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Modelling the influence of different concentrations of lead and cadmium ions upon a laboratory culture of insects has not been adequately studied. In our research, we assessed the influence of cadmium and lead nitrates at different concentrations (10-2-10-9 М) upon the development of larvae, pupae and imagines of Calliphora vicina Robineau-Desvoidy, 1830 (Diptera: Calliphoridae). We found an acceleration in the development of larvae and an increase in mass of puparia when lead ions were added to the food of the larvae, and decrease in the mass of puparia when cadmium ions were added. We registered nanism and malformation of the fly imagines in experiments with lead and cadmium in the food substrate. We observed that under the influence of the studied heavy metal ions there was a reduced motor activity of the fly larvae at all stages of development, a delay in formation of puparia and a delay in the emergence of imagines in comparison with the control group.

, N.J., Thorne, C. R., Biedenharn, D. S. 2005. Morphological changes of the Lower Mississippi River: Geomorphological response to engineering intervention. River Research Applications 21 (10), 1107-1131. DOI: 10.1002/rra.887 Hooke, J.M. 1995. River channel adjustment to meander cutoffs on River Bollin and River Dane, Northwest England. Geomorphology 14, 235-253. DOI: 10.1016/0169-555x(95)00110-q Huang, M.W., Liao, J.J., Pan, Y.W., Chen, M.H. 2014. Rapid channelization aqnd incision into soft bedrock induced by human activity: Implication from the Bachang River in

model with other used bed load models - effects on river morphological changes, Journal of Water Resources and Ocean Science, 3, 5, 61–68. Gharbi, M., Soualmia, A., Dartus, D., Masbernat, L., 2014b. Analysis of morphological changes in rivers. In: Proc. International conference on fluvial hydraulics: river flow, Lausanne, Switzerland, pp. 1315–1321. Goff, J.R., Ashmore, P., 1994. Gravel transport and morphological change in braided Sunwapta River, Alberta, Canada. Earth Surface Proc and Landforms, 19, 195–212. Goutx, D., Ladreyt, S., 2001. Hydraulique des Cours D

We evaluated the influence of some morphological changes of the NCI-H125 cell line in surface expression of the epidermal growth factor receptor (EGFR) and their impact on some biological activity assays using this molecule as target. Hematoxylin and eosin (H/E) staining, light microscopy immunocytochemistry, flow cytometric antibody-receptor binding test, cell viability determination and cell cycle analysis were performed. Phenotypic changes and inconsistency in EGFR expression were detected in NCI-H125 cell cultures. A significant reduction in the growth rate, mainly characterized by cell cycle arrest in the G0-G1 phase, was also evidenced. Differential distribution of cell viability in NCI-H125 subpopulations and its relationship with the EGFR surface expression were determined. Nuclear alterations observed in NCI- -H125 were not apoptosis related. A lack of control of cell cultures affects the reliability and reproducibility of biomedical and biotechnological research using EGFR as target. Therefore, rigorous control of the above mentioned parameters in these experiments is recommended.


This research focuses on the reconstruction of the morphological modifications of the coastal floodplain of Rapallo (Eastern Liguria, NW Italy) due to human intervention since the eighteenth century. By the second half of the nineteenth century Rapallo became a popular tourist destination: as a consequence, the urban development of the floodplain started and became very intense after Second World War, strongly modifying former landforms.

The study was carried out using multi-temporal cartographic and photographic comparison, the analysis of geo-thematic cartography and documentation from the Basin Master Plan and the town plan of Rapallo, the interpretation of cores from regional database and field data from direct urban surveys. Man-made landforms were mapped and classified using the new geomorphological legend which is in progress in the framework of the Working Groups on “Cartography” and “Urban Geomorphology” of the Italian Association of Physical Geography and Geomorphology (AIGEO).

The main significant morphological changes were stream diversions and channeling, excavations and filling, quarry activities, embankments along the shoreline and overurbanization. Human interventions, in addition to local geomorphological and climate features, increased flood hazard and risk, which historically affected the city of Rapallo.


This research concerns the complex problem of morphological transformations of villages in the intra-urban area (i.e. settlements incorporated into acity), as well as the suburban area, using the example of the metropolitan area of Łódź, Poland. The main aim of the research was to analyse the diversity of selected rural settlements and their spatial changes after World War II.. The study was based on preserved historical maps and today’s plans. An analysis of morphological changes of selected villages was conducted using graph theory methods. It was noticed that the graph development index should depend on the relative number of edges in relation to the number of nodes and the number of graph cycles, which express the degree of complexity of a settlement unit. Three main groups of villages, characterised by different scales of morphological transformations, were distinguished as a result of the study. Settlement units with orthomorphic transformations, where all spatial modifications were mainly additive and the initial layouts have been preserved almost completely, represent the first group of villages. The second group is composed of units with semi-metamorphic transformations, where the spatial reorganization was significant, but not total. The third group includes villages with metamorphic changes, where the initial layouts have been totallytransformed.


Various direct human impacts changed the hydro-morphology of the Danube during the last centuries. The aims of the present study are (1) to analyze the water regime of the Danube River using the data of Mohács gauging station (1900-2013), and (2) to study the channel development (1952-2014) in connection with water regime changes and human impacts at a section near Bogyiszló (upstream of Mohács). According to the results the height of low water stages decreased by approx. 136 cm (1.2 cm/year), and new, high record flood stages were measured too. The discharge values appertaining to the same low water stages doubled, thus nowadays almost twice as much water flows through the cross-section of the channel at a given stage as at the beginning of the studied period. As the duration of low stages increased, the sandbar development intensified, thus the channel became narrower (by 48% at some places) and deeper thalweg evolved. Therefore, a smaller cross-section for flood-waves evolved, affecting the height of flood. These changes affect shipping, as due to riverbed incision and decrease of low water stages, the lowest shipping water level has to be set repeatedly at lower stages. Besides water extraction from the channel will have difficulties, thus irrigation and industrial cooling water supply will be limited in the future.

Introduction The subject of the research covers the problem of incorporation and morphological changes in former villages on the example of Łódź within its current administrative borders. Studies on the transformation of spatial structures of rural settlements are needed from many points of view. Regional research and comparative analyses on this issue provide better opportunities for introducing more efficient ways of urban planning. At the same time, the identification of changes in rural settlement patterns, taking into account their directions and strength of

DM. The present study was designed to investigate sperm quality and morphological changes in seminiferous tubules and their stage of development in a rat model of type 1 DM induced by STZ [ 14 , 15 ]. Materials and methods We studied 15 male Sprague Dawley rats from the age of 8 weeks, weighing 250–320 g, in compliance with The Animals for Scientific Purposes Act, BE 2558 (AD 2015) (Thai Government Gazette, Vol. 132, Part 18 a, 13th March 2015) under license after approval by the Center for Animal Research Naresuan University, Phitsanulok, Thailand (approval No

, no. 6, pp. 74-77, 2009. 11. Ma Yanli.: Study on the Morphological Changes of Coastline in the Northern Gulf of Guangxi Based on Multi Temporal Image Landsat Remote Sensing, [M]. Guilin, Guilin University of Technology, 2011. 12. Sun Yonggen, high Junguo et al.: Influence of Qinzhou Bonded Port Reclamation Project on Marine Environment, Marine science, Vol. 36, no. 12, pp. 84-89, 2012. 13. Dong Dexin, Li Yichun et al.: Influence of large-scale reclamation on the hydrodynamic environment of the Guangxi Bay, Qinzhou science, Vol. 21, no. 4, 2014.