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Teresa Iwaniec, Joanna Zdziarska and Artur Jurczyszyn

polymerization [ 14 , 15 , 16 , 17 ] or systemic fibrinolysis [ 18 ]. Abnormal screening coagulation test results, including prothrombin time (PT), activated partial thromboplastin time (APTT), and thrombin time (TT), are commonly encountered in patients with plasma cell neoplasms and are not typically associated with clinically significant bleeding [ 4 , 5 ]. We describe a patient who was accidentally diagnosed with multiple myeloma during diagnostic work-up of screening coagulation tests prolongation. A 71-year-old patient diagnosed with renal tumor was referred to the

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Lukas Duraj, J. Stasko, M. Hasko, M. Fedor, P. Chudy, J. Sokol, R. Limonova, I. Skornova, J. Danko and P. Kubisz

, Benchaib M, Fontaine O, Levrat A, Massignon D, Touzet S, Rudigoz R, Berland M. Coagulation assessment by rotation thrombelastometry in normal pregnancy. Thromb Haemost 2009; 101: 755 - 761. 5. Herbstreit F, Winter EM, Peters J, Hartmann M. Monitoring of haemostasis in liver transplantation: comparison of laboratory based and point of care tests. Anaesthesia 2010; 65 (1): 44-49. 6. Spalding GJ, Hartrumpf M, Sierig T, Oesberg N, Kirschke CG, Albes JM. Cost reduction of perioperative coagulation management in cardiac surgery: value of

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Jovan Antović

References Antović A. Screening haemostasis-looking for global assays: the Overall Haemostasis potential (OHP) meth-hod-a possible tool for laboratory investigation of global haemostasis in both hypo- and hypercoagulable conditions. Curr Vasc Pharmacol 2008; 6: 173-85. Lippi G, Franchini M, Targher G, Favaloro EJ. Help me, Doctor! My D-dimer is raised. Ann Med 2008; 40: 594-605. Bockenstedt P. D-dimer in venous thromboembolism. N Engl J Med 2003; 349: 1203

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Piotr Radziwon, Romuald Olszański, Jolanta Korsak and Piotr Siermontowski

sickness of rabbits. J Appl Physiol 1987;2:1772-1779. 10. Baj Z, Olszański R, Majewska E, Konarski M. The effect of air and nitrox diving on platelet activation tested by flow cytometry. Aviat Space Environ Med 2000;71:925-928. 11. Olszański R. Evaluation of heliox saturated diving on the basis of selected haemostasis parameters. Bull Inst. Marit Trop Med 1998;49:117-121. 12. Hyldegaard O, Madsen J. Effect of air, heliox and oxygen breathing on air bubbles in aqueous tissues in the rat. Undersea Hyper Med 1994

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Sagir G. Ahmed, Umma A. Ibrahim and Modu B. Kagu

center in South India. Pathog Global Health 2016; 110: 287-291. doi: 10.1080/20477724.2016.1248171. 24. Mehra B, Bhattar S, Bhalla P, Rawat D. Rapid tests versus ELISA for screening of HIV infection: our experience from a voluntary counselling and testing facility of a tertiary care centre in North India. ISRN AIDS 2014; 2014: 296840. doi: 10.1155/2014/296840. 25. Orkuma JA, Egesie JO, Banwat EB, et al. HIV screening in blood donors: rapid diagnostic test versus enhanced ELISA. Niger J Med 2014; 23: 192-200. 26. Yang JF

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Sandra Margetić

review. Br J Haematol 2006; 132: 171-96. 44. Merriman L, Greaves M. Testing for thrombophilia: an evidence-based approach. Postgrad Med J 2006; 82: 699-704. 45. Lindhoff-Last E, Luxembourg B. Evidence-based indications for thrombophilia screening. Vasa 2008; 37: 19-30. 46. Lussana F, Dentali F, Abbate R, D’Aloja E, D’Angelo A, De Stefano V, et al. Screening for thrombophilia and antithrombotic prophylaxis in pregnancy: guidelines of the Italian Society for Haemostasis and Thrombosis (SISET). Thromb Res 2009; 124: 19

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Gorana Mitić

recurrent venous thromboembolism in patients with inherited deficiency of natural anticoagulants antithrombin, protein C and protein S. Haematologica 2006; 91(5): 695-8. 13. Coppens M, Reijnders JH, Middeldorp S, Doggen CJ, Rosendaal FR. Testing for inherited thrombophilia does not reduce recurrence of venous thrombosis. J Thromb Haemost 2008; 6: 1474-7. 14. Mahmoodi BK, Brouwer JL, Ten Kate MK, Lijfering WM, Veeger NJ, Mulder AB, Kluin-Nelemans HC, van der Meer J. A prospective cohort study on the absolute risk of venous thromboembolism

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Serefden Acikgoz, Deniz Akduman, Zeynep Eskici, Murat Can, Gorkem Mungan, Berrak Guven, Füsun Comert and Vildan Sumbuloglu

References Mujun Y, Nardella A, BS, MT(ASCP), SH; Pechet L. Screening tests of disseminated intravascular coagulation: Guidelines for rapid and specific laboratory diagnosis. Crit Care Med 2000; 28: 1777-80. Lundahl TH, Lindahl TL, Fagerberg IH, Egberg N, Bunescu A, Larsson A. Activated platelets and impaired platelet function in intensive care patients analyzed by flow cytometry. Blood Coagul Fibrinolysis 1996; 7: 218-20. Levi M, Toh CH, Thachil J, Watson HG. Guidelines for the

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Giuseppe Lippi and Camilla Mattiuzzi

bleeding disorders shall be equipped with a clinical laboratory capable to perform second-line and even third-line hemostasis tests, whilst a peripheral hospital within the same network would only need a basic hemostasis laboratory, since patients with severe bleeding disorder, either congenital or acquired, would be generally admitted and managed elsewhere ( 11 ). In the case that a patient with a bleeding syndrome is brought to a peripheral facility, the local »spoke« laboratory can then support clinicians with a panel of first-line (screening) hemostasis tests (e

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Lorraine M. Flaherty, Brian P. Flaherty, Rebecca Kruse-Jarres and Barbara A. Konkle

elderly. Ann Acad Med Singapore. 2005;34(1):60-72. 22. Tromp AM, Pluijm SM, Smit JH et al. Fall-risk screening test: a prospective study on predictors for falls in community-dwelling elderly. J Clin Epidemiol. 2001;54(8):837-44. 23. Kwan MM, Close JC, Wong AK, Lord SR. Falls incidence, risk factors, and consequences in Chinese older people: a systematic review. J Am Geriatr Soc. 2011;59(3):536-43. 24. Fessel KD, Nevitt MC. Correlates of fear of falling and activity limitation among persons with rheumatoid arthritis