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References 1. Farmer JJ. 3rd Vibrio (“Beneckea”) vulnificus, the bacterium associated with sepsis, septicemia, and the sea. Lancet 1979; 2: 903. 10.1016/S0140-6736(79)92715-6 2. Hsueh PR, Lin CY, Tang HJ, Lee HC, Liu JW, Liu YC, et al. Vibrio vulnificus in Taiwan. Emerg Infect Dis. 2004; 10:1363-8. 3. Liu JW, Lee IK, Tang HJ, Ko WC, Lee HC, Liu YC, et al. Prognostic factors and antibiotics in Vibrio vulnificus septicemia. Arch Intern Med. 2006; 166: 2117-23. 4. Haq SM, Dayal HH. Chronic liver disease and consumption of raw oysters: a potentially lethal

Abstract

Introduction. The first minutes and hours after birth decide about the quality of human health and further development. Neonatology is intended to optimally lead children through this period, especially the weakest ones.

Aim. The aim of this project is an estimation of sepsis (septicemia) in infants treated in Intensive Care Unit (ICU) in 2 periods, and an attempt to answer what was the cause of infections, as well as comparison of infection causes in infants in the interval of 10 years.

Material and methods. All infants taken to the Intensive Care Unit of the Paediatric Centre at the Central Teaching Hospital of the Medical University of Łodz, in the periods from March 2002 to February 2003 and from January 2013 to December 2013 are included to the study (retrospective). Children taken into consideration had to meet the following criteria: body mass below 2500 grams; first 48 hours of life; infants who stayed in ICU at least 3 days.

Abstract

Indian crested porcupine (Hystrix indica) is a member of the family of Old World porcupines (Hystricidae). Its body is covered with multiple layers of quills, which serve for warning and attack if animal is threatened. However, the literature data on injuries caused by Indian crested porcupine are absent. We describe pathomorphological lesions in an Indian crested porcupine from the Ljubljana Zoo, which died after a fight with a younger male that caused a perforative quill injury of the thoracic wall, followed by septicaemia. Macroscopic, microscopic and bacteriological findings were detailed.

Abstract

Background: Klebsiella rhinoscleromatis is the etiologic bacterium of rhinoscleroma. While rare, it has been implicated as a cause of septicemia. Only five cases of septicemia due to K. rhinoscleromatis have been reported previously. Objective: Report a case of K. rhinoscleromatis septicemia in Thailand and literature review. Results: K. rhinoscleromatis septicemia was observed in a 71-years-old-female diabetic patient suffering with acute fever.

Abstract

Background: Melioidosis is an emerging infectious disease in Southeast Asia. It is an under diagnosed and under reported disease in India mostly because of lack of awareness.

Objective: We studied the clinical profile and outcome of melioidosis.

Methods: A prospective observational study conducted at Kasturba Hospital, Manipal University from May 2007 to July 2009.

Results: There were 31 diagnosed patients in all. Diabetes mellitus was the most common risk factor (68%). Eighty-one percent of cases were detected in the rainy season. Male to female ratio was 3:1. The median age was 48 years. Fifty-two percent of patients were in the age group 41 to 60 years. Thirty-two of patients were agriculturists. Respiratory symptoms were the predominant presentations. The majority (87%) of patients had fever. The bacteria were sensitive to ceftazidime, cotrimoxazole, carbapenems, piperacillin, doxycycline, and chloramphenicol, and resistant to aminoglycosides. Forty-eight percent of patients had bacteremia. Forty-five percent of cases were cured. Twenty-percent of patients had septicemia and septic shock. Sixteen percent of patients died because of septic shock.

Conclusion: Melioidosis is very difficult disease to diagnose clinically and to treat; mostly because of varied presentations. Awareness of the existence of this disease in an endemic region with various underlying risk factors is essential for successful treatment. The early use of appropriate antibiotics and the efficient care of patients with sepsis improves outcomes dramatically. Patients with septicemia and septic shock still result in high mortality rates in spite of efficient critical care.

Abstract

This retrospective study aims to analyze the relationship between biochemical changes occurring in newborns with sepsis proven by positive blood culture (BC) and possible correlations with 1 min Apgar score, 5 min Apgar score, gestational age (GA), and birth weight (BW). We included in the study all infants ≤7 days of life with positive BC that were admitted to the Neonatal Intensive Care Unit (NICU) and Neonatology Department (ND) of the County Emergency Clinical Hospital of Târgu Mureş, a tertiary level hospital, between 2014-2018. The analyzed parameters are: day of life for blood sampling (0-7 days of life), gender, Apgar score (1 and 5 minute), GA, BW, urea, creatinine, total bilirubin, direct bilirubin, aspartate aminotransferase (AST/GOT), alanine aminotransferase (ALT/GPT), c-reactive protein (CPR), bacteria involved, empiric antibiotics administered before blood sampling, temperature of the newborn on the day of BC. We found there is a statistically significant negative correlation between 1 and 5 min Apgar score and creatinine, between GA and urea and also between BW, GA and Direct Bilirubin. We found a statistically significant positive correlation between BW, GA and GPT.

References 1. Linkin DR, Fishman NO, Patel JB, Merrill JD, Lautenbach E. Risk factors for extended-spectrum beta-lactamase-producing Enterobacteriaceae in a neonatal Intensive care unit. Infect Control Hosp Epidemiol. 2004; 25:781-3. 2. Marrie TJ, Durrant. Review of pulmonary and extrapulmonary manifestation of infection due to Coxiella burnetii. Eur Respire J. 1989; 21:713-9. 10.1183/09031936.03.00099703 3. Calderwood DA. Survey of septicemia in intensive care unit. Pediatr Infect Dis J. 1993; 41:56-64. 4. Liberman RP, Wallace CJ, Blackwell CA. Innovations in

- Fish Shellfish Immunol. 28: 613-621. Noya M., Magarińos B., Toranzo A.E., Lamas J. 1995 - Sequential pathology of experimental pasteurellosis in gilthead seabream Sparus aurata. A light and electron- microscopic study - Dis. Aquat. Org. 21: 177-186. Padros F., Zarza C., Dopazo L., Cuadrado M., Crespo S. 2006 - Pathology of Edwardsiella tarda infection in turbot, Scophthalmus maximus (L.) - J. Fish Dis. 29: 87-94. Pirarat N., Maita M., Endo M., Katagiri T. 2007 - Lymphoid apoptosis in Edwardsiella tarda septicemia in tilapia, Oreochromis niloticus - Fish Shellfish

controversial because some cases are caused from severe infection and may this increase mortality. However, some case reports have shown the benefit of corticosteroids in reducing epidermal loss when given early in the course of the disease [ 3 , 4 ]. Other treatments have been used include intravenous immunoglobulin (IVIG), tumor necrosis factor-a inhibitors, cyclosporin, cyclophosphamide, plasmapheresis, and hemodialysis [ 3 ]. Acute complications frequently found in SJS/TEN are secondary skin infections because of the detachment of skin, pneumonia, septicemia, hepatitis

Clinical outcomes of acute diarrhea During 1 year of follow-up, there were deaths in 1,048 admissions (0.5%). The mortality rate of patients in the UC and the CSMBSE group was higher than that for patients in the SSF group (0.6%, 0.6% vs 0.1%). The complications encountered during hospitalization were septicemia (n = 4675; 2.2%), on mechanical ventilation (n = 1249; 0.6%), and renal failure requiring hemodialysis (n = 294; 0.14%). The HIV infection rate was 1.4%. The mean length of hospital stay was 2.5 days. The patients who stayed in the hospital longer than 3 days