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An overlooked issue: sexual dysfunctions in men addicted to alcohol

References 1. Zgliczyński SW. Alkohol w Polsce. Infos 2016; 215. 2. Nutt DJ, King AL, Phillips LD. Drug harms in the UK: a multicriteria decision analysis. Lancet 2010; 376: 1558–1565. 3. Wylie KR, Steward D, Seivewright N, Smith D. Prevalence of sexual dysfunction in three psychiatric outpatient settings: A drug misuse service, an alcohol misuse service and a general adult psychiatry clinic. Sex Relat Ther, 2002; 17:149-60. 4. Grinshpoon A, Margolis A, Weizman A, Ponizovsky AM. Sildenafil citrate in the treatment of sexual dysfunction and

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Review of a New Multimodal Antidepressant Vortioxetine

Abstract

Vortioxetine is a novel antidepressant with two mechanisms of action – direct effect on several serotonin receptors and serotonin re-uptake inhibition. It shows antidepressant, anxiolytic and cognitive effects during the treatment of major depressive disorder (MDD). The aim of this article was to summarize the use of vortioxetine in clinical studies and assess the efficacy and tolerability. Most of the studies reported a statistically significant efficacy for vortioxetine versus placebo. In addition, vortioxetine showed efficacy in patients with an inadequate response to selective serotonin re-uptake inhibitors (SSRI) or serotonin-noradrenaline re-uptake inhibitors (SNRI) monotherapy and improved cognitive function in patients with MDD. In these studies, vortioxetine was well tolerated – most common observed adverse effect was nausea – and it was not associated with clinically important changes in laboratory test results or vital signs. Vortioxetine showed a relatively low incidence of sexual dysfunction.

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Brief communication (Original). Effect of sacral nerve electrostimulation on sex dysfunction in male rats with spinal cord injury

AJK, Cava A, Goodman KW. Treatment of infertility in men with spinal cord injury: medical progress and ethical considerations. Top Spinal Cord Inj Rehabil. 2008; 13: 120-33. 4. Burns AS, Rivas DA, Ditunno JF. The management of neurogenic bladder and sexual dysfunction after spinal cord injury. Spine. 2001; 26:S129. 5. Deforge D, Blackmer J, Garritty C, Yazdi F, Cronin V, Barrowman N, et al. Male erectile dysfunction following spinal cord injury: a systematic review. Spinal Cord. 2005; 44:465-73. 6. Shafik A, Shafik AA

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Sexuality of Disabled Athletes Depending on the Form of Locomotion

. Summary of the recommendations on sexual dysfunctions in men. J Sex Med , 2004; 1: 6-23 Meston CM. Validation of the Female Sexual Function Index (FSFI) in women with female orgasmic disorder and in women with hypoactive sexual desire disorder. J Sex Marital Ther , 2003; 29: 39-46 Reitz A, Tobe V, Knapp PA, Schurch B. Impact of spinal cord injury on sexual health and quality of life. Int J Impot Res, 2004; 16: 167-174 Rosen R, Brown C, Heiman J, Leiblum S, Meston C, Shabsigh R, Ferguson D, D'Agostino R Jr. The Female Sexual Function Index (FSFI): a

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Quality of Sexual Life after Microsurgical Penile Denervation in Men with Primary Premature Ejaculation

Summary

Premature ejaculation (PE) is the most common sexual dysfunction in men, yet it is not well studied. Its frequency reaches 30% for men from 18 to 59 years of age in different countries. The aim of this article was to investigate the quality of sexual life in men with primary PE operated on with microsurgical penile denervation, using the Brief Male Sexual Functional Inventory (BMSFI). From September 2011 to March 2014, 22 patients were operated on with microsurgical penile denervation in the urology clinic of the University Hospital - Pleven and the Department of Urology at UMHAT Ruse AD. The mean result from the BMSFI in patients was 22 points preoperatively, indicating significant worsening of sexual function and quality of life in all five questionnaire domains. After surgery, the results increased to 28, 33 and 39 respectively, at 3, 6 and 12 months, respectively. Premature ejaculation not only leads to problems in controlling ejaculation but also worsens the overall sexual function and quality of life of patients.

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Efficacy of vortioxetine monotherapy compared with combined therapy vortioxetine and olanzapine in the treatment of major depression – first results

References [1] Alvarez E, Perez V, Artigas F. Pharmacology and clinical potential of vortioxetine in the treatment of major depressive disorder. Neuropsychiatric Disease and Treatment. 2014;10:1297–1307. [2] Farsky I, Smetanka A, Dubinska S. Spiritualita pacientov s vybranymi psychiatrickymi diagnozami. Osetrovatelstvi a porodni asistence. 2012;3(3):433–441. [3] Nemeroff CB. Prevalence and management of treatment resistant depression. J Clin Psychiatry. 2007;68(Suppl 8):17–25. [4] Serreti A, Chiesa A. Treatment-emergent sexual dysfunction

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Acute phase of depression treatment - current research and its perspectives on Jessenius Faculty of Medicine

. Pharmacology & Therapeutics. 2015;145:43-57. [11] Serretti A, Chiesa A. Treatment-emergent sexual dysfunction related to antidepressants: a meta-analysis. J ClinPsychopharmacol. 2009;29(3):259-266. [12] Tonhajzerova I, Ondrejka I, Chladekova Let al. Heart rate time irreversibility is impaired in adolescent major depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 2012;39(1):212-217.

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The Sexual Satisfaction Questionnaire – psychometric properties

References Arrington, R., Cofrances, J., Wu, A. (2004). Questionnaires to measure sexual quality of life. Quality of Life Research, 13, 1643-1658. Basson, R., (2000) The female sexual response: A different model. Journal of Sex & Marital Therapy, 26, 51-65. Basson, R., Brotto, L., Laan E., Redmond G., Utian, W. (2005). Assessment and Management of Women’s Sexual Dysfunctions: Problematic Desire and Arousal, Journal of Sex Medicine. 2, s. 291-300. Bancroft, J. (2009). Seksualność człowieka

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The quality of sexual life of women with menopause

kompleksowego postępowania terapeutycznego w zaburzeniach nastroju oraz dysfunkcjach seksualnych u kobiet w okresie okołomenopauzalnym. Prz Ginekol Położ. 2007;(4-6):173-82. 9. Ziaei S, Moghasemi M, Faghihzadeh S. Comparative effects of conventional hormone replacement therapy and tibolone on climacteric symptoms and sexual dysfunction in postmenopausal women. Climacteric. 2010;13:147-56. 10. Bińkowska M, Jakiel G. Terapia hormonalna okresu menopauzy – przez skórna droga podania. Prz Menopauzalny. 2012;4:281-6. 11. Norwitz E, Schorge J. Położnictwo i

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Effect of Transdermal Testosterone or Alpha-Lipoic Acid on Erectile Dysfunction and Quality of Life in Patients with Type 2 Diabetes Mellitus / Эффект применения трансдермального тестостерона или альфа-ли- поевой кислоты на эректильную дисфункцию и качество жизни пациентов со сахарным диабетом типа 2

:127-32 (Bulgarian). 21. Hänninen J, Takala J, Keinänen-Kiukaanniemi S. Good continuity of care may improve quality of life in Type 2 diabetes. Diabetes Res Clin Pract 2001;51(1):21-7. 22. Misra R, Lager J. Predictors of quality of life among adults with type 2 diabetes mellitus. J Diabetes Complications 2008;22(3):217-23. 23. Popov S. Sexual dysfunctions in men - diagnostic and psychosocial aspects. [dissertation] Plovdiv: Medical Universtiy-Plovdiv;2011:55-57 (Bulgarian).

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