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Fusion of clinical data: A case study to predict the type of treatment of bone fractures

). The WEKA data mining software: An update, ACM SIGKDD Explorations Newsletter 11 (1): 10–18. Haq, A. and Wilk, S. (2017). Fusion of clinical data: A case study to predict the type of treatment of bone fractures, in M. Kirikova et al. (Eds.), New Trends in Databases and Information Systems , Springer, Cham, pp. 294–301. Hossain, M., Neelapala, V. and Andrew, J.G. (2008). Results of non-operative treatment following hip fracture compared to surgical intervention, Injury 40 (4): 418–421. Jesneck, J., Nolte, L., Baker, J., Floyd, C. and Lo, J

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Comparison of clinical data based on limits of agreement


Two different medical measurement methods, which usually do not produce exactly the same results, are used to analyse the serum levels of folic acid in a blood sample. We assess the (dis)agreement of the available data in order to replace the old method (the reference method, which involves a lot of human intervention) with the new one (which uses mostly machines), without causing problems in clinical interpretation. The 95% limits of agreement are estimated, before and after a logarithmic transformation, and an appropriate use of regression and a nonparametric approach are also considered. The application of these different statistical techniques is very useful and easily interpreted by medical researchers, but the results obtained do not provide confidence that the new method can be used in place of the old one for clinical purposes.

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Hyperglycaemia Among Nigerian Infants Weighing Less Than 1,500 Grammes at Birth: A Retrospective Assessment of the Clinical Data


Background and Aims: In very low birthweight (VLBW) infants, birthweight < 1,500g, hyperglycaemia is associated with increased rates of mortality and morbidity. Our study aimed at determining the prevalence of hyperglycaemia among VLBW infants and describing their clinical characteristics. Methods: A retrospective chart review of all inborn VLBW infants was performed. Information obtained included birthweight, gestational age (best obstetric record), gender, and history of chorioamnionitis/maternal medical disorders, type and rates of intravenous fluid administration. Blood glucose level ≥ 7 mmol/L on at least two occasions defined hyperglycaemia. Results: Of the 279 blood glucose values, obtained from 93 infants, 91 (32.6%; 95% CI = 27.1% -38.1%) were in the hyperglycaemic range, with the majority (61.5%) occurring in the first 48 hours of life. The frequency of hyperglycaemia was significantly associated with a rate of infusion greater than 0.4g/kg/hour (Odds Ratio, OR = 3.76; 95% CI=1.58-8.94) and a positive history of maternal chorioamnionitis (OR = 3.04; 95%CI= 1.15-8.01). Conclusion: In the first 48 hours of life, hyperglycaemia co-existing with or complicating primary illnesses was common in VLBW infants who had dextrose infusion and a positive history of maternal chorioamnionitis

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Recommendations for improving the quality of reporting clinical electrochemotherapy studies based on qualitative systematic review

how to present data and important elements to include in discussions. Although these guidelines provide a fundamental guidance for conducting a valid clinical trial and reporting generalizable findings, nonetheless it is recognized that there is a need for specialty-specific guidelines and that these guidelines will lead to improvement in the quality of reports and to higher impact publications. 32 , 33 In the field of electrochemotherapy, comprehensive meta-analyses or Cochrane style reviews of efficiency are hampered by the lack of some relevant clinical data in

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Optimization of MSC therapeutic strategies for improved GVHD treatment

estimated 5-year survival rates of 25% and 5%, respectively [ 8 ]. Because of their powerful immunosuppressive ability, mesenchymal stem cells (MSCs) have been used in the treatment of immune diseases. Animal studies have shown that MSCs improve the engraftment of HSCs and ameliorate GVHD [ 9 , 10 , 11 , 12 ], and subsequent clinical data have further confirmed their efficacy in treating refractory GVHD [ 13 , 14 , 15 , 16 , 17 ]. For example, patients receiving co-transplantation of MSCs at the time of cord blood transplantation (CBT) had a significantly faster

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The prevalence of inappropriate blood tests in pediatric patients scheduled for elective surgery in Thailand: a retrospective chart review

patients scheduled for elective surgery at Siriraj Hospital ( Supplementary Table ), and determine the factors that correlated with the prevalence of inappropriate laboratory testing. Materials and methods This study was approved by the Institutional Review Board at Siriraj Hospital (021/2554(EC4)). The medical records of children <15 years old, who were admitted to the surgical ward for elective surgery between May and October 2010, were reviewed retrospectively. We recorded patient demographic and clinical data including age, sex, their physical status class

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The role of endoscopic ultrasound and endoscopic resection for gastric glomus: A case series and literature review

were treated at Shengjing Hospital of China Medical University between March 2011 and March 2017 was retrospectively analyzed. At the same time, we reviewed the EUS characteristics of GISTs, leiomyomas, ectopic pancreas, and schwannomas in patients. The EUS characteristics and patients’ clinical data as well as their treatment were reviewed. The study was approved by the Ethics Committee of China Medical University and all the patients signed written informed consent. Methods Endoscopic ultrasound All EUS procedures were performed with a linear scanning

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Smart and Connected Health: What Can We Learn from Funded Projects?

electronic textiles for ambulatory health monitoring; 4) exploring clinical data and its applications in cohort identification, assessment of acute respiratory distress syndrome and privacy-preserving; 5) conducting education and academic activities of SCH, including international conference, mHealth summer training institute, doctoral consortium, etc. This study is an extension of our previous study (Chen, Chen, Qu, Chen, & Ding, 2018), which only analyzed 100 active SCH projects in 2018. In this study, we applied different automatic analysis approaches such as

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CT findings predict survival of patients with peripheral T cell lymphoma: a preliminary study

, and all of the biopsy specimens were reviewed through immunohistochemical examination. The patient inclusion criteria were as follows: (a) no patient received any treatment; (b) each patient had complete CT data (unenhanced scan and contrast-enhanced scan of head and neck, chest, and abdominopelvic area); (c) visible tumor on CT. Clinical data collected included the patient’s age, gender, tumor location, tumor stage, treatment and outcome. Image analysis CT examinations of 10 patients were performed on a PQ5000 spiral CT scanner (Picker, New York, NY, USA), 41

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Thyroid cancer detection rate and associated risk factors in patients with thyroid nodules classified as Bethesda category III

ratios for the risk of malignancy according to clinical and US features and multivariate logistic regression with a backward stepwise selection method was performed to select independent predictors of malignancy. In all cases p-value < 0.05 was considered statistically significant. Results A total of 112 Bethesda category III nodules from 105 patients were included in this study. The clinical data and US features of all nodules are shown in Table 1 . Among the 112 nodules, 35 (31.2%) had final diagnosis of malignancy and 77 (68.8%) had benign lesions. Of the

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