Anna Malm, Anna Glowniak-Lipa, Izabela Korona-Glowniak and Tomasz Baj
Recently, several studies have been undertaken so as to develop more effective therapeutic approaches towards eradicating Helicobacter pylori. Among these is phytotherapy. The aim of this study was to investigate the activity in vitro of the plant extracts obtained from common herbs cultivated in the Lubelszczyzna region against the reference strain H. pylori ATCC 43504. Among these are thyme herbs, chamomile flowers, peppermint leaves and coneflower herbs. Herein, it was found that the MIC values of the assayed extracts were as follows: the extracts from coneflower herbs showed anti-H. pylori activity with MIC = 31.3-125 μg/ml; the extracts from chamomile flowers demonstrated MIC = 31.3-62.5 μg/ ml; the extracts from peppermint leaves had MIC = 15.6-250 μg/ml; and the extracts from thyme herbs revealed MIC = 15.6-62.5 μg/ml, depending on the solvent used. The most active were the extracts obtained with ethyl acetate or ethanol alcohol absolute 99.8%. These showing MIC within the range of 15.6-62.5 μg/ml, while the lowest activity was observed in case of the extract obtained with 70% aqueous ethanol. This last showing MIC within the range of 62.5-250 μg/ml. The MIC values of essential oil components were 15.6 μg/ml for bisabolol and menthol or 31.3 μg/ml for thymol. The obtained data indicate that the assayed herbs possessed promising anti-H. pylori bioactivity.
The paper describes basic determinants of the medical plant cultivation in Polish agriculture. The author discussed economic background of the introduction of these plants indicating the role of pharmaceutical industry in herb usage. Then, there is a presentation of results of the survey study carried out among farmers from the Wielkopolska region. Approximately 10% of the farms cultivate medicinal plants but more than 50% declare some interest in this kind of production, what indicates a big potential. Farmers think that herbs are economically attractive crops if the sale is guaranteed and the price is satisfactory. The demand for medicinal plants is developing and expanding for e.g. dietary supplements and other health-promoting products. Therefore, it can be concluded that cultivation of medicinal plants is the prospective direction of agricultural production and an important element of additional income of Polish farmers.
Biljana Kaličanin, Dragan Velimirović, Ivana Arsić and Sofija Đorđević
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