Witold Kozirok, Ewa Babicz-Zielińska and Bartłomiej Krzebietke
6. Krejpcio Z., Skwarek K., Hyżyk A.K., Dyba S. (2011). Evaluation of prevalence of dietarysupplements intake in a selected group of sports people. Problemy Higieny i Epidemiologii 92(4), 935-938. [in Polish]
7. Charzewska J., Wajszczyk B. (2011). Nutritional supplements vs. intense physical exercise. In M. Jarosz (Ed.), Nutritional supplements vs. health (pp. 106-119). Warszawa: Wydawnictwo Lekarskie PZWL. [in Polish]
8. Celejowa I. (2011). Physical activity vs
Agnieszka Marzec, Michał Skrzypek and Zbigniew Marzec
konsumenta. Żywność. Nauka. Technologia. Jakość. 2011;4(77):5-23.
22. Nachtigal MC, Patterson RE, Stratton KL, et al. Dietarysupplements and weight control in a middle-age population. J Altern Complement Med. 2005;11(5):909-15.
23. Yazaki Y, Faridi Z, Ma Y, et al. A pilot study of chromium picolinate for weight loss. J Altern Complement Med. 2010;16(3):291-9.
24. Rozporządzenie Ministra Zdrowia z dnia 24 kwietnia 2017 r. zmieniające rozporządzenie w sprawie składu oraz oznakowania suplementów diety (Dz. U z 18 maja 2017r
Introduction. The interest in weight loss supplements can be noticed in Poland at the moment. It is related to people’s trying to look good as fast as possible. The pharmaceutical market puts an emphasis only on the benefits and majority of the people purchasing the supplements do not regard doctor’s advice as necessary. Therefore, in order to learn about consumers’ awareness about the use of dietary supplements is gaining importance.
Aim. The objective of the study was to gain knowledge about choice preferences of dietary supplements used in weight loss, like also to learn about consumer’s awareness about the use of dietary supplements.
Material and methods. An anonymous survey was conducted in Mielec in 2015 among 112 women. The questionnaire included questions concerning their knowledge of dietary supplements, the type and amount of consumption, the reasons for using supplements, benefits and health risks of their use.
Results. 90.2% of women admitted that they are using or they used dietary supplements in order to reduce weight. Respondents most often derive the information about these preparations from the pharmacist (62.5%), television (46.4%), a doctor (36.6%), radio (30.4%), the Internet (29.5%). 72.4% of female respondents pay attention to the composition of dietary supplement, with the emphasis on the amount of the ingredients (64.3%), its dosage (55.4%), the origin of the ingredients (natural or synthetic) (37.5%). Female respondents prefer dietary supplements either in the form of tablets (83.9%) and capsules (54.7%), as well as in liquid (52.7%).
Conclusions. Respondents showed an increased interest in supplements used for weight loss and they usually use it in forms of tablets and capsules. As the role of the Internet increases, it is necessary to educate consumers about ability to search reliable sources of information about dietary supplements used for weight loss.
Amalia Miklos, Amelia Tero-Vescan, Lénárd Farczádi and Daniela-Lucia Muntean
Objective: The purpose of this study was to develop a low-cost, yet sensitive and precise UHPLC method for the quantitative determination of ostarine from dietary supplements (DS) for athletes. The analytical performance of the method was verified on a DS legally acquired from a specialized website for athletes. The uniformity of mass and content of the ostarine DS was also verified.
Methods: For the quantitative determination of ostarine a UHPLC method was developed and validated. The separation was performed using a reversed-phase C18 column, using a mixture of 75% methanol: 25% formic acid 0.1% in isocratic elution, at a flow rate of 0.5 ml/min. The uniformity of mass and content of DS was performed following the methodology described in the European Pharmacopoeia 7th Edition.
Results: The validated method was specific and linear on the concentration range of 1-25 µg/ml and was precise and accurate at all concentration levels, according to the official guidelines for validating analytical methods. An average mass of 510 mg content was obtained for the ostarine capsules, with an RSD of 2.41%. Regarding the uniformity of the content, an average of 4.65 mg ostarine/capsule was obtained with an RSD of 1.05%.
Conclusions: The developed UHPLC method was suitable, rapid, sensitive and allowed quantitative determination of active substance content in a DS with ostarine (92.91% ostarine/capsule from 5 mg ostarine/capsule declared by the manufacturer).
Adrian Głogowski, Zbigniew Marczyński, Michał Krzysztof Kołodziejczyk, Jerzy Jambor, Marta Kinga Stefan and Marian Mikołaj Zgoda
Introduction: Dietary supplements are a good way to supplement the deficiency of certain micronutrients and organic components (therapeutic agents) in human body. They are most often available in concentrated form as tablets, capsules, powder or liquid.
Objective: To investigate morphological parameters and the pharmaceutical availability of coated tablets – dietary supplements – that contain selected pharmacopeial titrated dry plant extracts.
Methods: Testing of the effective time of the tablet surface erosion was performed in model acceptor fluids using pharmacopeial methods in static (Erweka apparatus) and dynamic (unlimited diffusion method) conditions. Furthermore, morphological parameters of tablets (the original shape of an ellipse) as well as their hardness were determined.
Results: The effective erosion time was determined by conductometric method using carboxymethylcellulose sodium salt (NaCMC) contained in the tablet. The content of gum arabic and NaCMC in the tablet testifies that the granulate was produced using the “wet granulation” technique which resulted in high hardness of original, esthetic, elliptical tablets and in prolonged disintegration time (erosion).
Conclusions: The used excipients: gum arabic and NaCMC for the production of the tested tablets containing selected dry plant extracts result in their high hardness. The tested dietary supplements are characterized by esthetic design, original shape, and prolonged disintegration time which affects the pharmaceutical availability.
Anna Łozak, Krystyna Sołtyk, Monika Kiljan, Zbigniew Fijałek and Piotr Ostapczuk
Determination of Selected Trace Elements in Dietary Supplements Containing Plant Materials
The need for analytical methods enabling determining trace metals concentration in herbal medicinal products and dietary supplements has increased in recent years due to the globalisation of international market and also due to the risk of using herbs contaminated by heavy metals. To this end, an analytical method was developed and validated for the accurate determination of trace elements (As, Cd, Co, Cr, Cu, Mn, Pb, Sr, Zn) in products in the form of tablets or capsules, herbal teas and their aqueous infusions. The validation of described procedure of digestion samples and determination metals by ICP-MS method, shows its usability in determination of trace elements in herbal products. Recovery percentage based on CRMs ranged from 90.1% to 110.7%, and the precision of the method was below 3%.
Out of all microelements determined, the highest concentration was found for Mn in herbal teas. The daily intake of Mn with infusions accounted for 53.3% and 126.4%, which corresponded to 41.7% and 98.9% of the AI values for adult women and men, respectively. The method was also used for quality control of the labelled level of chromium and zinc. In all analysed samples, the concentrations of cadmium and lead were below the EC maximum levels stipulated for Cd and Pb in dietary supplements.
Edyta Kowalczuk-Vasilev, Renata Klebaniuk, Wioletta Samolińska, Bożena Kiczorowska and Filip Bielak
. Interwencje żywieniowe u niedożywionych dzieci. Stand Med. 2004;3:322-32.
14. Williams MH. Dietarysupplements and sports performance: minerals. J Int Soc Sports Nutr. 2005;2(1):43-9.
15. Knapik JJ, Steelman RA, Hoedebecke SS, et al. Prevalence of dietarysupplement use by athletes: systematic review and meta-analysis. Sports Med. 2016;46(1):103-23.
Michal Kumstát, Tomáš Hlinský, Ivan Struhár and Andy Thomas
Many athletes use dietarysupplements in an effort to maximize performance. It is widely accepted that ingestion of dietarysupplements that may nutritionally affect intracellular and extracellular buffering capacity are an evidence-based strategy for improving sports performance ( Maughan, 2014 ).
Consumption of dietary sodium bicarbonate (SB) prior to exercise induces alkalosis by increasing blood bicarbonate pool and pH. This in turn enhances the buffering capacity of the extracellular space in the working muscle by influencing the efflux of
Justyna Baraniak, Radosław Kujawski and Marcin Ożarowski
Food supplements are concentrated sources of nutrients and/or other substances with a nutritional or physiological effect. However, they often contain herbal substances or their preparations. Food supplements belong to category of food and for that reason are regulated by food legislation. European Union regulations and directives established general directions for dietary supplements, dietetic food, which due to their special composition or manufacturing process are prepared for specific groups of people with special nutritional needs, and novel food/novel food ingredients to ensure product safety, suitability and appropriate consumer information.
Akhavan-Salamat H., Ghasemi H.A. (2015). Alleviation of chronic heat stress in broilers by dietarysupplementation of betaine and turmeric rhizome powder: dynamics of performance, leukocyte profile, humoral immunity, and antioxidant status. Trop. Anim. Health Prod., doi: 10.1007/s11250-015-0941-1.
Al - Fataftah A.R., Abdelqader A. (2014). Effects of dietary Bacillus subtilis on heat-stressed broilers performance, intestinal morphology and microflora composition. Anim. Feed Sci. Technol., 198: 279