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intelligence approach to safe ship control. Polish Maritime Research, 2015, Vol. 22, Issue 4, pp. 34-40. 7. Lebkowski A.: 3D navigator decision support system using the smart glasses technology. Edited by Weintrit A., Neumann T.: Information, communication and environment - marine navigation and safety sea transportation, 2015, pp. 117-122. 8. Lisowski J.: Game control methods in avoidance of ships collisions. Polish Maritime Research, 2012, Vol. 19, Special Issue, pp. 3-10. 9. Lisowski J.: Optimization methods (in Polish). Wydawnictwo Akademii Morskiej w Gdyni, 2017. 10

. (1981). Maximizing the Variance of M-Estimators Using the Generalized Method of Moment Spaces. The Annals of Statistics , 567-577. Retrieved from Dragomirescu, M., & Malița, M. (1972). Programare neliniară. Bucureşti: Ed. Ştiinţifică. Fedorov, V. (1996). 16 Design of spatial experiments: Model fitting and prediction. Handbook of Statistics , 515-553. Retrieved from Gentle, J. E. (2006). Optimization Methods for Applications in

. B. Chávez, “Optimization Methods for Switched Capacitor Circuits,”, International Conference on Applied Electronics. 2015, Plzeň pp.165–168, 8-9 September 2015, ISSN 1803-7232, ISBN 978-80-261-0385-1. [23] J. Nahlik, J. Hospodka and O. Šubrt, “SC Filter Optimization Performance by Hybrid Simplex Algorithm”, 2018 15th International Conference on Synthesis , Modeling, Analysis and Simulation Methods and Applications to Circuit Design (SMACD), Praha, pp.285-288, 2-5 July 2018, ISBN 978-1-5386-5152-0.


At present, concentrations of pharmaceuticals in surface and ground waters are low; however, even low concentrations of certain substances may prove very harmful. One of such pharmaceutical drugs is diclofenac, a popular non-steroidal anti-inflammatory drug (NSAID). For this reason, it is important to determine its mobility in groundwater and to estimate parameters of migration. Authors conducted column tests for two porous media: an artificial one, consisting of glass granules, and a natural one, i.e., sandur sand obtained from a site north of the city of Poznań (Poland). During the test, impulse breakthrough curves of chloride ions and diclofenac were recorded. The results were used to identify a specific sorption model and to determine values of migration parameters. Solutions of the inverse problem using optimisation methods and of equations of mathematical migration models were carried out in a MATLAB environment. Based on test results, the mobility of diclofenac is shown to be very high and comparable to that of chloride ions. The tests also revealed a slight and irreversible sorption of diclofenac on grains of both porous media.


Full-film hydrodynamic lubrication of marine propulsion shafting journal bearings in running condition is discussed. Considerable computational difficulties in non-linear determining the quasi-static equilibrium of the shafting are highlighted. To overcome this problem the approach using two optimization methods (the particle swarm method and the interior point method) in combination with the specially developed relaxation technique is proposed. The developed algorithm allows to calculate marine propulsion shafting bending with taking into account lubrication in all journal bearings and exact form of journal inside bearings, compared to results of most of the publications which consider lubrication only in the aft most stern tube bearing and assume rest of bearings to be represented by points. The calculation results of typical shafting design with four bearings are provided. The significance of taking into account lubrication in all bearings is shown, specifically more exact values of bearings’ reactions, shafting deflections, minimum film thickness and maximum hydrodynamic pressure in the stern tube bearing in case of considering lubrication in all bearings.


The algorithm for maximum power point tracking (MPPT) using a fixed is widely used because of its simplicity and easyness to implement. This paper presents an improvement consisting in a variable step (VS) applied to the standard Hill Climbing MPPT technique to improve both accuracy and tracking speed. Drawbacks will still be encountered in VS tracking algorithms, between response time and power oscillation.


Multilateration measurement using laser trackers suffers from a cumbersome solution method for high-precision measurements. Errors are induced by the self-calibration routines of the laser tracker software. This paper describes an optimization solution model for laser tracker multilateration measurement, which effectively inhibits the negative effect of this self-calibration, and further, analyzes the accuracy of the singular value decomposition for the described solution model. Experimental verification for the solution model based on laser tracker and coordinate measuring machine (CMM) was performed. The experiment results show that the described optimization model for laser tracker multilateration measurement has good accuracy control, and has potentially broad application in the field of laser tracker spatial localization.

-based optimization algorithm, International Journal of Bio-Inspired Compu- tation (IJBIC), 1 (1/2), (2009), 71-79 [12] A. Kaveh and S. Talatahari, A Novel Heuristic Optimization Method: Charged System Search, Acta Mechanica, 213, (2010), 267-289 [13] J. D. Pintér, Global Optimization: Software, Test Problems, and Applications, Ch. 15 in Handbook of Global Optimization, Volume 2 (Ed. P. M. Pardalos and H. F. Romeijn), Kluwer Academic Publishers, Dordrecht, Boston, London, 2002 [14] R. Horst and P.M. Pardalos, Handbook of Global Optimization, Kluwer Academic Publishers, Dordrecht

the Context of Environmental Protection. Baltic Journal of Road and Bridge Engineering , 11 (2), 160-168. doi:10.3846/bjrbe.2016.19 Rekiek, B., Dolgui, A., Delchambre, A., & Bratcu, A. (2002). State of art of optimization methods for assembly line design. Annual Reviews in Control , 26 (2), 163-174. Ryan, J., & Heavey, C. (2006). Process modeling for simulation. Computers in Industry , 57 , 437-450. Sa’udah, N., Amit, N., & Ali, M. N. (2015). Facility Layout for SME Food Industry via Value Stream Mapping and Simulation. Procedia Economics and Finance , 31


The goat (Capra hircus) is a perfect animal model for analyzing the transcriptome of milk somatic cells (MSCs), as sufficient numbers of somatic cells in goat milk, i.e., exfoliated epithelial cells, can be obtained using noninvasive methods. RNA integrity and purity are the first and most important parameters qualifying samples for transcriptomic tests and next-generation sequencing, as RNA quality influences experimental results. The aim of this study was to optimize a method for obtaining high-quality RNA from goat MSCs, irrespective of effects like breed, lactation stage, health status (e.g., with or without small ruminant lentivirus [SRLV] infection), or number of somatic cells. Milk samples were obtained from goats of two Polish breeds in various lactation stages and in different parities, and from goats infected and not infected with SRLV. Altogether, 412 MSC samples were examined: 206 using method A with fenozol and 206 using method B with QIAzol. Though the overall purity (measured as absorbance ratios at 260 nm/280 nm and 260 nm/230 nm) of the RNA material was comparable, the average yield of RNA isolated using method A was 11.9 µg, while method B’s average yield was 29.9 µg. Moreover, method B resulted in good quality RNA suitable for transcriptome analysis. Results were confirmed by RT-qPCR, using 18S rRNA and RPLP0 as the reference genes. The application of our modified treatment method was successful in obtaining high-integrity samples for transcriptomic or next-generation sequencing analysis. Using a 400 mL milk sample cooled in ice directly after milking, securing the cooling chain process from milking to MSC isolation, and applying method B to isolate RNA, we obtained good RNA quality irrespective of the goats’ breed, lactation stage, parity, milk yield, SRLV infection, and even milk yield and number of somatic cells in milk.