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Yu Zhao

1 Introduction The hypothesis that inflammation causes cancer cell proliferation emerged about 150 years ago [ 1 ]. The logical relationship between cancer and inflammation is not novel today. However, recent studies have expanded the concept that inflammation is involved in cancer progression {Karan, 2016 #1364}. It has been made clear that the cancer microenvironment, which is mainly populated by inflammatory cells, is an indispensable participant in the neoplastic process, metastasis, fostering of proliferation, and survival [ 2 , 3 ]. Additionally

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Theodora Benedek

References 1. Slocum C, Kramer C, Genco A. Immune dysregulation mediated by the oral microbiome: potential link to chronic inflammation and atherosclerosis. J Int Med. 2016;280:114-128. 2. Chukkapalli SS, Easwaran M, Rivera-Kweh MF, et al. Sequential Colonization of Periodontal Pathogens in Induction of Periodontal Disease and Atherosclerosis in LDLRnull Mice. Pathog Dis. 2017; pii: ftx003. 3. Lu Q, Jin L. Human gingiva is another site of C-reactive protein formation. J Clin Periodontol. 2010

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Mladen Pavlovic, Ivan Jovanovic and Nebojsa Arsenijevic

REFERENCES 1. Zuber Shaikh P. Cytokines & their physiologic and pharmacologic functions in inflammation: A review. Int J Pharm Life Sci. 2011;2(11):1247–63. 2. Dinarello C a. Historical Review of Cytokines. Eur J Immunol. 2007;37(Suppl 1):S34–45. 3. Akdis M, Aab A, Altunbulakli C, Azkur K, Costa RA, Crameri R, et al. Interleukins (from IL-1 to IL-38), interferons, transforming growth factor beta, and TNFalpha: Receptors, functions, and roles in diseases. J Allergy Clin Immunol. 2016 Aug; 4. Soufli I, Toumi R, Rafa H, Touil-Boukoffa C

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Dimirtinka Zapryanova, Teodora Mircheva, Tsanko Hristov, Lazarin Lazarov, Aleksander Atanasov, Yoana Petrova and Damyan Lalev

.info/normaldogandcatbloodvalues.htm. 3. Muthny, T., Kovarik, M., Tilser, I. & Holecek, M. (2008). Protein metabolism in slow- and fast-twitch skeletal muscle during turpentine-induced inflammation, Int. J. Exp. Path., 89, 64-71. DOI: 10.1111/j.1365-2613.2007.00553.x 4. Cerón, J.J., Eckersall, P.D. & Martínez-Subiela, S. (2005). Acute phase proteins in dogs and cats: current knowledge and future perspectives, Veterinary Clinical Pathology, 34(2), 85-99. DOI: 10.1111/j.1939-165X.2005.tb00019.x. 5. Petersen, H.H., Nielsen, J.P. & Heegaard, P.M.H. (2004). Application of

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Hamideh Kadeh, Ghazal Derakhshanfar and Shirin Saravani

’s syndrome. Clin Exp Rheumatol. 1997;16:63-5. 19. Walsh LJ. Mast cells and oral inflammation. Crit Rev Oral Biol Med. 2003;14:188-98. 20. Smith G, Smith AJ, Basu MK. Mast cells in human odontogenic cysts. J Oral Pathol Med. 1989;18:274-8.

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Xifeng Dong

Zhu J, Quyyumi AA, Norman JE, et al . Cytomegalovirus in the pathogenesis of atherosclerosis: the role of inflammation as reflected by elevated C-reactive protein levels. J Am Coll Cardiol, 1999, 34 (6):1738-1743. 8 Wang Y, Duan L, Wang Z, et al . Significance of C-reactive protein test in infectious diseases. People’s military surgeon, 2007, 50 (7):419-420. 9 Wang P. Clinical value of C-reactive protein test for infectious diseases of the lower respiratory tract. Journal of clinical and experimental medicine, 2006, 4(4):363-364. 10 Ewart H K M

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H.K. Aggarwal, Deepak Jain, Rahul Chauda, Shailesh Bhatia and Rajnish Sehgal

, Wesson DE, Wolman SL, Stewart S, Whitewell J, et al. Nutritional assessment: a comparison of clinical judgement and objective measurements. N Engl J Med 1982; 306: 969–72. 8. Kalantar-Zadeh K, Kopple JD, Block G. A malnutrition inflammation score is correlated with morbidity and mortality in maintenance hemodialysis patients. Am J Kidney Dis 2001; 38: 1251–63. 9. Tonelli M, Sacks F, Pfeffer M, Jhangri GS, Curhan G: Biomarkers of inflammation and progression of chronic kidney disease. Kidney Int 2005; 68: 237–45. 10. Kopple JD: Nutritional status as a

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Fereshteh Aliasghari, Azimeh Izadi, Masoumeh Jabbari, Bahareh Imani, Bahram Pourghassem Gargari, Foad Asjodi and Sara Ebrahimi

, Goverud I, et al. Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2. Journal of Hepatology 2006; 44(6): 1167–74. 10. Yang R-Z, Lee M-J, Hu H, Pray J, Wu H-B, Hansen BC, et al. Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action. American Journal of Physiology-Endocrinology and Metabolism 2006; 290(6): E1253–E61. 11. Heiker JT. Vaspin (serpinA12) in obesity, insulin resistance, and inflammation. Journal of Peptide Science 2014; 20

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Nora Rat, Adriana Mitre, Szilamér Korodi, István Benedek, Erzsébet Lázár, Johanna Kéri, Annamária Pakucs and István Benedek

, Zaroff JG, Olgin JE. Interleukin-6 and atrial fibrillation in patients with coronary artery disease: data from the Heart and Soul Study. Am Heart J . 2008;155:303-309. 19. Tselentakis EV, Woodford E, Chandy J, Gaudette GR, Saltman AE. Inflammation effects on the electrical properties of atrial tissue and inducibility of postoperative atrial fibrillation. J Surg Res . 2006;135:68-75. 20. Chung MK, Martin DO, Sprecher D, et al. C-reactive protein elevation in patients with atrial arrhythmias: inflammatory mechanisms and persistence of atrial fibrillation

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Piotr Chmielewski

References Aird KM, Zhang R. 2014. Metabolic alterations accompanying oncogene-induced senescence. Mol Cell Oncol 1:e963481. Alexander RW. 1994. Inflammation and coronary artery disease. N Engl J Med, 331:468–9. Arai Y, Martin-Ruiz CM, Takayama M, Abe Y, Takebayashi T, Koyasu S, Suematsu M, Hirose N, von Zglinicki T. 2015. Inflammation, but not telomere length, predicts successful ageing at extreme old age: A longitudinal study of semi-supercentenarians. EBioMedicine 2:1549–58. Bauer ME, De la Fuente M. 2013. Oxidative stress, inflammaging