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Mansur Rahnama, Łukasz Czupkałło, Maryla Kozicka-Czupkałło and Michał Łobacz

References 1. Ganowicz E. Salivary Diagnostics – Diseases of the Oral Cavity. Dent Med Probl. 2011;48(3):421-30. 2. Miller CS, Foley JD, Bailey AL. et al. Current developments in salivary diagnostics. Biomark Med. 2010;4:171-89. 3. Bostanci N, İlgenli T, Emingil G, et al. Gingival crevicular fluid levels of RANKL and OPG in periodontal diseases: implications of their relative ratio. J Clin Periodontol. 2007;34:370-6. 4. Gilowski Ł, Wiench R, Płocica I, et al. Płyn dziąsłowy – czym jest i co umożliwia? Czas Stomatol. 2007;3:171-8. 5. Sharry JJ

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Liljana Bogdanovska, Mirjana Popovska, Aneta Dimitrovska and Rumenka Petkovska

inflammation: A new paradigm for the pathogenesis of periodontal diseases, J. Dent. Res . 8 (2003) 12-37; DOI: 10.1177/154405910308200202. 4. R. A. Seymour, Effects of medications on the periodontal tissues in health and disease, Periodontol. 2000 40 (2006) 120-129; DOI: 10.1111/j.1600-0757.2005.00137.x. 5. H. Aras, F. Çaglayan, G. N. Güncü, A. Berberoìlu and K. Kilinc, Effect of systematically administered naproxen sodium on clinical parametars and myeloperoxidase and elastase - like activity levels in gingival crevicular fluid, J

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Sittisak Honsawek and Wannee Unwerawattana

References 1. Preshaw PM, Seymour RA, Heasman PA. Current concepts in periodontal pathogenesis. Dent Update. 2004; 31: 574-8. 2. Kornman KS, Page RC, Tonetti MS. The host response to the microbial challenge in periodontitis: assembling the players. Periodontol. 2000. 1997; 14:33-53. 3. Kennett CN, Cox SW, Eley BM. Investigations into the cellular contribution to host tissue proteases and inhibitors in gingival crevicular fluid. J Clin Periodontol. 1997; 24:424-31. 4. Okada H, Murakami S. Cytokine

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Berrak Guven and Cigdem Turer

References 1. Christenson RH. Biochemical markers of bone metabolism: An overview. Clin Biochem, 1997;30:573-593. 2. Civitelli R, Armamento-Villareal R, Napoli N. Bone turnover markers: understanding their value in clinical trials and clinical practice. Osteoporos Int, 2009;20:843-851. 3. Nakashima K, Roehrich N, Cimasoni G. Osteocalcin, prostaglandin E2 and alkaline phosphatase in gingival crevicular fluid: their relations to periodontal status. J Clin Periodontol, 1994;21:327-333. 4. Lowther

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Marwa Abdelhakim Gomaa, Hoda Mohamed El Guindy and Enas Arafa El-Zamrany

;291:223-234. 7. Ingman T, Tervahartiala T, Ding Y, Tschesche H, Haerian A, Kinane DF et al. Matrix metalloproteinases and their inhibitors in gingival crevicular fluid and saliva of periodontitis patients. J Clin Periodontol, 1996;23:1127-1132. 8. Sorsa T, Ingman T, Suomalainen K, Halinen S, Saari H, Konttinen YT et al. Cellular source and tetracycline inhibition of gingival crevicular fluid collagenase of patients with labile diabetes mellitus. J Clin Periodontol, 1992;19:146-149. 9. Correa FO, Gonçalves D, Figueredo CM, Gustafsson A, Orrico SR

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Lora S. Ribagin and Maya R. Rashkova

, Siloşi I, Oprea B, Pirici D. Correlations between the gingival crevicular fluid MMP8 levels and gingival overgrowth in patients with fixed orthodontic devices. Rom J Morphol Embryol 2010;51(3):515-9. 5. Giannopoulou C, Mombelli A, Tsinidou K, Vasdekis V, Kamma J. Detection of gingival crevicular fluid cytokines in children and adolescents with and without fixed orthodontic appliances. Acta Odontol Scand 2008;66(3):169-73. 6. Grieve WG, Johnson GK, Moore RN, Reinhardt RA, DuBois LM. Prostaglandin E (PGE) and interleukin- 1b levels in

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Hulya Sariaslan Goleli, Murat Akkaya and Melike Camgoz

, Deinzer R. Effects of plaque, psychological stress, and gender on crevicular Il-1 and Il-1ra secretion. J Clin Periodontol, 2003;30:238-248. 23. Alexander MB, Damoulis PD. The role of cytokines in the pathogenesis of periodontal disease. Curr Opin Periodontol, 1994;39-53. 24. Ebersole JL, Cappelli D, Steffen MJ. Characteristics and utilization of antibody measurements in clinical studies of periodontal disease. J Periodontol, 1992;63:1110-1116. 25. Lamster IB. The host response in gingival crevicular fluid: potential applications in periodontitis

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Lukasz Czupkallo, Mansur Rahnama, Dominik Kielbowicz, Michal Lobacz and Maryla Kozicka-Czupkallo

pathological bone resorption. Crit. Rev. Oral Biol. Med ., 15, 64-81, 2004. 12. Liu D. et al.: Expression of RANKL and OPG mRNA in periodontal disease: possible involvement in bone destruction. Int. J. Mol. Med ., 11, 17-21, 2003. 13. Manolagas S.C.: Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocr. Rev ., 21, 115-137, 2000. 14. Mogi M. et al.: Differential expression of RANKL and osteoprotegerin in gingival crevicular fluid of patients with periodontitis. J. Dent. Res

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Ilma Robo and Ruzhdie Qafmolla

References 1. Bastos MF, Lima JA, Vieira PM, et al . TNF-α and IL-4 levels in generalized aggressive periodontitis subjects. Oral Dis , 2009; 15(1):82-87. 2. Delima AJ, Van Dyke TE . Origin and function of the cellular components in gingival crevice fluid. Periodontol 2000 , 2003; 31(1):55-76. 3. Erdemir EO, Baran I, Nalcaci R, Apan T . IL-6 and IL-8 levels in GCF of the teeth supporting fixed partial denture. Oral Dis , 2010; 16(1):83-88. 4. Isik F, Sayinsu K, Arun T, Ünlüçerçi Y . Bone marker levels in gingival crevicular fluid

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Lia Maria Yero Ieremie, Luminița Lazăr and Adriana Ciurba

References 1. Wang Y., Yang PS, Oi XM, Ren JM, Ge SH.: Change of circulating TNFalpha in patients with advanced periodontitis before and after periodontal initial therapy, Shanghai Kou Qiang Yi Xue, 2003 apr; 12(2):85-87. 2. Rai B. Salivary Levels of Tumor Necrosis Factor-Alpha in 201Periodontitis, Advances in Medical and Dental Sciences, 2008;2(2):40-41. 3. Dağ A, Firat ET, Kadiroğlu AK, Kale E, Yilmaz ME. Significance of elevated gingival crevicular fluid tumor necrosis factor-alpha and interleukin-8 levels in