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References 1. Asuncion M, Calvo RM, San Millan JL, Sancho J, Avila S, Escobar-Morreale HF. A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain . J Clin Endocrinol Metab 85: 2434-2438, 2000. 2. Knochenhauer ES, Key TJ, Kahsar-Miller M, Waggoner W, Boots LR, Azziz R. Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study . J Clin Endocrinol Metab 83: 3078-3082, 1998. 3. Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES

References 1. Rotterdam ESHRE / ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risk related to polycystic ovary syndrome. Fertil. Steril. 2004; 81 (1): 19-25. 2. National Institutes of Health Evidence-based methodology workshop on polycystic ovary syndrome, December 3-5, 2012. Executive summary. https://prevention.nih.gov/docs/programs/pcos/FinalReport.pdf . 3. Fauser BC, Tarlatzis BC, Rebar RW, Legro RS, Balen AH, Lobo R, et al. Consensus on women’s health aspects of polycystic ovary syndrome

References 1. Diamanti-Kandarakis E, Kouli CR, Bergiele AT et al . A survey of the polycystic ovary syndrome in the Greek island of Lesbos: hormonal and metabolic profile. J Clin Endocrinol Metab 84: 4006-4011, 1999. 2. Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO . The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab 89: 2745-2749, 2004. 3. March WA, Moore VM, Willson KJ, Phillips DI, Norman RJ, Davies MJ . The prevalence of polycystic ovary syndrome in a community sample assessed

References 1. Gurunath S, Pandian Z, Anderson RA et al. Defining infertility--a systematic review of prevalence studies. Hum Reprod Update. 2011; 17(5): 575-588. 2. Łepecka-Klusek C, Pilewska-Kozak AB, Jakiel G. Infertility - a disease or not according to the WHO definition. Med Og Nauk Zdr. 2012; 18(2): 163-166. 3. Shannon M, Wang Y. Polycystic Ovary Syndrome: A common but often unrecognized condition. J Midwifery Women’s Health. 2012; 57(3): 221-230. 4. Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group. Consensus on women’s health aspects of

References 1. Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab 89: 2745-2749, 2004. 2. Asuncion M, Calvo RM, San Millan JL et al. A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain. J Clin Endocrinol Metab 85: 2434-2438, 2000. 3. Diamanti-Kandarakis E, Kouli CR, Bergiele AT et al. A survey of the polycystic ovary syndrome in the Greek island of Lesbos: hormonal and

Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies, with a prevalence of approximately 10% among women of a reproductive age [ 1 ]. Insulin resistance (IR) is considered a main feature of women with PCOS. Consequently, these patients are at a higher risk of having type 2 diabetes mellitus (DM) and metabolic syndrome [ 2 , 3 , 4 , 5 , 6 ]. Early diagnosis of PCOS may facilitate early detection of metabolic disorders, which may help to prevent long-term metabolic sequelae. The etiology of PCOS remains unknown. Diagnosis of PCOS is currently

References 1. Ehrmann DA. Polycystic ovary syndrome. N Engl J Med. 2005; 352:1223-36. 2. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod. 2004; 19:41-7. 3. Cheung AP. Ultrasound and menstrual history in predicting endometrial hyperplasia in polycystic ovary syndrome. Obstet Gynecol. 2001; 98:325-31. 4. Giudice LC. Endometrium in PCOS: implantation and predisposition to endocrine CA. Best Pract Res Clin Endocrinol Metab. 2006; 20:235-44. 10.1016/j.beem.2006.03.005 5. Iatrakis G

References 1. Conway G, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Franks S, Gambineri A et al. The polycystic ovary syndrome: a position statement from the European Society of Endocrinology. European Journal of Endocrinology 2014; 4 1-29. DOI: 10.1530/EJE-14-0253 2. Wang R, Mol BW. The Rotterdam criteria for polycystic ovary syndrome: evidence-based criteria? Hum Reprod. 2017 Feb; 32(2):261-4. DOI: 10.1093/humrep/dew287 3. Gambineri A, Pelusi C, Vicennati V, Pagotto U, Pasquali R. Obesity and the Polycystic Ovary Syndrome. Int J Obes Relat Metab

Irodalom 1. Escobar-Morreale HF. Polycystic ovary syndrome: Definition, aetiology, diagnosis and treatment. Nature Reviews Endocrinology. Nature Publishing Group; 2018. p. 270–84. 2. Nybacka Å, Hellström PM, Hirschberg AL. Increased fibre and reduced trans fatty acid intake are primary predictors of metabolic improvement in overweight polycystic ovary syndrome—Substudy of randomized trial between diet, exercise and diet plus exercise for weight control. Clinical Endocrinology. Blackwell Publishing Ltd; 2017;87:680–8. 3. Borsos A, Jakab A. Polycysticus ovarium

References Al-Eisa E, Gabr SA, Alghadir AH. Effects of supervised aerobic training on the levels of anti-Mullerian hormone and adiposity measures in women with normo-ovulatory and polycystic ovary syndrome. J Pak Med Assoc 67, 499-507, 2017. Arner P. Human fat cell lipolysis: biochemistry, regulation and clinical role. Best Pract Res Clin Endocrinol Metab 19, 471-482, 2005. Artimani T, Karimi J, Mehdizadeh M, Yavangi M, Khanlarzadeh E, Ghorbani M, Asadi S, Kheiripour N. Evaluation of pro-oxidant-antioxidant balance (PAB) and its association with inflammatory