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References 1. Scalvenzi, M, Lembo, S, Francia, M.G., & Balato, A. (2008). Dermoscopic patterns of superficial basal cell carcinoma. International Journal of Dermatology, 47 (10), 1015–8. 2. Moncrieff, M., Cotton, S., Claridge, E., & Hall, P. (2002). Spectrophotometric intracutaneous analysis: a new technique for imaging pigmented skin lesions. British Journal of Dermatology, 146 , 448–457. 3. http://www.melafind.com/ 4. http://www.dino-lite.com/ 5. Diebele, I., Kuzmina, I., Derjabo, A., Kapostinsh, J., Bekina, A., & Spigulis, J. (2012). Analysis of skin

References Brunicardi FC et all. Schwartz's Principles of Surgery, Eight edition, McGraw-Hill Companies, Inc; p. 432-433;1852-1826, 2005. Chrysopoulo Minas T. Flaps, Classification, article available from www.emedicine.medscape.com Converse JM. Reconstructive plastic surgery. 1977;2:3749-3763. Converse JM, Mc Carthy JG. Transplantation of skin grafts and flaps. Fisher J, Gingrass M. Basic principles of skin flaps. In: Georgiade GS, ed. Georgiade Plastic, Maxillofacial and Reconstructive Surgery. Waverly Co; 20- 22, 1992. Krizek TJ. Grafts and flaps. In: Ruberg

. Res. 2001;42:1759-1770. [5] Bouwstra JA, Gooris GS, van der Spek JA, Bras W. Structural investigations of human stratum corneum by small-angle X-ray scattering. J. Invest. Dermatol. 1991;97:1005-1012. [6] Bouwstra JA, Ponec M. The skin barrier in healthy and diseased state. Biochim. Biophys. Acta. 2006;1758:2080-2095. [7] Breathnach AS. Aspects of epidermal ultrastructure. J. Invest. Dermatol. 1975;65:2-15. [8] Breiden B, Sandhoff K. The role of sphingolipid metabolism in cutaneous permeabilitybarrier formation. Biochim Biophys Acta. 2014;1841:441-452. [9] Candi E

, 28(4), 314–328. Draelos, Z. D. (2015). A split-face evaluation of a novel pigment-lightening agent compared with no treatment and hydroquinone. Journal of the American Academy of Dermatology , 72(1), 105-107. Fan, L., Wang, H., Zhang, K., Cai, Z., He, Ch., Sheng, X., & Mo, X. (2012). Vitamin C-reinforcing silk fibroin nanofibrous matrices for skin care application. RSC Advances , 2, 4110-4119. Farage, M. A., Miller, K. W., Elsner, P., Maibach, H. I. (2013). Characteristics of the Aging Skin. Advances in Wound Care , 291, 5-10. Fracassetti, D., Costa, C., Moulay

recent medical laser developments, Las. Med. Sci ., (1), 47-66. 6. Anderson, R., & Parrish, J. (1981). The optics of human skin. J. Invest. Derm ., 77 , 13-18. 7. Wagnieres, G., Star, W., & Wilson, B. (1998). In vivo fluorescence spectroscopy and imaging for oncological applications. Photochem. Photobiol ., 68 (5), 603-632. 9825692 8. Stratonnikov, A.A., Polikarpov, V.S., & Loschenov, V.B. (2001). Photobleaching of endogenous fluorochroms in tissues in vivo during laser irradiation. Proc. SPIE , 4241 , 13-24. 9. Lihachev, A. (2011). Kinetics of laser excited

References [1] Kalia Y.N. and Guy R.H. (2001): Modeling transdermal drug release . – Adv. Drug Delivery Rev., vol.48, pp.159-172. [2] Carreras N., Alonso C., Marti M. and Lis M.J. (2015): Mass transport model through the skin by microencapsulation system . – J. Microencapsulation, vol.32, No.4, pp.358-363. [3] Cal K. (2009): Across skin barrier; known methods, new performances . – In: Frontiers in Drug Design and Discovery, vol.4 (Caldwell G.W., ur-Rahman A., Yan Z., Choudhary M.J., Eds), pp.162-188. [4] Cal K. and Stefanowska J. (2010): Methods for skin

References [1] World Health Organization (WHO): Skin cancers; available at: http://www.who.int/uv/faq/skincancer/en/index1.html , accessed 1st April 2014 [2] Lomas, A., Leonardi-Bee, J., Bath-Hextall, F. (2012). A systematic review of worldwide incidence of nonmelanoma skin cancer. Br J Dermatol. 166 (5), 1069-80. [3] Lipozenčić, J., Celić, D., Strnad, M., Jurakić Tončić, R., Pašić, A., Radoš, J., Znaor, A. (2010). Skin cancers in Croatia 2003-2005: epidemiological study. Collegium antropologicum. 34 (3); 865-869. [4] Australian Institute of Health and Welfare

References Atrux-Tallau N, Romagny C, Padios K, Denis A, Haftek M, Falson F, Pirot F, Maibach HI (2010) Arch. Dermatol. Res. 302: 435-441. Boeniger MF (2003) Ann. Occup. Hyg. 47: 591-593. Davies DJ, Ward RJ, Heylings JR (2004) Toxicol. In Vitro, 18: 351-358. De Paepe K, Roseeuw D, Rogiers V (2002) J. Eur. Acad. Dermatol. Venerol. 16: 587-594. EC (2008) EU B.45 Skin absorption-In vitro method, In OJ L 14. EU-OSHA (2008) Occupational skin diseases and dermal exposure in the European Union, European Agency for Safety and Health at Work. Luxembourg: pp. 244. Fentem

References 1. Kollias N. The interaction of light with the skin. In: Wilhelm K, Elsner P, Berardesca E, Maibach H, editors, Bioengineering of the skin: skin imaging and analysis. 2nd ed. New York: Informa Healthcare; 2007. p. 222-8. 2. Anderson R, Parrish JA. The optics of human skin. J Invest Dermatol 1981;77:13-9 3. Igarashi T, Nishino K, Nayar SK. The appearance of human skin. Technical Report: CUCS-024-05 [cited 21.01.2011.] Available at http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.87.5961&rep=rep1&type=pdf 4. Jacques S, Glickman R, Schwartz J

References 1. E. David McIntosh. (2009) - Glycylcyclines: Current Research Directions - STEP Progress in Infection (section 5). Athens , Greece: Wyeth 2. Ellis-Grosse EJ, Babinchak T, Dartois N, Rose G, Loh E.( 2005). for the Tigecycline 300 and 305 cSSSI Study Groups - The efficacy and safety of tigecycline in the treatment of skin and skinstructure infections: results of 2 double-blind phase 3 comparison studies with vancomycinaztreonam - Clinical Infectious Diseases ; 41 Suppl 5 (S341-S353). Oxford University Press. 3. Zhanel GG, Karlowsky JA, Rubinstein E