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Sudden Cardiac Death and Idiopathic Ventricular Arrhythmias

Abstract

Ventricular arrhythmias (VAs) in patients without structural heart disease can be found in a significant portion of the general population. The prognosis of patients with idiopathic VA is usually favorable and patients are often asymptomatic. However, sudden cardiac death (SCD) as a consequence of idiopathic VA has been reported. The aim of this review is to present an overview of the association between idiopathic VA and SCD.

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Modern Technology for Prevention of Sudden Cardiac Death – a Clinical Update on Device Therapy in Children with Congenital Heart Diseases

Abstract

Sudden cardiac death in children is one of the most devastating conditions that can be encountered in acute cardiac care. Intracardiac device therapy, providing prompt and effective treatment in malignant ventricular arrhythmia or in severe conduction abnormalities, is a promising tool to reduce the incidence of this fatal condition. However, the implementation of device-based therapy in the pediatric population is currently limited by the lack of clinical studies on large number of subjects. As a result, indications for device therapy in pediatric patients are still unclear in many circumstances. There are also several particularities related to device implantation in pediatric age, such as the somatic growth leading to a mismatch between chamber size and lead length, or the difficulties of implantation technique in children with small body weight. This study aims to present an update on the current advantages and limitations of device-based therapy for treating severe malignant arrhythmia or conduction disorders in children at risk for sudden cardiac death.

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Case Report of the Patient with Acute Myocardial Infarction: “From Flatline to Stent Implantation”

References 1. Zipes DP, Camm AJ, Borggrefe M, et al. ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death – executive summary: Eur Heart J 2006;27:2099–140. https://doi.org/10.1016/j.jacc.2006.07.008 2. Loyd JD, Adams RJ, Brown TM, et al. Heart disease and stroke statistics – 2010 update: a report from the American Heart Association. Circulation 2010; 121:e46-215. https://doi.org/10.1161/CIRCULATIONAHA.109.192667 3. Gillum RF. Gographic variation in sudden coronary death

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Sudden Cardiac Death and Post Cardiac Arrest Syndrome. An Overview

References 1. Centers for Disease Control and Prevention (CDC). Statespecific mortality from sudden cardiac death - United States, 1999, MMWR Morb Mortal Wkly Rep, 2002;51:123-6. 2. Myerburg RJ, Castellanos A. Cardiac arrest and sudden cardiac death. Braunwald E, ed. Heart Disease: A Textbook of Cardiovascular Medicine. 5th ed. Philadelphia, Pa: WB Saunders; 1997:742-779. 3. de Vreede-Swagemakers JJ, Gorgels AP, Dubois-Arbouw WI, et al. Out-of-hospital cardiac arrest in the 1990’s: a populationbased study in the

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Late arrhythmia in patients with repaired tetralogy of Fallot: who is at risk?

. Arrhythmia burden in adults with surgically repaired tetralogy of Fallot: a multi-institutional study. Circulation 2010;122:868–75. [10] Gatzoulis MA, Balaji S, Webber S, Siu S, Hokanson J, Poile C, et al. Risk factors for arrhythmia and sudden cardiac death late after repair of tetralogy of Fallot: a multicentre study. Lancet 2000;356:975–81. [11] Harrison DA, Harris L, Siu SC, MacLoghlin CJ, Connelly MS, Webb GD, et al. Sustained ventricular tachycardia in adult patients late after repair of tetralogy of Fallot. J Am Coll Cardiol 1997

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The Early Repolarization ECG Pattern – An Update

Abstract

Early repolarization pattern (ERP), a form of J-wave syndromes, was considered long time a benign ECG phenomenon. However, recent data confirmed that certain phenotypes of ERP are related to an increased risk of sudden cardiac death (idiopathic ventricular fibrillation). Our paper gives a short and practical update regarding the main issues related to ERP: epidemiological data, molecular and electrophysiological background, clinical significance and risk stratification. At the end, the future directions of research and clinical management related to ERP are presented.

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Focal Myocarditis in Professonal Female Athlete: A Case Report

ABBREVIATIONS ARVC - Arrhythmogenic right ventricular cardiomyopathy ECG – Electrocardiogram LGE - Late gadolinium enhancement LV – Left ventricle MRI - Magnetic resonance imaging MSCT - Multislice computed tomography nsVT - Non-sustained ventricular tachycardia PVC - Premature ventricular complexes RV – Right ventricle SCD – Sudden cardiac death SPECT - Single positron emission computed tomography REFERENCES 1. Corrado D, Basso C, Rizzoli G, Schiavon M, Thiene G. (2003). Does sports activity enhance the

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Application of Wavelet Based Denoising for T-Wave Alternans Analysis in High Resolution ECG Maps

References Chugh, S. S., Jui, J., Gunson, K. et al. (2004). Current burden of sudden cardiac death: Multiple source surveillance versus retrospective death certificate-based review in a large U. S. community. Journal of the American College Cardiology , 44 (6), 1268-75. Huikuri, H. V., Castellanos, A., Myerburg, R. J. (2001). Sudden death due to cardiac arrhythmias. New England Journal of Medicine , 345 (20), 1473-82. Myerburg, R. J., Kessler, K. M., Castellanos, A. (1992). Sudden

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Changes In QTc Interval Duration Among Heroin Addicts On Methadone Treatment

Abstract

This paper aimed to collect and unite facts known about the effect of methadone treatment on QTc interval prolongation that could determine precipitating factors in the development of heart arrhythmias and their consequences (Torsade de Pointes and sudden cardiac death), and to raise the methadone treatment safety level.

Studies conducted up to now clearly demonstrate that methadone therapy evokes changes in the heart’s electrical conduction, but those studies also show that QTc interval prolongation could be precipitated by other factors. The most often present risk factors in our research were dose of methadone, co-medication, and co-morbidity, but other relevant risk factors were gender, age, misuse of illicit drugs, therapy length and tobacco use.

Active participation in modern treatment processes and implementation of knowledge acquired recently into daily practice, such as setting up reutilized questionnaires and diagnostic methods to expose higher risk for complications and providing broader therapeutic range for cases of drug replacement necessity, will enhance therapy safety level and bring us to the next step of resocialization of these patients, which needs to remain the final goal of treatment.

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Applied Imagistics of Ischaemic Heart a Survey. From the Epidemiology of Stable Angina In Order to Better Prevent Sudden Cardiac Death

Graphics . Chugh SS, Kelly KL, Titus JL. Sudden cardiac death with apparently normal heart. Circulation. 2000 Aug 8;102(6):649-54. D. Dey, V.Y. Cheng, P.J. Slomka, R. Nakazato, A. Ramesh, S. Gurudevan, G. Germano, D.S.: Automated 3-dimensional quantification of noncalcified and calcified coronary plaque from coronary CT angiography, Journal of cardiovascular computed tomography 3 (6), 372-382 Flohr T.G., Leng S., Yu L., Aiimendinger T., Bruder H., Petersilka M., Eusemann C.D., Stierstorfer K., Schmidt B., McCollough C

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