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Prognostic value of soluble angiotensin II receptor 1 and soluble angiotensin converting enzyme (CD 143) in patients with acute leukemia

Introduction There is increasing evidence that angiotensin II (Ang II), a major regulator of blood pressure and cardiovascular homeostasis, is involved in the regulation of cell proliferation, angiogenesis, inflammation and tissue remodeling, which suggests that this peptide might also play a role in cancer [ 1 ]. The renin-angiotensin system (RAS) has been characterized extensively in hypertension and atherosclerosis, but recently its relevance to the fields of oncology and hematology are being studied [ 2 , 3 ]. The RAS pathway mediates its effect

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Effect of Dual Blockade of Renin-Angiotensin System on Proteinuria

References 1. Elliott WJ: Therapeutic trials comparing angiotensin converting enzyme inhibitors and angiotensin II receptor blockers. Curr Hypertens Rep. 2000; 2:402-411. 2. Izzo JL Jr, Weir MR. Angiotensin-converting enzyme inhibitors. J Clin Hypertens (Greenwich) 2011; 13:667. 3. Taylor AA, Siragy H, Nesbitt S. Angiotensin receptor blockers: pharmacology, efficacy, and safety. J Clin Hypertens (Greenwich) 2011; 13:677. 4. Hanevold CD. Acute renal failure during lisinopril and losartan

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Alternative renin-angiotensin system pathways in adipose tissue and their role in the pathogenesis of obesity

References Achard V, Boullu-Ciocca S, Desbriere R, Nguyen G, Grino M. Renin receptor expression in human adipose tissue. Am J Physiol Regul Integr Comp Physiol 292, R274–282, 2007. Achard V, Tassistro V, Boullu-Ciocca S, Grino M. Expression and nutritional regulation of the (pro)renin receptor in rat visceral adipose tissue. J Endocrinol Invest 34, 840–846, 2011. Albiston AL, McDowall SG, Matsacos D, Sim P, Clune E, Mustafa T, Lee J, Mendelsohn FA, Simpson RJ, Connolly LM, Chai SY. Evidence that the angiotensin IV (AT(4)) receptor is the enzyme

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Genetic Variability Associated with Angiotensin Converting Enzyme (ACE) Gene Polymorphism in Sportsmen Pursuing Different Sports

., Carr, J. (2000). Angiotensin I-converting enzyme: Genotype and disease associations. J. Mol. Diag. , 2 (3), 105--115. Folland, J., Leach, B., Little, T., Hawker, K., Myerson, S., Montgomery, H., Jones, D. (2000). Angiotensin-converting enzyme genotype affects the response of human skeletal muscle to functional overload. Exp. Physiol. , 85 , 575--579. Gayagay, G., Yu, B., Hambly, B., Boston, T., Hahn, A., Celermajer, D.S., Trent, R.J. (1998). Elite endurance athletes and the ACE I allele: The role of genes in

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Adenosine pretreatment attenuates angiotensin II-mediated p38 MAPK activation in a protein kinase A dependent manner

, Boysen PG, Cohen MV, Downey JM. Cardioprotection with adenosine A2 receptor activation at reperfusion. J Cardiovasc Pharmacol. 2005; 46:794-802. 5. Sitkovsky MV. Use of the A2A adenosine receptor as a physiological immunosuppressor and to engineer inflammation in vivo. Biochem Pharmacol. 2003; 65: 493-501. 6. Mehta PK, Griendling KK. Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol. 2007; 292: 82-97. 7. Grote K, Drexler H, Schieffer B. Renin-angiotensin

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Renin–angiotensin–aldosterone system in insulin resistance and metabolic syndrome

hypertension. Antihypertensive drugs such as thiazide diuretics and β-blockers adversely affect glucose metabolism and increase the risk of developing type-2 diabetes [ 3 - 6 ] , though this has been disputed [ 7 - 11 ] . On the other hand, drugs that interfere with the renin–angiotensin system (RAS) improve insulin sensitivity, produce a significant decline of albuminuria, induce a drop of the pathological glomerular hyperfiltration, and reduce the incidence of new-onset diabetes [ 12 - 17 ] . Therefore, the initial selection of antihypertensive therapy for obese

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Angiotensin-Converting Enzyme Genotype and Acute Pancreatitis in Turkey

Gastroenterol 2005; 14(1): 53-61. Oruc N, Lamb J, Kutlu OC, Barmada MM, Money ME, Slivka A, Whitcomb DC. The functional angiotensin converting enzyme gene I/D polymorphism does not alter susceptibility to chronic pancreatitis JOP 2004; 5(6): 457-463. Oruc N, Papachristou G, Avula H, Slivka A, Lamb J, Whitcomb DC., Angiotensin-converting enzyme gene DD genotype neither increases susceptibility to acute pancreatitis nor influences disease severity. HPB (Oxford) 2009; 11(1): 45-49. Bhaskar S, Reddy

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The influence of renin angiotensin aldosterone system blockers on asymmetric dimethylarginine levels in patients with chronic glomerulonephritis

(ADMA): an endogenous inhibitor of nitric oxide synthase and a novel cardiovascular risk molecule. Med Sci Monit ., 15, RA91-101, 2009. 5. Deckert T., Feldt-Rasmussen B., Borch-Johnsen K. Albuminuria reflects widespread vascular damage. The Steno hypothesis. Diabetologia , 32, 219-226, 1989. 6. Fliser D. et al. Asymmetric dimethylarginine and progression of chronic kidney disease: the mild to moderate kidney disease study. J Am Soc Nephrol ., 16, 2456-2461, 2005. 7. Fujii H. et al. Renin-Angiotensin System Inhibitors Reduce Serum Asymmetric

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Cholangitis of Pancreatitis? Does the Angiotensin-Converting Enzyme Genotype Favor Either?

duct obstruction triggers acute necrotizing pancreatitis in the opposum. Gastroenterology 1993; 104(3): 853-861. Bhaskar S, Reddy DN, Mahurkar S, Rao GV, Singh L, Chandak GR. Lack of significant association of an insertion/deletion polymorphism in the angiotensin converting enzyme (ACE) gene with tropical calcific pancreatitis. BMC Gastroenterol 2006; 6:42-49. Paul M, Mehr AP, Kreutz R. Physiology of local renin-angiotensin systems. Physiol Rev 2006; 86(3): 747-803. Leung PS. The

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Role of angiotensin II on protein expression of renal nitric oxide synthase in unilateral ureteral obstructive rat

References 1. Hennington BS, Zhang H, Miller MT, Granger JP, Reckelhoff JF. Angiotensin II stimulates synthesis of endothelial nitric oxide synthase. Hypertension. 1998; 3:283-8. 2. Moreno C, Lopez A, Llinas MT, Rodriguez F, Lopez- Farre A, Nava E, et al. Changes in NOS activity and protein expression during acute and prolonged ANG II administration. Am J Physiol. 2002; 282:R31-7. 3. Kurtz A, Gotz K, Hamann M, Wagner C. Stimulation of renin secretion by NO doners is related to the cAMP pathway. Am J Physiol

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