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longer. As a result, CV events increase over time, together with the costs of treatment of these diseases. Despite the proven efficacy, the limited availability of resources is of concern. As the use of n-3 PUFAs is approved as supplemental treatment in secondary prevention after MI in addition to other standard therapies, this study aimed to assess the cost-effectiveness of adding highly concentrated n-3 PUFAs to the current treatment in post-MI patients in Thailand. Methods Model structure A Markov model was developed in Excel version 2013, starting with the event


Atrial fibrillation is one of major risk factors of cerebral infarction. The use of oral anticoagulants is the only evidence-based method of reducing the risk of cardioembolic accidents. The guidelines of oral anticoagulant admission and usage have been available since 2012. The results of this study show that of 550 stroke patients that were admitted to Pauls Stradiņš Clinical University Hospital, Rīga, Latvia, from 1 January 2014 until 1 July 2014, atrial fibrillation was diagnosed in 247 (45%) cases, and of these patients, only 8.5% used oral anticoagulants before the onset of stroke. Six months after discharge of 111 (44.9%) stroke survivors, five (4.5%) used no secondary prevention medication, 27 (24.3%) used antiplatelet agents, 54 (48.6%) warfarin, and 25 (22.5%) used target specific oral anticoagulants (TSOACs). The mortality rate was significantly higher in the patient group that used no secondary prevention medication or antiplatelet agents compared to the patient group that used oral anticoagulants. The use of oral anticoagulants for primary stroke prevention in Latvia is insufficient. The mortality of cardioembolic stroke in 180 days is very high - 40.4%. Secondary prevention is essential to prevent recurrent cardioembolic accidents.


Aim. To determine the influence of socio-demographic variables on attendance rate at screening examinations in cancer patients. Material and methods. The research group comprised of 100 cancer patients. The method applied in the research was a diagnostic survey. The research instrument was the authors‘ own questionnaire specially compiled to measure cancer patients‘ interest in screening examinations. The research material was analysed with the statistical packet STATISTICA 12 and Microsoft Office Excel software. Significance level was assumed at p<0.05 to determine statistically significant differences and dependencies. A Chi2 test was used in the research. Results. The surveyed patients mostly did not participate in screening examinations aimed at diagnosing cancer (66%). Their Age (p=0.05), gender (p=0.003) and place of residence (p=0.04) determined their participation rate in screening tests. The patients‘ marital status (p=0.47), education (p=0.85) and economic status (p=0.13) did not affect their willingness to attend screening examinations. Conclusions. The process of cancer incidence and death rate limitation requires greater participation of the population in prevention programmes.

Obvladovanje Tobaka in Alkohola V Zdravstvenem Domu Logatec

Za preventivo na področju tobaka in alkohola so odločilnega pomena ukrepi na ravni družine in lokalne skupnosti. V članku so prikazane dejavnosti v Zdravstvenem domu Logatec ob takšnem razumevanju dejavnikov tveganja. Raziskava zajema pregled izsledkov nekaterih dejavnosti na področju tobaka in alkohola, posebej načrtovanih za preventivo v zadnjih treh letih. Potrjuje, da si za to vsaj nekoliko prizadevajo vse službe zdravstvenega doma: otroški in šolski dispanzerji ter ambulante družinske medicine, in sicer v okviru specifičnih preventivnih dejavnostih iz programa CINDI, v okviru posebnih dejavnosti za splošno populacijo in v okviru tistih, ki so oblikovane posebej za bolnike Centra za preventivo in zdravljenje odvisnosti od prepovedanih drog.

decide on an individual patient basis whether or not to initiate statins in ESRD. A statin may be justified for secondary prevention of cardiovascular events, in patients with longer life expectancies, and in non-diabetics.[ 41 , 43 ] Conclusions Large well-conducted RCTs did not demonstrate any benefit of pre- or peri-operative statin treatment in patients undergoing various types of cardiac surgery. For unknown reasons, statins may even harm the kidneys in this particular patient population. A potential renal protective effect of preoperative statin therapy after

powyżej patologii. Badanie to oznaczono w skrócie jako SURVET = The Sulodexide in Secondary Prevention of Recurrent Deep Vein Thrombosis.: “Sulodeksyd w zapobieganiu nawrotom zakrzepicy żył głębokich” (ZŻG) - badanie wielośrodkowe, randomizowane, podwójnie zaślepione, z kontrolą placebo [ 4 ]. Do badania tego zrandomizowano 617 chorych z przebytym niedawno pierwszym epizodem niesprowokowanej ZŻG w odcinku proksymalnym lub zatorowością płucną (ZP). Wszyscy chorzy ukończyli leczenie przeciwkrzepliwe, trwające zgodnie z wytycznymi od 3 do 12 miesięcy i zgłaszali chęć

is not feasible, except in Japan and Korea. 5 , 6 In Western countries, regular endoscopic follow-up is offered to patients with endoscopically visible preneoplastic lesions according to MAPS recommendations 7 , 8 , but this represents only opportunistic secondary prevention. Serologic biopsy – measuring pepsinogen I and pepsinogen II (PGI, PGII), Gastrin 17 (G 17) and H. pylori antibodies in the serum can select those patients with preneoplastic gastric lesions. In case of corpus atrophy and intestinal metaplasia, the production of pepsinogen I goes down more


Biomedical HIV prevention strategies for primary or secondary prevention of HIV transmission can be seen as an adjunct to behavioral prevention approaches. These interventions include vaccination, female controlled vaginal microbicides, male circumcision, treatment of sexually transmitted infections that cause genital ulceration, Pre-Exposure Prophylaxis (PREP) and Post-Exposure Prophylaxis (PEP). This article reviews results from recent randomized controlled trials of novel biomedical prevention approaches and discusses interpretation of the results. The only intervention consistently demonstrating reductions in HIV transmission was adult male circumcision in Sub-Saharan Africa. Results of PREP trials will be available in the next several years.


Physical activity is interrelated with health, physical fitness, and quality of life. The role physical activity plays in the context of lifestyle disease prevention is indisputable. Physical exercises of yoga (hatha yoga) are a type of recreational physical activity classified as a form of body and mind fitness. Hatha yoga training consists of slow or fast and smooth entering into, holding, and exiting yoga postures called “asanas”. Besides asanas, a yoga class may also include breathing exercises (pranayama) and relaxation exercises. The aim of this paper is to analyse the benefits of regular hatha yoga training in the light of scientific studies in regard to primary and secondary prevention of lifestyle diseases (cardiovascular diseases, respiratory system diseases, type 2 diabetes, obesity, and diseases of the musculoskeletal system in particular). The results of the analysis revealed that regular hatha yoga training including pranayama (breathing exercises) produced a reduction in blood pressure and heart rate, improved respiratory functions, decreased blood glucose levels and body mass, as well as improving functional fitness and self-perceived quality of life. Therefore, hatha yoga as a form of physical activity can be a useful intervention for primary and secondary prevention of cardiovascular diseases, respiratory system diseases, metabolic diseases, and diseases of the musculoskeletal system, including back pain.


This is a case report of a 36-year-old male who was diagnosed with acute inferior and right ventricular myocardial infarction and treated with percutaneous coronary angioplasty with a drug-eluting stent in the right coronary artery. A profile test for thrombophilia was performed for methylene tetrahydrofolate reductase (MTHFR) gene mutation; the test was positive for a heterozygous mutation - C677C and 1298A. The patient received a long-term treatment with folic acid supplements, taken daily. This case report shows that medical doctors should have an outside-the-box approach for the diagnosis and therapeutic management of young patients who present with acute cardiovascular events. If the patient in question does not present clear cardiovascular risk factors for acute myocardial ischemia, the clinician should seek for possible causes, thus leading to several benefits in the management and secondary prevention of such cases.