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Teresa Iwaniec, Joanna Zdziarska and Artur Jurczyszyn

Multiple myeloma (MM) is a rare malignancy, characterized by clonal proliferation of plasma cells. Monoclonal immunoglobulin (paraprotein), secreted by plasmocytes, can cause plasma hyperviscosity and renal damage. Proliferation of plasma cells can lead to bone marrow suppression and cause hypercalcaemia. These features of MM give rise to different symptoms, such as bone pain from direct skeletal involvement, fatigue from anemia, or headache from hyperviscosity. The incidence of MM is estimated at 4.5‑6/100 000 [1]. It mostly (90%) affects people above 50

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Aleksander Barinow-Wojewódzki, Maria Laurentowska, Katarzyna Domaszewska, Filip Lesiński, Anna Kaliszewska-Szczepaniak and Tadeusz Rychlewski

, 723-728. Coleman E. A., Conn S., Hall-Barrow J., Richards K., Gaylor D., Stewart B, Feasibility of exercise during treatment for multiple myleoma. Cancer Nurs., 2003, 26, 410-419. Pinto B. M., Clark M. M., Maruyama N. C., Feder S. I. Psychological and fitness changes associated with exercise participation among women with breast cancer. Psycho-Oncology, 2003, 12, 118-126. Hayes S., Davies P. S. W., Pareker T., Bashford J. Total energy expenditure and body composition changes following