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and management of gynecomastia: defining the role of ultrasound-assisted liposuction. Plast Reconstr Surg 2003; 111(2): 909-23; discussion 924-5. 6. Morselli PG. „Pull-through“: a new technique for breast reduction in gynecomastia. Plast Reconstr Surg 1996; 97(2): 450-4. 7. Bretteville-Jensen G. Surgical treatment of gynaecomastia. Br J Plast Surg 1975; 28(3): 177-80. 8. Simon BE, Hoffman S, Kahn S. Classification and surgical correction of gynecomastia. Plast Reconstr Surg 1973; 51(1): 48-52. 9. Reyes RJ, Zicchi S, Hamed H, et al. Surgical correction of

, Foster SJ, Halvorsen YD, Hicok K, du Laney T et al. Yield of human adipose-derived adult stem cells from liposuction aspirates. Cytotherapy. 2004;6:7. 29. Zhu Y, Liu T, Song K, Fan X, Ma X, Cui Z. Adipose-derived stem cell: a better stem cell than BMSC. Cell Biochem Funct 2008;26:664. 30. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999;284:143. 31. Katsha AM, Ohkouchi S, Xin H, Kanehira M, Sun R, Nukiwa T et al. Paracrine factors of multipotent stromal cells ameliorate

References Alam, M., & Kaminer, M.S. (2010). Liposuction. In B.E. Katz, & N.S. Sadick (Eds.), Body Contouring. Procedures in Cosmetic Dermatology (pp. 69-96). London: Saunders Elsevier. Alsharif, M.J., Labonte, R., & Lu, Z. (2010). Patients beyond borders: a study of medical tourists in four countries. Global Social Policy, 10(3), 315-335. DOI: 10.1177/1468018110380003. Andrei, C.L., Ţigu, G., Drăgoescu, R.M., & Sinescu, C.J. (2014). Analysis of Medical Tourism for Cardiovascular Diseases. Amfiteatru Economic, 16(8), 1136-1150. Bandachowicz, D. (2013

isolation and culture 1st ed. Surabaya: Airlangga Univ. Press; 2009. 7. Baptista L, Silva K, Pedrosa C, Borojevic R. Processing of lipoaspirate samples for optimal mesenchymal stem cells isolation. In: Serdev Nikolay, editor. Advanced techniques in liposuction and fat transfer. Rijeka: Intech; 2011. 8. Fraser JK, Hedrick MH. Systems and methods for treating patients with processed lipoaspirate cells. US Patent no. US 7,501,115 B2 (10 March 2001). [Cited 2012 Jul 8]. Available from: <http://www.freepatentsonline.com/7501115.html> 9. Condé-Green A, de Amorim NF, Pitanguy I

Abstract

Madelung’s disease also called benign symmetric lipomatosis is a rare disorder of unknown etiology. The disease affects almost exclusively middle-aged men with a history of multi-year alcohol abuse. The major symptom is presence of non-encapsulated benign fat masses, especially in the area of the head and neck. Limited head and neck movement, dysphagia, and dyspnea may appear as well.

The diagnosis is clinical and is supported by imaging methods, often elevated hepatic enzymes in blood serum, and histological examination with finding of mature adipose tissue without signs of proliferation. Therapeutic methods involve liposuction or excision which is a method of choice nowadays.

In this article the authors review current knowledge, research state, and present five cases of the Madelung’s disease occurring within the last 10 years at the Clinic of Otorhinolaryngology and Head and Neck Surgery in Martin, Slovakia.

that a dermatologist should be using a scalpel or a liposuction cannula - it comes with the territory and the bell cannot be unrung. It is indisputable that dermatologists are best suited to treat skin disorders: inflammatory, cancerous or esthetic. Unfortunately, specialty training programs in Serbia and some neighboring countries are obviously short of courses improving knowledge and skills. Ever more competitive environment in the field of medicine forces us to move on. In a way this is an appeal to all those who are in a position to have an impact on

. Arch. Orthop. Trauma Surg., 127 (4), 241-244. Morris, D. L. J., Randhawa, N., Rowlands, T. E. (2012). Finding the bigger picture in preoperative assessment. A patient’s story. J. One Day Surg., 23 (1), 23-24. Robles-Cervantes, J. A., Martínez-Molina, R., Cárdenas-Camarena, L. (2005). Heating infiltration solutions used in tumescent liposuction: Minimizing surgical risk. Plast Reconstr Surg., 116 (4), 1077-1081. Shirakami, G., Teratani, Y., Fukuda, K. (2006). Nocturnal episodic hypoxemia after ambulatory breast cancer surgery: Comparison of sevoflurane and propofol

. Surgical induction of zoster in a contralateral homologous dermatomal distribution. Arch Neurol, 2003, 60 (4): 616-617. 52 Andrews TR, Perdikis G, Shack RB. Herpes zoster as a rare complication of liposuction. Plast Reconstr Surg, 2004, 113 (6): 1838-1840. 53 Thomas SL, Wheeler JG, Hall AJ. Case-control study of the effect of mechanical trauma on the risk of herpes zoster. BMJ, 2004, 328 (7437): 439. 54 Schmader K, Studenski S, Macmillan J, et al . Are stressful Life events risk factors for herpes zoster?. J Am Geriatr Soc, 1990, 38 (11): 1188-1194. 55 Cho JW, Shin DH

of the highest quality cells and enable efficient and safe cell culture. Origin and isolation of stem cells The increasing popularity of stem cells in medicine requires an improvement in cell culture methods and techniques of isolation. Adipose-derived stem cells Human adipose-derived stem cells (ASCs) are one of the most frequently used stem cells. ASCs have many applications because they can differentiate towards osteogenic, chondrogenic and adipogenic phenotypes [ 2 ]. The ASCs are collected via surgical excision of the adipose tissue or liposuction, which

beenobserved that large amounts of stem cells can be obtained from large quantities of fat tissue extracted both by aspiration and excision [ 3 ]. ADSCs can be obtained by both liposuction and excision of adipose tissue, which is often discarded aftersurgery, with the former method described as the better method of their preparation for storage. In fact, liposuction sample analysis does not show a significant loss of preadipocytes which shows it does not significantly damage the stroma [ 4 ]. Hence, a large number of ADSCs can be harvested from adipose tissue and do not need