, Rubens RD. The biology and management of bone metastases. Crit. Rev. Oncol. Hematol. 1999; 31:89–96. 8. Roodman GD. Mechanisms of bonemetastasis. N. Engl. J. Med. 2004; 350:1655–1664. 9. Hage WD, Aboulafia AJ, Aboulafia DM. Incidence, location, and diagnostic evaluation of metastatic bone disease. Orthop. Clin. N. Am. 2000; 31:515–528. 10. Blum R.H., Novetsky D., Shasha D., Fleishman S. The multidisciplinary approach to bone metastases. Oncology. 2003;17:845–857; discussion 862–863, 867. 11. Moriwaki S. Histopathology and statistical analysis of spinal metastases of
cells in metastatic sites. Nature. 2 August 2002; 563-672. 5. Liang H, Wang XN, Wang BG et al. Prognostic factors of young patients with colon cancer after surgery. World J Gastroenterol. 2006; 12:1458-62. 6. Ihle PM, McBeath AA. Bonemetastasis from colonic carcinoma. A case report. J Bone Joint Surg Am. 1973; 55:398-400. 7. Daldrup-Link HE, Franzius C, Link TM et al. Whole-body MR imaging for detection of bone metastases in children and young adults: comparison with skeletal scintigraphy and FDG PET. AJR Am J Roentgenol. 2001; 177:229-36. 8. Delva R, Pein F
examinations had a crucial role both in the diagnostic orientation and in
the subsequent therapeutic decisions and proper monitoring under therapy.
Keywords: renal cell carcinoma, expansile bonemetastasis
osteosynthesis could not compensate the progressive bone loss and the permanent
use of an external orthosis was mandatory. The survival rate was 82,81% at 6 months and 67,19%
at 12 months.
Conclusions. All patients could be mobilized. Two thirds of the patients will survive more than a
year. The goals of osteosynthesis are the same, regardless the location of the fracture and implant
used: pain amelioration, stability for immediate full weight bearing, durability for patient’s life
Keywords: bonemetastasis, intramedullary nail, long bones
The diagnosis of follicular thyroid cancer is based on postoperative histopathology assessment. In its minimally invasive form, the signs of vascular invasion and capsular infiltration may sometimes be seen only in a small tumor fragment; hence, the diagnosis should be based on multiple histopathology specimens. This case study is a report on a 70-year-old female who was diagnosed with spinal metastasis of follicular thyroid cancer. This diagnosis was established 5 years after partial strumectomy due to goiter and there were no signs of thyroid cancer in postoperative histopathology assessment. Based on this case and literature reports, the authors conclude that the diagnosis of follicular thyroid cancer, especially its minimally invasive forms, may pose a diagnostic problem even when based on postoperative histopathology.