therapeutic Angiogenesis for Severely Ischemic Limbs — from Bench to Bedside in Acute Vascular Care. Journal of Cardiovascular Emergencies . 2017;3:160-171. 2. Tatu RF, Hurmuz M, Miu CA. ACL Primary Repair with Bone Marrow Stimulation and Growth Factors. A Review of Literature. Journal of Interdisciplinary Medicine . 2017; 2(S3):8-11. 3. Ojeh N, Pastar I, Tomic-Canic M, Stojadinovic O. Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications. Int J Mol Sci . 2015

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Razvan Gheorghita Mares, Goran Marinkovic, Ovidiu Simion Cotoi and Alexandru Schiopu

35. Hanna RN, Carlin LM, Hubbeling HG, Nackiewicz D, Green AM, Punt JA, et al. The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C- monocytes. Nat Immunol. 2011;12:778-85. DOI: 10.1038/ni.2063 36. Hilgendorf I, Gerhardt L, Tan TC, Winter C, Holderried TA, Chousterman BG, et al. Ly-6Chigh Monocytes Depend on Nr4a1 to Balance both Inflammatory and Reparative Phases in the Infarcted Myocardium. Circ Res. 2014. DOI: 10.1161/CIRCRESAHA.114.303204 37. van Amerongen MJ, Harmsen MC, van

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Güleser Saylam, Ömer Bayır, Salih Sinan Gültekin, Ferda Alparslan Pınarlı, Ünsal Han, Mehmet Hakan Korkmaz, Mehmet Eser Sancaktar, İlkan Tatar, Mustafa Fevzi Sargon and Emel Çadallı Tatar

the umbilical cord, adipose tissue, lung tissue, and bone marrow have been used as treatment agents for several diseases due to their capacity of tissue regeneration, trophic support, and modulation of the innate immune response. 11 , 12 Homing and engraftment of stem cells have been observed in damaged organs, such as the myocardium and kidney; those stem cells may increase function by reducing the levels of proinflammatory cytokines. 13 , 14 External radiation-induced salivary gland damage has been investigated in some studies. Lombaert et al . showed bone