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Identification of differentially expressed genes associated with the enhancement of X-ray susceptibility by RITA in a hypopharyngeal squamous cell carcinoma cell line (FaDu)

Introduction Head and neck squamous cell carcinoma (HNSCC), which arises in the head and neck region that composes pharynx, larynx, nasal cavity, oral cavity, paranasal sinuses and salivary glands, has an estimated 500,000 new cases and becomes the sixth most common cancer in 2010 worldwide. 1 As one type of HNSCC, hypopharyngeal squamous cell carcinoma (HSCC) has a poor prognosis, and the overall survival rate for HSCC patients is only 15–45%. 2 , 3 The patients diagnosed with HSCC are often at a late stage and distant metastasis occur after

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Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) may be superior to C-reactive protein (CRP) for predicting the occurrence of differentiated thyroid cancer

H, Gao L, Liu X, Ma L, Lu M, Gao Z. Preoperative neutrophil-to-lymphocyte ratio as prognostic predictor for hypopharyngeal squamous cell carcinoma after radical resections. J Craniofac Surg 26, e137–e140, 2015. Szkandera J, Gerger A, Liegl-Atzwanger B, Stotz M, Samonigg H, Friesenbichler J, Stojakovic T, Leithner A, Pichler M. The derived neutrophil/lymphocyte ratio predicts poor clinical outcome in soft tissue sarcoma patients. Am J Surg 210, 111–116, 2015. Turkmen K, Erdur FM, Ozcicek F, Ozcicek A, Akbas EM, Ozbicer A, Demirtas L, Turk S, Tonbul HZ

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Prognostic role of diffusion weighted and dynamic contrast-enhanced MRI in loco-regionally advanced head and neck cancer treated with concomitant chemoradiotherapy

: before treatment; bottom: after 10 Gray of chemo-radiotherapy. Figure 2 65 year old patient with hypopharyngeal squamous cell carcinoma (T2 N2) who died 14 months of starting of chemo-radiotherapy due to disease relaps into the lungs. Axial post-contrast T1 images, co-registred and corresponding apparent diffusion coefficient (ADC) maps and color-coded dynamic contrast-enhanced MRI derived volume transfer constant (Ktrans), extracellular extravascular fraction (Ve) and plasma volume fraction (Vp) maps in the area of the tumour (arrows) are shown. Top: before

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