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radiation therapy for Hodgkin’s lymphoma: coronary CT angiography findings and calcium scores in nine asymptomatic patients. AJR Am J Roentgenol . 2008;191:32-37. 11. Küpeli S, Hazirolan T, Varan A, et al. Evaluation of coronary artery disease by computed tomography angiography in patients treated for childhood Hodgkin’s lymphoma. J Clin Oncol . 2010;28:1025-1030. 12. Hoffmann MH, Shi H, Schmitz BL, et al. Noninvasive coronary angiography with multislice computed tomography. JAMA . 2005;293:2471-2478. 13. Groarke JD, Nguyen PL, Nohria A, Ferrari R, Cheng S, Moslehi J

-Risk or Vulnerable Atherosclerotic Plaque. Circ Res . 2001;89:305-316. 29. Crouse JR. Thematic review series: Patient-Oriented Research. Imaging atherosclerosis: state of the art. J Lipid Res . 2006;47:1677-1699. 30. Nahrendorf M, Jaffer FA, Kelly KA, et al. Noninvasive Vascular Cell Adhesion Molecule-1 Imaging Identifies Inflammatory Activation of Cells in Atherosclerosis. Circulation . 2006;114:1504-1511. 31. Jaffer FA, Libby P, Weissleder R. Optical and Multimodality Molecular Imaging: Insights Into Atherosclerosis. Arterioscler Thromb Vasc Biol . 2009

maternal plasma and ultrasound. Prenat Diagn 2006, 26: 598-603. Lo Y.M., Tein M.S., Lau T.K., et al. Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis. Am. J. Hum. Genet. 1998; 62: 768-775. Finnig K.M., Chitty L.S.: Non-invasive fetal sex determination: Impact on clinical practice. Seminars Fetal Noenatal Med 2008; 13: 69-75. Lau T.W., Leung T.N., Chan L.Y., et al. Fetal clearance from maternal plasma is impaired in preeclampsia. Clin. Chem. 2002; 48: 2141-2146. Hromadnikova I., Holubova B., Hridelova D. et

complications than those without liver fibrosis [ 7 ]. Liver biopsy is a criterion standard by which to diagnose the severity of liver fibrosis, but it has several limitations for clinical practice including the expense and the invasive nature of the procedure, which is associated with a number of complications [ 8 ]. Patients with NASH showed progression of fibrosis in about 5%-32% during a 4.3-to-6 year follow-up period [ 9 , 10 , 11 ]. Several simple noninvasive scoring systems for assessment of liver fibrosis have been proposed for use in general clinical practice. NAFLD

REFERENCES 1. Rochwerg B, Brochard L, Elliott MW, et al. Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure. Eur Respir J. 2017;50:1602426. 2. Nicolini A, Stieglitz S, Bou-Khalil P, Esquinas A. Cost-utility of non-inasive mechanical ventilation: Analysis and implications in acute respiratory failure. A brief narrative review. Respr Investig. 2018;56(3):207-13. 3. Mandell A, Wunderink R, Anzueto A et al. Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of

Abstract

The determination of gamma dose rates is of prior importance in the field of luminescence dating methods. In situ measurements are usually performed by the insertion of dosimeters or a portable gamma spectrometer cell in sediments. In this paper, Monte-Carlo simulations using the Geant4 toolkit allow the development of a new technique of insitu gamma dose rate evaluations: a spectrometer cell is placed on the surface of sediments under excavation to acquire successive spectra as sediments are removed by excavations. The principle of this non-invasive technique is outlined and its potential is discussed, especially in the case of environments in which radioelements are heterogeneously distributed. For such cases, a simple method to reconstruct gamma dose rate values with surface measurements using an attenuator is discussed, and an estimation of errors is given for two simple cases. This technique appears to be applicable, but still needs experimental validation.

Abstract

The development and studies related to carbon nanotubes, due to their physical properties and small sizes, are revealing new applications in the medical field. The present paper is proposing a non-invasive method of patient glycemia measurement by mean of carbon nanotubes based sensor. Due to their small sizes and elastic properties, carbon nanotubes are able to oscillate under the weight of small molecules capable of fixing on their body structure. After piezoelectric activation, the carbon nanotubes sensor based, is able to detect the variation of oscillations produced in nanotubes due to acetone molecules diffused through a selectively permeable membrane from the exhaled air, and attached to the nanotubes. The mathematical model taken into accont shows a linear dependence between the concentration of acetone in blood and glycemia, and makes the carbon nanotube sensor suitable for indirect estimation of the glycemia by noninvasive measurements made on the exhaled air sample, providing zero risk for the patient and absence of stress during the measurements.

REFERENCES 1. PANDA A, VENKATAPATHY R AND NIRIMA O. Glucose estimation in the salivary secretion of diabetes mellitus patients. Diabetes, Metabolic Syndrome and Obesity . Targets and Therapy 2012; 5 :149-54. 2. ARATI S P. Correlation of salivary glucose level with blood glucose level in diabetes mellitus . J Oral Maxillofac Res 2012; 3 :1-7. 3. AGRAWAL RP, SHARMA N, RATHORE MS, GUPTA VB, JAIN S, AGARWAL V, et al. Noninvasive method for glucose level estimation by saliva . J Diabetes Metab 2013 4 : 266. 4. ANTONELLA, MARCO T, LUIGI F, VALENTINA P, GAETANO I

vitro before their in vivo transplantation ( 3 ). In order to evaluate tissue-engineered constructs, methods should be employed which would be able to provide information regarding the morphological and functional behavior of the cell cultures in a real-time and non-invasive manner ( 5 ). Due to the high costs and small number of donors, the monitoring methods should be ideally non-destructive to the cell cultures. Currently used technique for the purpose of investigating tissue engineered cultures provide helpful information about the characteristics of the tissue

., Dufand, O., Bardin-Monnier, N., Lopez, O., Munoz, F., Perrin, L. (2013). Dust explosions: CFD modeling as a tool to characterize the relevant parameters of the dust dispersion. Chemical Engineering Science, 104, 103-116. [16] Federici, G., Skinner, C.H., Brooks, J.N. et al. (2001). Plasma-material interactions in current tokamaks and their implications for next step fusion reactors. Nuclear Fusion, 41 (12), 1967. [17] Poggi, L.A., Gaudio, P., Rossi, R., Ciparisse, J.F., Malizia, A. (2017). Non-invasive assessment of dust concentration and relative dustiness in a dust