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M. Giretová, Ľ. Medvecký, E. Petrovová, D. Čížková, D. Mudroňová and J. Danko
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Mesenchymalstemcell (MSC) is a multipotential nonhaematopoietic progenitor cell that is able to differentiate into various cell lineages. MSC can differentiate into osteoblasts, chondrocytes, myocytes, adipose tissues, endothelial cells, neuron-like cells, cardiomyocytes and hepatocytes. MSCs lack expression of co-stimulatory molecules, are capable of escaping from alloantigen recognition and, hence, have low immunogenicity. This is why MSCs are candidate cells to prevent rejection in transplant therapy and can be a potential treatment
Güleser Saylam, Ömer Bayır, Salih Sinan Gültekin, Ferda Alparslan Pınarlı, Ünsal Han, Mehmet Hakan Korkmaz, Mehmet Eser Sancaktar, İlkan Tatar, Mustafa Fevzi Sargon and Emel Çadallı Tatar
) decreases levels of free oxygen radicals. Even though it seems to be a cytoprotective agent, amifostine has many adverse effects, limiting its widespread use. Pilocarpine is used for symptom relief, but none of the medications mentioned above have been advocated for prevention or symptomatic treatment of salivary gland damage. 5 - 10 However, to improve the patients’ quality of life and decrease the associated morbidities; new regenerative solutions are needed to obtain functional restoration and repair in affected tissues.
Mesenchymalstemcells (MSCs) isolated from