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–1416. Balasundram, N., Sundram, K., Samman, S. (2006). Phenolic compounds in plants and agri-industrial by-products: Antioxidant activity, occurrence, and potential uses. J. Food Chem., 99 (1), 191–203. Chantaro, P., Devahastin S., Chiewchan, N. (2008). Production of antioxidant high dietary fiber powder from carrot peels. J. Food Sci. Technol. , 41 , 1987–1994. Daayf, F., Lattanzio, V. (2008). Recent Advances in Polyphenol Research. Vol. 1. Wiley-Blackwell. 437 pp. Fraga, C. G. (2009). Plant Phenolics and Human Health: Biochemistry, Nutrition, and Pharmacology. John

References Aengwanich W., Suttajit M. (2010). Effect of polyphenols extracted from Tamarind (Tamarindus indica L.) seed coat on physiological changes, heterophil/lymphocyte ratio, oxidative stress and body weight of broilers (Gallus domesticus) under chronic heat stress. Anim. Sci. J., 81: 264-270. Akbarian A., Golian A., Kermanshahi H., Farhoosh R., Raji A.R., De Smet S., Michiels J. (2013). Growth performance and gut health parameters of finishing broilers supplemented with plant extracts and exposed to daily increased temperature. Span. J. Agric. Res., 11

activation. Biochemistry 41 : 7743-7750. Fraga CG, Galleano M, Verstraten S, Oteiza PI. (2010). Basic biochemical mechanisms behind the health benefi ts of polyphenols. Mol Asp Med 31 : 435-445. Franck T, Kohnene S, Grulke S, Neven, P, GoutmanY, Peters F, Pirotte B, Deby-Dupont G, Serteyn D.(2008). Inhibitory eff ect of curcuminoids and tetrahydrocurcuminoids on equine activated neutrophils and myeloperoxidase activity. Physiol Res 57 : 577-587. Jančinova V, Drabikova K, Nosaľ R, Račkova L, Majekova M, Holomańova D.(2006). The combined luminol

. Pires de Oliveira, Effect of polyphenols from Campomanesia adamantium on platelet aggregation and inhibition of cyclooxygenases: Molecular docking and in vitro analysis, Front. Pharmacol. 9 (2018) 617 (13 pages); 44. A. Mira, W. Alkhiary and K. Shimizu, Antiplatelet and anticoagulant activities of Angelica shikokiana extract and its isolated compounds, Clin. Appl. Thromb. Hemost. 23 (2017) 91–99; 45. A. A. Boligon, V. C. Pimentel, M. D. Bagatini and M. L. Athayde, Effect of

incidence and mortality worldwide for 36 cancers in 185 countries, CA-Cancer J. Clin. 68 (2018) 394–424; 5. T. Nabekura, Overcoming multidrug resistance in human cancer cells by natural compounds, Toxins 2 (2010) 1207–1224; 6. M. Fantini, M. Benvenuto, L. Masuelli, G. Frajese, I. Tresoldi, A. Modesti and R. Bei, In vitro and in vivo antitumoral effects of combinations of polyphenols, or polyphenols and anticancer drugs: perspectives on cancer treatment, Int. J. Mol. Sci. 16 (2015) 9236

REFERENCES 1. Bai W., Wang C., Ren C., Intakes of total and individual flavonoids by US adults. Int. J. Food Sci. Nutr., 2014, 65, 9–20. 2. Balentine D.A., Dwyer J.T., Erdman J.W., Jr., Ferruzzi M.G., Gaine P.C., Harnly J.M., Kwik-Uribe C.L., Recommendations on reporting requirements for flavonoids in research. Am. J. Clin. Nutr., 2015, 101, 1113–1125. 3. Bohn T., Dietary factors affecting polyphenol bioavailability. Nutr. Rev., 2014, 72, 429–452. 4. Brat P., George S., Bellamy A., Du Chaffaut L., Scalbert A., Mennen L., Arnault N., Amiot M.J., Daily polyphenol

the longevity rather than a single nutrient in the diet, with a significant reduction in the overall mortality.[ 17 ] This assumption is a cornerstone for public health, and in particular, in the context of prevention policy based on the Mediterranean style in the primary prevention of major chronic diseases not only in Western Countries, but also in all urban area worldwide.[ 18 ] Polyphenols And Nafld Polyphenols are a heterogeneous class of plant derived compounds, that include several hydro soluble antioxidants reported as health promoting agents and proposed in

polyphenol (-)-epigallocatechin gallate attenuates β-amyloid-induced neurotixicity in cultured hippocampal neurons. Life Sci., 2001, 70, 603-614. 7. Duchnowicz P., Broncel M., Podsędek A., Koter-Michalak M., Hypolipidemic and antioxidant effects of hydroxycinnamic acids, quercetin, and cyanidin 3-glucoside in hypercholesterolemic erythrocytes (in vitro study). Eur. J. Nutr., 2012, 51, 435-443. 8. Ellman G.L., Lourtney D. K., Andres V., Gmelin G., A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem. Pharmacol., 1961, 7, 88-95. 9. Ferk F

., Velchev Z., Dinkov H. & Mollov P. (2012). Changes in the total anthocyanins and polyphenols during processing of wild berries into freshly pressed juices. Journal of EcoAgriTourism, 8(1), 254−259. 7. Dixit N., Tripathi C. & Upadhyay R. (1976). The antifungal substance of rose flowers (Rosa indica). Econ. Bot., 30, 371−374. DOI:10.1007/BF02904658. 8. Dobrev G. & Zhekova B. (2012). Biosynthesis, purification and characterization of endodlucanase from xylanase, produsing strain Aspergilus niger B03. Brazilian Journal of Microbiology, 43(1), 70−77. DOI: 10.1590/S1517

polyphenol-rich foods: an open clinical trial. J Perinatol 2012, 32 (8): 574-9 82. Mielke G and Benda N.: Reference ranges for two-dimensional echocardiographic examination of the fetal ductus arteriosus. Ultrasound Obstet Gynecol 2000, 15 (3) : 219-225 83. Tulzer G, et al.: Doppler echocardiography of fetal ductus arteriosus constriction versus increased right ventricular output. J Am Coll Cardiol 1991, 18 (2): 532-6 84. Van den Hoff MJ, et al.: Increased cardiac workload by closure of the ductus arteriosus leads to hypertrophy and apoptosis rather than to hyperplasia in