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Stojan Potrc, Arpad Ivanecz, Vid Pivec, Urska Marolt, Sasa Rudolf, Bojan Iljevec and Tomaz Jagric

Introduction Resection of the head of pancreas remains a significant challenge for many pancreaticobiliary surgeon. Recently, better perioperative care, surgical technique, and better patient’s selection have undoubtedly led to better survival and have reduced the perioperative mortality. However, the high morbidity that accompanies these operations negates any positive long-term results in patients with otherwise poor prognosis that could have benefited from. The complications associated with PD procedures are well described. 1 , 2 These are usually of

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Danica Marković, Tatjana Jevtović-Stoimenov, Vladan Ćosić, Biljana Stošić, Vesna Dinić, Bojana Marković-Živković and Radmilo J. Janković

patients. J Am Coll Surg 2006; 203: 865–77. 20. D'Apuzzo MR, Pao AW, Novicoff WM, Browne JA. Age as an independent risk factor for postoperative morbidity and mortality after total joint arthroplasty in patients 90 years of age or older. J Arthroplasty 2014; 29: 477–80. 21. Lees MC, Merani S, Tauh K, Khadaroo RG. Perioperative factors predicting poor outcome in elderly patients following emergency general surgery: a multivariate regression analysis. Can J Surg 2015; 58: 312–7. 22. Hernandez AF, Whellan DJ, Stroud S, Sun JL, O'Connor CM, Jollis JG

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Benjamin Garlipp, Jens Schwalenberg, Daniela Adolf, Hans Lippert and Frank Meyer

References Jemal A, Siegel R, Ward E , et al.: Cancer statistics, 2006. CA Cancer J Clin 2006; 56: 106-30. Parkin DM, Bray F, Ferlay J , et al.: Global cancer statistics, 2002. CA Cancer J Clin 2005; 55: 74-108. Cunningham D, Allum WH, Stenning SP , et al.: Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. N Engl J Med 2006; 355: 11-20. Macdonald JS, Smalley SR, Benedetti J , et al.: Chemoradiotherapy after

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Marina Temelkovska-Stevanovska, Trajkovska Trajanka, Maja Mojsova-Mijovska and Marija Jovanovski-Srceva

JJ, Wenn RT, Sahota O, Moran CG. Effect of comorbidities and postoperative complications on mortality afterhip fracture in elderly people: prospective observational cohort study. BMJ 2005; 331: 1374. 6. Muhm M, Arend G, Ruffing T, Winkler H. Mortality and quality of life after proximal femur fracture-effect of time until surgery and reasons for delay. Eur J Trauma Emerg Surg 2013; 39: 267-275. 7. Fleisher LA, Beckman JA, Brown KA, Calkins H, et al . ACC/AHA 2007 Guidelineson Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery

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Tomaz Jagric, Bojan Ilijevec, Vaneja Velenik, Janja Ocvirk and Stojan Potrc

-point of the analysis was the 5-year overall survival and the median survival. Survival was defined as the time from the operation to the death from any cause. Secondary end-points of the study were the causes of death, prediction of response, prediction of the effect of perioperative and adjuvant treatment on perioperative morbidity and mortality, and the analysis of the tumour recurrence sites. Other secondary end-points were the correlations between disease recurrence and tumour TNM stage. Statistical analysis Based on the results of the MAGIC trial, a 5-year

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Ingo Gastinger, Frank Meyer, Thomas Lembcke, Uwe Schmidt, Henry Ptok and Hans Lippert

-87. Lindenblatt N, Park S, Alsfasser G et al.: Intraoperative fluid management in pancreatic resections - the surgeon's view. Zentralbl Chir 2008; 133: 168-75. Kehlet H: Principles of fast track surgery. Multimodal perioperative therapy programme. Der Chirurg 2009; 80: 687-89. Brandstrup B, Tonnesen H, Beier-Holgersen R et al.: Effects of intravenous fluid restriction on postoperative complications: comparison of two perioperative fluid regimens: a randomized assessor-blinded multicenter trial. Ann Surg 2003; 238: 641

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Iwona Dębińska, Katarzyna Smolińska, Jakub Osiniak and Piotr Paluszkiewicz

References Buchler MW, Wagner M, Schmied BM et al.: Changes in morbidity after pancreatic resection: toward the end of completion pancreatectomy. Arch Surg 2003; 138: 1310-14. Muller-Nordhorn J, Bruggenjurgen B, Bohmig M et al.: Direct and indirect costs in a prospective cohort of patients with pancreatic cancer. Aliment Pharmacol Ther 2005; 22: 405-15. DeOliveira ML, Winter JM, Schafer M et al.: Assessment of complications after pancreatic surgery: A novel grading system

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Jēkabs Krastiņš, Aigars Pētersons and Aivars Pētersons

REFERENCES Bagshaw, S. M., Brophy, P. D., Cruz, D., Ronco, C. (2008). Fluid balance as a biomarker: Impact of fluid overload on outcome in critically ill patients with acute kidney injury. Crit. Care , 12 (4), 169. Hassinger, A. B., Wald, E. L., Goodman, D. M. (2014). Early postoperative fluid overload precedes acute kidney injury and is associated with higher morbidity in pediatric cardiac surgery patients. Pediatr. Crit. Care Med ., 15 , 131–138. Hazle, M. A., Gajarski, R. J., Yu, S., Donohue, J., Blatt, N. B. (2013). Fluid overload in

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Arpad Ivanecz, Bojan Krebs, Andraz Stozer, Tomaz Jagric, Irena Plahuta and Stojan Potrc

the study. Those laparoscopic patients were compared to patients that underwent open simultaneous liver and colorectal resection for stage IV colorectal cancer. A propensity score matching was applied to identify the most comparable patients from the open surgery group. Primary endpoints of the study were perioperative and oncologic outcomes. Secondary endpoints of the study were overall survival (OS) and disease-free survival (DFS). Neoadjuvant and adjuvant therapy Patients with rectal advanced local disease (≥ T3 and/or ≥ N1) and SCLM received short

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Sachidanand Gautam, Ojha Piyush and Sharma Anubhav

KR, Wu SZ, Shi WM, et al. Neurosurgical outcomes in a modern series of 400 craniotomies for treatment of parenchymal tumors. Neurosurgery 1998;42:1044-55. 11.Brell M, Ibanez J, Caral L, Ferrer E. Factors influencing surgical complications of intra-axial brain tumours. Acta Neurochir (Wien) 2000;142:739-50. 12.Chang SM, Parney IF, McDermott M, Barker FG 2nd, Schmidt MH, Huang W, et al. Perioperative complications and neurological outcomes of first and second craniotomies among patients enrolled in the Glioma Outcome Project. J