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Well-Differentiated Liposarcoma of The Larynx: A Case Report and Review of Literature

: IARC Press; 2005. 4. Sanz Gonzalo JJ, P. Martinez Molina P, Ribalta Farres MT, Sabater Matadelabarata F. Liposarcoma of the hypopharynx. Acta Otorrinolaryngol Esp. 2002;53( 1): 60-3. 5. Almela Cortis R, Moreno Carazo A, Martin Rodriguez L. Laryngeal and hypopharyngeal liposarcoma. Report of a case and literature review. An Otorrinolaringol Ibero Am. 2002;29(5):431-8. 6. Perez Gonzalez R, Martin Sigüenza G, Alonso Orcajo N, Casas Rubio C. Sarcoma of the larynx. Report of two cases. An Otorrinolaringol Ibero Am. 2003

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Basaloid squamous cell carcinoma of the larynx: case report

References 1. Wain, S.L., Kier, R. & Vollmer, R.T. et al. (1986). Basaloid squamous carcinoma of the tongue hypopharynx and Larynx: report of 10 cases. Hum Pathol. 17, 1158-1166 2. Shanmugartnam, K. & Sobin, L.H. (1991). Histological typing of tumors of the upper respiratory tract and ear. 2nd Edition. Berlin: Springer 3. Vasudev, P., Boutross-Tadross, O. & Radhi, J. (2009). Basaloid squamous cell carcinoma: two case reports. Cases Journal. 2, 9351. DOI: 10.1186/1757-1626-2-9351 4. Wenig, M

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Poor outcome of comprehensive therapy in a case of laryngeal synovial sarcoma

References 1. Lisle JW, Eary JF, O’Sullivan J, Conrad EU. Risk assessment based on FDGPET imaging in patients with synovial sarcoma. Clin Orthop Relat Res 2009; 467: 1605-11. 2. Al-Nemer A, El-Shawarby MA. Laryngeal synovial sarcoma: Case report and literature review. Gulf J Oncolog 2011; 1: 52-6. 3. Miller LH, Santaella-Latimer L, Miller T. Synovial sarcoma of the larynx. Trans Sect Otolaryngol Am Acad Ophthalmol Otolaryngol 1975; 80: 448-451. 4. Fernández-Aceñero MJ, Larach

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Clinical application of laryngeal electromyography – a point of view

., Stollberger R., Schumacher R., Gugatschka M., Friedrich G., Wolfensberger M. - Laryngeal electromyography: electrode guidance based on 3-dimensional magnetic resonance tomography images of the larynx. J Voice, 2012;26(1):110–116, 11. Sittel C., Stennert E., Thumfart W.F., Dapunt U., Eckel H.E. - Prognostic value of laryngeal electromyography in vocal fold paralysis. Arch Otolaryngol Head Neck Surg., 2001;127(2):155-160. 12. Kimaid P.A., Crespo A.N., Quagliato E.M., Wolf A., Viana M.A., Resende L.A. - Laryngeal electromyography: contribution to vocal fold

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Comparison of three and four-field radiotherapy technique and the effect of laryngeal shield on vocal and spinal cord radiation dose in radiotherapy of non-laryngeal head and neck tumors

-guided radiotherapy for laryngeal sparing in head and neck cancer. Oral Oncol. 2010;46(4):283-286. [15] Hamdan A, Geara F, Rameh C, et al. Vocal changes following radiotherapy to the head and neck for non-laryngeal tumors. Eur Arch Otorhinolaryngol. 2009;266(9):1435-1439. [16] Rancati T, Schwarz M, Allen AM. Radiation dose-volume effects in larynx and pharynx. Int J Radiat Oncol Biol Phys. 2010;76(3Suppl):S64-S69. [17] Paulino AC, Arceci RJ. Nasopharyngeal Cancer Treatment & Management. https://emedicine.medscape.com/article/988165-treatment . 2015. [18

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Primary neuroendocrine small cell carcinoma in larynx: case report and literature review

References 1. Barnes L., Eveson J. - WHO Classification of Tumors Pathology and Genetics Head and Neck tumors. IARCPress, Lyon, 2017;p.95-98. 2. Pytal M., Olejniczak I., Kupnicki P., Trenda-Lewy I., Michalecki L. - The small cell carcinoma neuroendocrine type of the larynx - Case Report. Polish Annals of Medicine, 2016;24(1):60-63. 3. Mikic A., Zvrko E., Trivic A., Stefanovic D., Golubovic M. - Small cell neuroendocrine tumor of the larynx - a small case series. Coll Antropol., 2012;36 Suppl 2

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Risk Factors for Laryngeal Cancer in Montenegro

, Vlajinac HD Case-control study of risk factors in laryngeal cancer. Neoplasma 1994;41:43-7. Sokic SI, Adanja BJ, Marinkovic JP, Vlajinac HD Risk factors for laryngeal cancer. Eur J Epidemiol 1995;11:431-3. Gustavsson P, Jakobsson R, Johansson H, Lewin F, Norell S, Rutkvist LE Occupational exposures and squamous cell carcinoma of the oral cavity, pharynx, larynx, and oesophagus: a case-control study in Sweden. Occup Environ Med 1998;55:393-400. Berrino F, Richiardi L, Boffetta P, Esteve J

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A Case Report of Female Patient with Laryngeal Granuloma

ABBREVIATIONS LG - Laryngeal granuloma REFERENCES 1. Jackson C. Contact ulcer of the larynx. Ann Otol Rhinol Laryngol 1928;90: 48-52. 2. Wang CP, Ko JY, Wang YH, Hu YL, Hsiao TY: Vocal process granuloma - A result of long-term observation in 53 patients. Oral Oncol.2009;45(9):821-5. http://www.oraloncology.com/article/S1368-8375%2809%2900026-8/abstract 3. Pickhard A, Reiter R. Benign vocal fold lesions. Laryngorhinootologie. 2013; 92(5):304-12. doi: 10.1055/s-0032-1331162. Epub 2013 Jan 24. http://www.ncbi.nlm.nih.gov/pubmed/23348959

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Original Article. Prevalence of HPV16 IgG Antibody and Rt-Pcr DNAdetection in Patients with Laryngeal Carcinoma and Cervical Dysplasia

Summary

Human papillomaviruses (HPVs) are associated with the most common sexually transmitted infections. It is well documented that high-risk (HR)-HPVtypes are etiologically associated with some cancers. The aim of the study was to investigate HPV16-DNApositivity and prevalence of Ig Gantibody against HPV16 in patients with laryngeal carcinoma and precancerous lesions of cervix uteri in Pleven region, Bulgaria. Material/Methods: We performedacross-sectional study and investigated clinical materials. Attached is real-time PCR-analysis for detection of HPV16-DNA. HPVspecific antibody response by enzyme-linked immunosorbent assay (ELISA) test for detection and quantification of specific Ig Gantibodies in serum were used. Results: For the six-month period, 30 samples were collected and tested. Fourteen of them were found in patients with carcinoma of the larynx and sixteen - in patients with various lesions of cervix uteri.We found that six patients (42.8%) in the first group and eight patients (50%) in the second group were HPV16-DNA-positive. Different age groups were affected. The sera analyzed in this study showed that seven patients (50%) with carcinoma of the larynx were seropositive of whom four (57%) were males. Fourteen of the females with dysplasia (88%) were seropositive. Matching DNApositivity and antibody response were found in 29%of the patients with laryngeal cancer. The match was found in 50%of the females with cervical dysplasia. Conclusions: Real-time PCRisarapid, cost-effective method for detection of HPVs.Ahigh level of seropositivity was found in the two groups of patients.

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Angioedema, a life-threatening adverse reaction to ACE-inhibitors

Abstract

Angioedema with life-threatening site is one of the most impressive and serious reasons for presenting to the ENT doctor. Among different causes (tumors, local infections, allergy reactions), an important cause is the side-effect of the angiotensin converting enzyme (ACE) inhibitors drugs. ACE-inhibitors-induced angioedema is described to be the most frequent form of bradykinin-mediated angioedema presented in emergency and also one of the most encountered drug-induced angioedema. The edema can involve one or more areas of the head and neck region, the most affected being the face, the lips, the tongue, followed by the larynx, when it may determine respiratory distress and even death.

There are no specific diagnosis tests available and the positive diagnosis of ACE-inhibitors-induced angioedema is an exclusion diagnosis. The authors performed a review of the most important characteristics of the angioedema caused by ACE-inhibitors and present their experience emphasizing the diagnostic algorithm.

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