Jinwei Luan, Xianglan Li, Rutao Guo, Shanshan Liu, Hongyu Luo and Qingshan You
Head and neck squamous cell carcinoma (HNSCC), which arises in the head and neck region that composes pharynx, larynx, nasal cavity, oral cavity, paranasal sinuses and salivary glands, has an estimated 500,000 new cases and becomes the sixth most common cancer in 2010 worldwide. 1 As one type of HNSCC, hypopharyngealsquamouscellcarcinoma (HSCC) has a poor prognosis, and the overall survival rate for HSCC patients is only 15–45%. 2 , 3 The patients diagnosed with HSCC are often at a late stage and distant metastasis occur after
S Ozmen, O Timur, I Calik, K Altinkaynak, E Simsek, H Gozcu, A Arslan and A Carlioglu
H, Gao L, Liu X, Ma L, Lu M, Gao Z. Preoperative neutrophil-to-lymphocyte ratio as prognostic predictor for hypopharyngealsquamouscellcarcinoma after radical resections. J Craniofac Surg 26, e137–e140, 2015.
Szkandera J, Gerger A, Liegl-Atzwanger B, Stotz M, Samonigg H, Friesenbichler J, Stojakovic T, Leithner A, Pichler M. The derived neutrophil/lymphocyte ratio predicts poor clinical outcome in soft tissue sarcoma patients. Am J Surg 210, 111–116, 2015.
Turkmen K, Erdur FM, Ozcicek F, Ozcicek A, Akbas EM, Ozbicer A, Demirtas L, Turk S, Tonbul HZ
Manca Garbajs, Primoz Strojan and Katarina Surlan-Popovic
: before treatment; bottom: after 10 Gray of chemo-radiotherapy.
65 year old patient with hypopharyngealsquamouscellcarcinoma (T2 N2) who died 14 months of starting of chemo-radiotherapy due to disease relaps into the lungs. Axial post-contrast T1 images, co-registred and corresponding apparent diffusion coefficient (ADC) maps and color-coded dynamic contrast-enhanced MRI derived volume transfer constant (Ktrans), extracellular extravascular fraction (Ve) and plasma volume fraction (Vp) maps in the area of the tumour (arrows) are shown. Top: before