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Effect of macromolecular mass transport in microgravity protein crystallization

quality. Therefore, the microgravity environment appears to be ideally suited for growing crystals with improved quality ( Kuranova et al., 2011 ; McPherson et al., 1999 ; Snell et al., 1997 ). In this context, it is important to investigate the effect of crystal growth rates versus crystal quality and size. The first reported protein crystallization experiments in microgravity, performed in 1984, described the growth of lysozyme and b-galactosidase crystals on Spacelab-1 ( Littke and John, 1984 ). Since then in subsequent space shuttle missions, unmanned satellite

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The use of microgravity technique in archaeology: A case study from the St. Nicolas Church in Pukanec, Slovakia

References Bishop I., Styles P., Emsley S. J., Ferguson N. S., 1997: The detection of cavities using the microgravity technique: case histories from mining and karstic environments. Modern Geophysics in Engineering Geology, Geological Society, Engineering Geology Special Publication , 12, 153-166. Blížkovský M., 1979: Processing and applications in microgravity surveys. Geophysical Prospecting , 27, 4, 848-861. Butler D. K., 1984: Microgravimetric and gravity gradient techniques

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Salivary and Serum 8-Hydroxydeoxyguanosine Level in Simulated Microgravity

Salivary and Serum 8-Hydroxydeoxyguanosine Level in Simulated Microgravity

Background. Microgravity is associated with an increased of peroxidative. The effect is more pronounced after long duration space flight and can even last for several weeks after landing.

Aim. To determine the influence of a simulated microgravity on antioxidant status of the human body.

Material and Methods. 10 healthy volunteers were studied in condition before, during, and just after the simulated microgravity of -6 head -down -tilt (HDT) bed rest for 10 days. We measured the salivary and serum 8-hydroxydeoxyguanosine before, during and recovery of HDT.

Results. The 8-hydroxydeoxyguanosine showed significant increase in simulating microgravity.

Conclusion. The data provides evidence that oxidative stress is among critical nutritional concerns for long duration space travellers.

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Challenges of ERAU’s First Suborbital Flight Aboard Blue Origin’s New Shepard M7 for the Cell Research Experiment In Microgravity (CRExIM)

Introduction In early 2016, the Department of Applied Aviation Sciences (AAS) at the Embry-Riddle Aeronautical University (ERAU) was granted a suborbital flight opportunity to work on a Science, Technology, Engineering, and Mathematics (STEM) research project. The Spaceflight Operations team in the AAS department was already developing other suborbital payloads as part of the Arete STEM Project (ARETE) to demonstrate joint commercial spaceflight activities. The main aim of this research was to investigate the effect of microgravity on T-cells and to

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Validation of sensitivity and reliability of GPR and microgravity detection of underground cavities in complex urban settings: Test case of a cellar

). Negri S., Margiotta S., Maria Quarta T. A., Castiello G., Fedi M., Florio G., 2015: Integrated analysis of geological and geophysical data for the detection of underground man-made caves in an area in southern Italy. Journal of Cave and Karst Studies. 77 , 52–62. Pánisová J., Pašteka R., Papčo J., Fraštia M., 2012: The calculation of building corrections in microgravity surveys using close range photogrammetry. Near Surface Geophysics, 10 , 391–399. Pašteka R., Richter P., Karcol R., Brazda K., Hajach M., 2009: Regularized derivatives of potential fields

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Peculiarity of Ultrastructure and 45Ca Methabolism of Osteoclasts in Conditions of Hind Limb Unloading and Microgravity

-269. Oganov V. S. bone system weightlessness and osteoporosis. — Moscow: Slovo, 2003. — 260 p. — Russian. Rodionova N. V. The ultrastructural characteristic of osteoclasts in different functional states // Cytology. — 1983. — 25 , N 6. — P. 665-669. — Russian. Rodionova N. V. Functional morphology of the cells in osteogenesis. — Kyiv: Naukova dumka, 1989. — 186 p. — Russian. Rodionova N. V. Cytological mechanisms of bone restructuring at anloading model and microgravity. — Kyiv: Naukova dumka

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Culture cells in a model of microgravity

References 1. Teacher’s Guide to Plant Experiments in Microgravity. United Nations. 2013; 45p. Available at http://www.unoosa.org/pdf/sap/hsti/ZGIP/Teachers_Guide_Plant_L.pdf. 2. Khotianovich M, Stukach Yu, Navasiolava N, Custaud M.A, Kulchitsky V. Glial cells and fibroblasts cooperation and viability in simulated microgravity in vitro. Activitas Nervosa Superior Rediviva 2015; 57(1-2):16-21.

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Space botany in Lithuania. I. Root gravisensing system formation during satellite “Bion-10” flight

References Baldwin K.L., Strohm A.K., Masson P.H., 2013: Gravity sensing and signal transduction in vascular plant primary root. - American Journal of Botany, 100: 126-142. Cowles J.R., Scheld H.W., Lemay R., Peterson C., 1984: Growth and lignification in seedlings exposed to eight days of microgravity. - Annuals of Botany, 54(suppl. 3): 33-48. Driss-Ecole D., Legue V., Carnero-Diaz E., Perbal G., 2008: Gravisensitivity and automorphogenesis of lentil seedling roots grown on board the International Space

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Space botany in Lithuania. II. Study on root gravity sensing during satellite “Bion- 11” flight / Kosminė botanika Lietuvoje. II. Šaknų gravitacijos jutimo tyrimas palydovo „Bion-11“ skrydžio metu

References Baldwin K.L., Strohm A .K., Masson P.H., 2013: Gravity sensing and signal transduction in vascular plant primary root. - American Journal of Botany, 100: 126-142. Driss-Ecole D., Jeune B., Prouteau M., Julianus P., Perbal G ., 2000: Lentil root statoliths reach a stable state in microgravity. - Planta, 211: 396-405. Driss-Ecole D., Legue V ., C arnero-Diaz E., Perbal G ., 2008: Gravisensitivity and automorphogenesis of lentil seedling roots grown on board the International Space Station. - Physiologia

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Investigation of Murine T-Cells and Cancer Cells under Thermal Stressors and 2D Slow Rotating System Effects as a Testbed for Suborbital Flights

Introduction There is a large body of research ( Licato and Grimm, 1999 ; Uva et al., 2002 ; Gridley et al., 2009 ; Singh et al., 2010 ; Thiel et al., 2012 ; Hauschild et al., 2014 ; Martinez et al., 2015 ; Nickerson et al., 2016 ) showing that exposure to microgravity leads to suppressed immunity in both rodents and humans. The downregulation of the immune system is measured by a decreased number of T-cells, alterations in immune cell subsets, epigenetic regulation, slower proliferation rate, and other immunological parameters. Altered gravity has

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