Search Results

1 - 2 of 2 items :

  • "hydroxyphenylethanone" x
Clear All

Abstract

Within the framework of the study of the synthesis and high-performance liquid chromatography (HPLC) enantioseparation the series of 9 derivatives of 3-hydroxyphenylethanone was prepared by a well-tried method. The structure of the prepared compounds was confirmed on the basis of interpretation of the IR, UV, 1H NMR and 13C NMR spectra. An enantioseparation of prepared compounds was performed using HPLC on a native teicoplanin (Chirobiotic T) and the amylose tris (3,5-dimethylphenylcarbamate) (Chiralpak AD) chiral stationary phases, which is more suitable for the enantioseparation of all prepared compounds especially with heterocycles in the basic part of a molecule.

-hydroxypropiophenone derivatives-potential blockers of beta-adrenoceptors (in Slovak). Čes Slov Farm. 1994a;3:226-228. [9] Čižmarikova R, Kozlovsky J. Pharmacological evaluation of 4-hydroxypropiophenone-potential beta-adrenoreceptor blockers (in Slovak). Farm Obzor. 1994b;63:258-260. [10] Čižmarikova R, Račanska E. Beta-adrenergic receptor blockers II. Aryloxyaminopropanols. (Review in Slovak).Farm Obzor. 1998;67:113-117. [11] Čižmarikova R, Polakovičova M, Mišikova E. Synthesis, physicochemical properties and conformational studies of (3-chloromethyl-4-hydroxyphenyl)ethanones