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Preoperative Evaluation of Sexual Function in Patients Undergoing Bilateral Nerve-Sparing Radical Retropubic Prostatectomy

, Gallina A, Suardi N, Capitanio U, et al. Choosing the best candidates for penile rehabilitation after bilateral nerve-sparing radical prostatectomy. J Sex Med. 2012;9(2):608-17. 16. Briganti A, Gallina A, SuardiN, Capitanio U, Tutolo M, Bianchi M, et al. Predicting erectile function recovery after bilateral nerve sparing radical prostatectomy: a proposal of a novel preoperative risk stratification. J Sex Med. 2010;7(7):2521-31. 17. Briganti A, Capitanio U, Chun FK, Karakiewicz PI, Salonia A, Bianchi M, et al. Prediction of sexual function after radical

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Quality of Sexual Life after Microsurgical Penile Denervation in Men with Primary Premature Ejaculation

References 1. Senol MG, Sen B, Karademir K, Sen H, Saraçoğlu M. The effect of male circumcision on pudendal evoked potentials and sexual satisfaction. Acta Neurol Belg. 2008;108(3):90-3. 2. Rosen RC. Sexual function assessment in the male: physiological and self-report measures. Int J Impot Res. 1998;10(2):59-63. 3. Alyaev YG, Akhvlediani ND. [Comparing efficacy of selective penile denervation and circumcision for primary premature ejaculation]. Urologiia. 2016;(1 (supp)):60-4. Russian. 4. Dimitrov P, Panchev P, Simeonov P, Vasilev V

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Sexuality of Disabled Athletes Depending on the Form of Locomotion

References Alexander MS, Brackett NL, Bodner D, Elliott S, Jackson A, Sonksen J. National Institute on Disability and Rehabilitation Research. Measurement of sexual functioning after spinal cord injury: preferred instruments. J Spinal Cord Med, 2009; 32: 226-236 Cappelleri JC, Rosen RC, Smith MD, Mishra A, Osterloh IH. Diagnostic evaluation of the erectile function domain of the International Index of Erectile Function. Urology , 1999; 54: 346–351 Consortium for Spinal Cord Medicine. Sexuality and Reproductive Health in Adults with Spinal

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Late-onset hypogonadism: Review of the problem

of screening questionnaires. Arg. Bras. Endokrinol. Metabol. , 52 (9), 1439-1447. Davidson, J. M., Chen, J. J., Crapo, L., Gray, G. D., Greenleaf, W. J., Catania, J. A. (1983). Hormonal changes and sexual function in aging men. J. Clin. Endocrinol. Metab. , 57 (1), 71-77. Ellegala, D. B., Alden, T. D., Couture, D. E., Vance, M. L., Maartens, N. F., Laws, E. R. Jr. (2003). Anemia, testosterone and pituitary adenoma in men. J. Neurosug. , 98 (5), 974-977. Feldman, H. A., Longcope, C

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An overlooked issue: sexual dysfunctions in men addicted to alcohol

its effect on quality of life in alcohol dependent men: Preliminary findings. Alcohol Alcohol 2007; 42:340-346. 5. Paparriropoulos T, Zabelis T, Tzavellas E, Karaiskos D, Zaloni R, Stachtea1 X, et al. Sexual dysfunction and alcohol abuse. Eur Neuropsychopharmacol 2009; 19:6-7. 6. Dissiz M, Oskay ÜY. Evaluation of sexual functions in Turkish alcohol-dependent males. J Sex Med 2011; 8:3181-3187. 7. Vijayasenan ME. Alcohol and sex. N Z Med J. 1981; 93:18-20. 8. Grover S, Mattoo SK, Pendharkar S, Kandappan V. Sexual Dysfunction in Patients with

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The Sexual Satisfaction Questionnaire – psychometric properties

. Wrocław: ElsevierUrban & Partner. Baumeister, R., Campbell, J., Krueger, J., Vohs, K. (2003). Does high self- esteem cause better performance, interpersonal success, happiness, or healthier lifestyles? Psychological science in the public interest. 4,1, s.1-44. Dolińska- Zygmunt, G. (2001). Podstawy psychologii zdrowia. Wrocław: Wydawnictwo Uniwersytetu Wrocławskiego. Dundon, C., Rellini, A. (2010) More than sexual function: predictors of sexual satisfaction In a sample of woman age 40-70. Journal of Sex Medicine, 2010, 7

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The role of oxytocin in the pathogenesis and treatment of schizophrenia


Introduction: Until recently, oxytocin was mainly associated with the pathophysiology of childbirth and sexual functions, but lately this hormone has become the object of interest to psychiatry and psychology due to the significant influence of oxytocin on human behavior in the field of social and emotional functioning. Current scientific research focuses on the participation of oxytocin in the pathogenesis and therapy of mental disorders.

Aim: The aim of the paper is to present, on the basis of available literature, the significance of oxytocin for various psychological functions, with particular emphasis on the influence of oxytocin on the course and clinical picture of schizophrenia.

Method: Available articles from the Medline / PubMed database were analyzed, which were searched using keywords: oxytocin, schizophrenia, therapeutic use of oxytocin, social cognition, positive symptoms, negative symptoms and time descriptors: 2013-2017. There are included articles published in Polish and English.

Results:The research results carried out so far suggest that oxytocin plays a significant role in modulating complex socio-emotional behaviors in schizophrenic patients. The existing research results also indicate a relationship between the dysregulation of the oxytocinergic system and the pathophysiology of schizophrenia. Many of the studies prove that there is a relationship between the level of oxytocin in the patients' blood plasma and the severity of the disease symptoms. Recent genetic studies indicate a possible relationship between polymorphism of oxytocin genesand polymorphism of oxytocin receptor genes and the risk of developing schizophrenia.

Conclusions: Contemporary research on the therapeutic potential of oxytocin and its influence on the functioning of schizophrenia patients seem to be very promising and may contribute to increasing the effectiveness of treatment of schizophrenia and possibly other mental disorders, which in turn will improve the quality of life of patients in cognitive, social and emotional functioning.

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Current aspects of polycystic ovary syndrome I: definition, pathophysiology, clinical manifestations, diagnosis and complications


Polycystic ovary syndrome (PCOS) is the most frequent endocrine disease among women with childbearing potential, the best-known cause of hirsutism, with a hypothesized prevalence of 8-22%. The first part of the paper discusses the conceptional evolution of the syndrome, from its description in 1935 by Stein and Leventhal till today. It describes the changes in the criteria systems, emphasizing that the Rotterdam criteria, proposed in 2003 by the European Society for Human Reproduction and Embryology/American Society for Reproductive Medicine, are still valid today. This system basically differs from earlier (1990) NIH-criteria in one aspect: it introduced two newer phenotypes, one without hyperandrogenism and the other with ovulatory cycles, so it distinguishes 4 phenotypes. The etiology and pathogenesis of PCOS is heterogeneous, multifactorial, poorly understood. We present the 3 leading hypotheses (1 - hypothalamo-hypophyseal disturbances, 2 – primary enzyme disorders in ovarian, or ovarian/adrenal steroidogenesis, resulting primarily in hyperactivity of 17alpha-hydroxylase/17,20-lyase, 3 – insulin resistance-hyperinsulinism and other metabolic dysfunctions). We emphasize the role of genetically determined hyperandrogenism, that of insulin resistance-hyperinsulinism and the importance of reinforcing each other. Subsequently, the aggravating aspects of the frequently associated metabolic syndrome are discussed, and then the effects of the mentioned pathological processes on the endocrine and other organ structures participating in the regulation of sexual functions. We stress the hypothetical role of perinatal and pubertal androgen exposition in the pathogenesis of PCOS. The mechanisms of anovulation and those of the endometrial lesions are discussed, too. The clinical manifestations, the paraclinical and laboratory examinations, the positive and differential diagnosis and the complications are also presented. We intend to deal with the therapeutic aspects of PCOS in an upcoming paper.

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Quality of life and sexual activity of women suffering from Polycystic Ovary Syndrome (PCOS)

in polycystic ovary syndrome: a hidden facet in South Asian women. BJOG. 2011; 118(3): 319-328. 11. Janssen OE, Hahn S, Tan S et al. Mood and sexual function in polycystic ovary syndrome. Semin Reprod Med. 2008; 26(1): 45-52. 12. WHOQOL-BREF. Introduction, administration, scoring and generic version of the assessment. Field Trial Version. WHO, Genewa 1996. 13. The Female Sexual Function Questionnaire (SFQ-28). Background and Scoring. Pifzer Ltd, Sandwich 1997, France. 14. Coffey S, Mason H. The effect

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Quality of life in patients with cervical cancer FIGO IIb stage after concomitant chemoradiotherapy

. Longitudinal study of sexual function and vaginal chenges after radiotherapy for cervical cancer. Int J Radiat Oncol Biol Phys 2003; 56: 937-49. Velenik V, Oblak I, Anderluh F. Quality of life in patients after combined modality treatment of rectal cancer: Report of a prospective phase II study. Radiol Oncol 2008: 42: 207-14. Greimel ER, Kuljanic Vlasic K, Waldenstrom AC, Duric VM, Jensen PT, Singer S, et al. The European Organisation for Research and Tretmant of Cancer (EORTC). Quality of life qustionnaire cervical

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