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Serdar Olt, Orhan Öznas, Haydar Bağış and Eda Tahir Turanlı

al. Chemokine (CC-motif) receptor-like 2 mRNA is expressed in hepatic stellate cells and is positively associated with characteristics of non-alcoholic steatohepatitis in mice and men. Exp Mol Pathol 2017;103(1):1-8. 5. Ozcan E, Saygun NI, Ilikci R, et al. Evaluation of chemerin and its receptors, ChemR23 and CCRL2, in gingival tissues with healthy and periodontitis. Odontology 2017;21(4):1113-21. 6. Wan M, Godson C, Guiry PJ, et al. Leukotriene B4/antimicrobial peptide LL-37 proinflammatory circuits are mediated by BLT1 and FPR2/ALX and are

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Manal M. Alkady, Phebe L. Abdel-Messeih and Neveen M. Nosseir

recurrence. Nature Reviews. Endocrinology 2014; 10: 455-65. 9. Rourke JL, Dranse HJ, Sinal CJ. Towards an integrative approach to understanding the role of chemerin in human health and disease. Obes Rev 2013; 14: 245-62. 10. Bozaoglu K, Bolton K, McMillan J, Zimmet P, Jowett J, Collier G, Walder K, Segal D. Chemerin is a novel adipokine associated with obesity and metabolic syndrome. Endocrinology 2007; 148: 4687-94. 11. Ouchi N, Parker JL, Lugus JJ, Walsh K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol

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Bogna Grygiel-Górniak, Teresa Grzelak, Krystyna Czyźewska and Mariusz Puszczewicz

, synovial fluid and serum. Ann Rheum Dis 2007; 66: 458–63. 9. Bokarewa M, Nagaev I, Dahlberg L, Smith U, Tarkowski A. Resistin, an adipokine with potent proinflammatory properties. J Immunol 2005; 174: 5789–95. 10. Gonzalez-Gay MA Gonzalez-Gay MA, Garcia-Unzueta MT, Gonzalez-Juanatey C, Miranda-Filloy JA, Vazquez-Rodriguez TR, De Matias JM, Martin J, Dessein PH, Llorca J. Anti-TNF-alpha therapy modulates resistin in patients with rheumatoid arthritis. Clin Exp Rheumtol 2008; 26: 311–6. 11. Roman AA, Parlee SD, Sinal CJ. Chemerin: a potential endocrine

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Pēteris Tretjakovs, Juris Hofmanis, Dace Hofmane, Gita Krieviņa, Leons Blumfelds, Vitolds Mackēvičs, Aivars Lejnieks and Guntis Bahs

inhibitor of metalloproteinase-2 is related to cardiac fibrosis and dysfunction in the chronic pressure-overloaded human heart. Circulation , 112 (8), 1136–1144. Ji, Q., Lin, Y., Liang, Z., Yu, K., Liu, Y., Fang, Z., Liu, L., Shi, Y., Zeng, Q., Chang, C., Chai, M., Zhou, Y. (2014). Chemerin is a novel biomarker of acute coronary syndrome but not of stable angina pectoris. Cardiovasc. Diabetol ., 13 , 145. Kammerer, A., Staab, H., Herberg, M., Kerner, C., Klöting, N., Aust, G. (2018). Increased circulating chemerin in patients with advanced carotid

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E Becer and A Çırakoğlu

of 30 amino acids. The PPARγ1 gene is expressed in nearly all cells, while PPARγ2 expression is limited mainly to adipose tissue [ 2 ]. Both PPARγ1 and PPARγ2 isoforms are an important adipogenic regulator and essential for the control of insulin sensitivity. However, PPARγ2 regulates response to nutrient intake and obesity. These characteristic properties make it a key molecule to be involved in the expression of adipokines such as leptin, adiponectin, resistin and chemerin, which may act as modulators of energy metabolism and insulin action [ 3 ]. Moreover

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Ioan Tilea, Dorina Petra, Elena Ardeleanu, Adina Hutanu and Andreea Varga

dipping pattern of nocturnal blood pressure in patients with cardiovascular risk factors. PLoS One. 2014;9(8): e105977. 82. Meric M, Soylu K, Avci B, et al – Evaluation of plasma chemerin levels in patients with non-dipper blood pressure patterns. Med Sci Monit. 2014;20:698–705. 83. Zheng H, Xie X, Xie N, Xu H, et al – Sphingomyelin levels in nondipper and dipper hypertensive patients. Exp Ther Med. 2014;7:599-603. 84. Cayli M, Gur M, Elbasan Z, et al – High-Sensitivity Cardiac Troponin T Predicts Nondipper Hypertension in Newly Diagnosed Hypertensive

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Fereshteh Aliasghari, Azimeh Izadi, Masoumeh Jabbari, Bahareh Imani, Bahram Pourghassem Gargari, Foad Asjodi and Sara Ebrahimi

. Esteghamati A, Noshad S, Mousavizadeh M, Zandieh A, Nakhjavani M. Association of vaspin with metabolic syndrome: the pivotal role of insulin resistance. Diabetes & Metabolism Journal 2014; 38(2): 143–9. 24. Alkady MM, Abdel-Messeih PL, Nosseir NM. Assessment of serum levels of the adipocytokine chemerin in colorectal cancer patients. J Med Biochem 2018; 37: 313–9. 25. Kukla M, Zwirska Korczala K, Gabriel A, Waluga M, Warakomska I, Szczygiel B, et al. Chemerin, vaspin and insulin resistance in chronic hepatitis C. Journal of Viral Hepatitis 2010; 17(9): 661

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Primož Kotnik, Pamela Fischer Posovszky and Martin Wabitsch

differentiation. Int J Obes Relat Metab Disord 2001; 25: 8-15. 105. Goralski KB, McCarthy TC, Hanniman EA, Zabel BA, Butcher EC, Parlee SD. et al. Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism. J Biol Chem 2007; 282: 28175-88. 106. Shin HY, Lee DC, Chu SH, Jeon JY, Lee MK, Im JA. et al. Chemerin levels are positively correlated with abdominal visceral fat accumulation. Clin Endocrinol (Oxf.) 2012; 77: 47-50. 107. Reyman M, Verrijn Stuart AA, van Summeren M, Rakhshandehroo M, Nuboer R, de Boer FK

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Mariana Cornelia Tilinca, Eniko Csilla Barabas-Hajdu, Gizella Tusa Ferencz and Eniko Nemes-Nagy

treatment increases complete Fatty Acid oxidation, mitochondrial oxidative capacity, and biogenesis in muscle of insulin-resistant mice. Diabetes 2012;61:310–320. DOI: 10.2337/db11-0100 28. Dray C, Knauf C, Daviaud D, Waget A, Boucher J, Buleon M, et al. Apelin stimulates glucose utilization in normal and obese insulinresistant mice. Cell Metab. 2008; 8:437–445. DOI: 10.1016/j.cmet.2008.10.003 29. Guvenc Y, Var A, Goker A, Kuscu NK. Assessment of serum chemerin, vaspin and omentin-1 levels in patients with polycystic ovary syndrome. J Int Med Res. 2016 Aug; 44

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Alina Bodea and Amorin Remus Popa

test vary according to the level of insulin resistance in pregnant women. J Clin Endocrinol Metab 99: 1862-1869, 2014. 21. Jialal I, Devaraj S, Kaur H, Adams-Huet B, Bremer AA. Increased chemerin and decreased omentin-1 in both adipose tissue and plasma in nascent metabolic syndrome. J Clin Endocrinol Metab 98: E514-E517, 2013. 22. Lin SX, Berlin I, Younge R et al. Does elevated plasma triglyceride level independently predict impaired fasting glucose? The multi-ethnic study of atherosclerosis (MESA). Diabetes Care 36: 342-347, 2013