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Animal models of maternal depression for monitoring neurodevelopmental changes occurring in dams and offspring

REFERENCES Ashcroft GW, Crawford TB, Eccleston D, Sharman DF, MacDougall EJ, Stanton JB, Binns JK. (1966). 5-hydroxyindole compounds in the cerebrospinal fluid of patients with psychiatric or neurological diseases. Lancet (London, England) 2 : 1049–52. Barros VG, Rodríguez P, Martijena ID, Pérez A, Molina VA, Antonelli MC. (2006). Prenatal stress and early adoption effects on benzodiazepine receptors and anxiogenic behavior in the adult rat brain. Synapse 60 : 609–18. Belzung C, Lemoine M. (2011). Criteria of validity for animal models of

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Advances in Animal Models of Hepatitis B Virus Infection

dependent upon new viral DNA synthesis. Virology, 2010, 406(2): 286-292. 14 Yang Q, Zhao X, Zang L, et al . Anti-hepatitis B virus activities of alpha -DDB -FNC, a novel nucleoside -biphenyldicarboxylate compound in cells and ducks, and its anti-immunological liver injury effect in mice. Antiviral Res, 2012, 96(3): 333-339. 15 Menne S, Cote PJ. The woodchuck as an animal model for pathogenesis and therapy of chronic hepatitis B virus infection. World J Gastroenterol, 2007, 13(1): 104-124. 16 Fletcher SP, Chin DJ, Ji Y, et al . Transcriptomic analysis

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Habituation of exploratory behaviour in VPA rats: animal model of autism

-medicated, fi rst-episode schizophrenia. Biol Psychiatry 54: 121-128. Lynn DA, Brown GR. (2009). The ontogeny of exploratory behavior in male and female adolescent rats (Rattus norvegicus). Dev Psychobiol 51: 513-520. Markram K, Rinaldi T, La Mendola D, Sandi C, Markram H. (2008). Abnormal fear conditioning and amygdala processing in an animal model of autism. Neuropsychopharmacology 33: 901-912. Michael N, Ostermann J, Sörös P, Schwindt W, Pfl eiderer B. (2004). Altered habituation in the auditory cortex in a subgroup of

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Effects of Chronic Psychosocial Stress on Reduction of Basal Glucocorticoid Levels and Suppression of Glucocorticoid Levels Following Dexamethasone Administration in Animal Model of PTSD

following dexamethasone administration in combat veterans with and without posttraumatic stress disorder. Arch Gen Psychiatry. 1995;52, 583-593. 7. Yehuda R, Boisoneau D, Mason JW, Giller EL. Glucocorticoid receptor number and cortisol excretion in mood, anxiety, and psychotic disorders. Biol Psychiatry. 1993;34: 18-25. 8. Zoladz PR, Conrad CD, Fleshner M, Diamond DM. Acute episodes of predator exposure in conjunction with chronic social instability as an animal model of post-traumatic stress disorder.Stress. 2008; 11: 259

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Improvement of Large Animal Model for Studying Osteoporosis

histomorphometric study. Osteoporos Int 1993, 3, 97-102. 4. Chavassieux P, Buffet A., Vergnaud P, Garnero P., Meunier P.J.: Short-term effects of corticosteroids on trabecular bone remodeling in old ewes. Bone 1997, 20, 451-455. 5. Davidson M.K, Lindsey J.R, Davis J.K.: Requirements and selection of an animal model. Jsr J Med Sci 1987, 23, 551-555. 6. Ding M, Cheng L, Bollen P., Schwarz P, Overgaard S.: Glucocorticoid induced osteopenia in cancellous bone of sheep: validation of large animal model for spine fusion and biomaterial research. Spine 2010, 35, 363-370. 7. Fox

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Experimental studies on the treatment of streptococcal infections with hyperbaric oxygenation

Abstract

The article presents the results of research into the therapeutic effect of hyperbaric oxygenation on bacterial infections performed on an animal model. The studies were performed on Porton mice infected intraperitoneally with haemolysing streptococci and later subjected, over a 3-day period, to 5 exposures of hyperbaric oxygenation at a pressure of 2.8 ata. Depending on the research group, the treatment was commenced after 24, 48, 72 and 96 hours from the moment of infection. Some of the animals died during the experiment.8 and 12 days from the date of infection, selected animals of each group were put to death and subjected to post mortem examination. A statistically significant positive effect of hyperbaric treatment on the survival rate, as well as on the development of complications (liver abscesses), was observed in those animals where the hyperbaric oxygenation was applied at an early stage. In groups where the therapy was initiated later, no positive effect was noted, and the complications tended to develop more rapidly.

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Establishment of renal failure models by laparoscopy in bama pigs which underwent partial nephrectomy and radical contralateral nephrectomy

its death. The application of liquid nitrogen and electrocoagulation and the removal of the contralateral kidney did not give a good result either ( 2 ). The miniature pig has unmatched advantages as an animal model because of its high homology with humans. In recent years, the miniature pig has received more and more attention as a comparative medicine animal model ( 5 , 17 ) and has been widely used in many fields of medicine ( 11 , 12 , 16 ). Laparoscopic studies for many surgical procedures have been performed on small animals ( 14 , 15 ). Renal failure

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Current status of in vitro and in vivo antifungal activities of posaconazole

Abstract

Posaconazole (POS) is a new triazole drug with broad-spectrum in vitro activity against most yeasts and molds such as Candida, Cryptococcus neoformans, Aspergillus, Fusarium and Zygomycetes, as well as certain species of dimorphic fungi and endemic fungi. In immunocompetent or immunocompromised animal models with invasive fungal infections, POS has demonstrated highly effective, broad-spectrum antifungal activities. In vitro and in vivo antifungal activities of POS were superior to those of other azoles against Candida glabrata, Candida krusei, Aspergillus terrus, Fusarium and Zygomycetes. In vivo susceptibility studies have shown promising efficacy of POS against life-threatening fungal infections in animal models with different immune status and infection sites.

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Experimental Research Into the Effect of Hyperbaric Exposures

Abstract

Numerous research works indicate that staying in a hyperbaric environment is a stressor. We have undertaken studies using an animal model to determine the effect of hyperbaria on adrenocortical secretion and the level of adrenal ascorbic acid (a.a.a.). The research was conducted on 70 male hooded rats, which were divided into groups and subjected to hyperbaric air and oxygen at an overpressure of 1 and 3 atn, with some of the animals being additionally burdened with physical effort (swimming). It was found that short-term exposures (30 minutes) of rats to hyperbaric conditions caused a decrease in the content of a.a.a. With a prolonged (3-hour) exposure to 3 atm air the a.a.a. content returns to a normal level. A reduction in the a.a.a. content indicates the presence of stress in hyperbaric conditions in the rat, however, it does not allow to determine its intensity with the method used in the study.

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Immuno-histomorphometric and -fluorescent characteristics of GH cells after treatment with genistein or daidzein in an animal model of andropause

:193-199. 13. Picherit C, Coxam V, Benne tau-Pelissero C, Kati-Coulibaly S, Davicco MJ, Lebecque P, Barlet JP: Daidzein is more effi cient than genistein in preventing ovariectomy-induced bone loss in rats. J Nutr 2000, 130:1675-1681. 14. Ajdzanovic VZ, Sosic-Jurje vic BT, Filipovic BR, Trifunovic SL, Milosevic V: Daidzein effects on ACTH cells: immunohistomorphometric and hormonal study in an animal model of the andropause. Histol Histopathol 2011, 26:1257-1264. 15. Ajdzanovic VZ, Sosic-Jurje vic BT, Filipovic BR, Trifunovic SL, Brkic DD

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